yohimbine and morphine
yohimbine has been researched along with morphine in 141 studies
Research
Studies (141)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (38.30) | 18.7374 |
| 1990's | 33 (23.40) | 18.2507 |
| 2000's | 37 (26.24) | 29.6817 |
| 2010's | 16 (11.35) | 24.3611 |
| 2020's | 1 (0.71) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bonifazi, A; Del Bello, F; Diamanti, E; Giannella, M; Hudson, AL; Mammoli, V; Mattioli, L; Perfumi, M; Piergentili, A; Pigini, M; Quaglia, W; Titomanlio, F | 1 |
| Avery, BA; Behnke, M; Chear, NJ; Hiranita, T; Kamble, SH; León, F; McCurdy, CR; McMahon, LR; Obeng, S; Patel, A; Ramanathan, S; Reeves, ME; Restrepo, LF; Sharma, A | 1 |
| Chance, WT; Schechter, MD | 1 |
| Gomes, C; Svensson, TH; Trolin, G | 1 |
| Canevari, R; Gressier, H; Petitjean, M; Poignant, JC; Regnier, G | 1 |
| Colado, MI; Martin, MI | 1 |
| Garzón, J; Sánchez-Blázquez, P | 1 |
| Alamo, C; Alguacil, LF; Cuenca, E; Iglesias, V | 1 |
| Gebhart, GF; Zhuo, M | 1 |
| Brase, DA; Dewey, WL; Tripathi, HL; Ward, CR | 1 |
| Bartha, L; Hársing, LG; Kiem, DT; Makara, GB | 1 |
| Morrone, LA; Pimpinella, G; Romanelli, L; Valeri, P | 1 |
| Martinelli, B; Morrone, LA; Severini, C; Valeri, P | 1 |
| Dai, S; Wang, Y | 1 |
| Fujimoto, JM; Rady, JJ; Roerig, SC | 1 |
| Iversen, SD; Rupniak, NM; Samson, NA; Steventon, MJ | 1 |
| Wong, CL | 2 |
| Arts, KS; Fujimoto, JM; Holmes, BB | 1 |
| Collins, KA; Tseng, LF | 1 |
| Raffa, RB; Vaught, JL | 1 |
| Elsworth, JD; Lewis, VO; Pivirotto, P; Redmond, DE; Roth, RH; Taylor, JR | 1 |
| Englberger, W; Friderichs, E; Reimann, W; Schneider, J | 1 |
| Tang, R; Tseng, LF | 1 |
| Izenwasser, S; Kornetsky, C | 1 |
| Nance, PW; Sawynok, J | 1 |
| Ansuategui, M; Feria, M; Naharro, L | 1 |
| Fujimoto, JM; Suh, HH; Tseng, LL | 1 |
| Cascio, CS; Dallman, MF; Darlington, DN; Shinsako, J; Suemaru, S | 1 |
| Collins, JG; Kitahata, LM; Kumeta, Y; Murata, K; Nakagawa, I | 1 |
| Tang, R; Tseng, LL | 1 |
| Jurcovicová, J; Krulich, L; Le, T | 1 |
| Ben-Zvi, Z; Garty, M; Hurwitz, A | 1 |
| James, RC; Roberts, SM; Skoulis, NP | 1 |
| Allen, LG; Crowley, WR; Kalra, SP | 1 |
| Fredholm, BB; Lindgren, E | 1 |
| Kulkarni, SK; Parale, MP | 1 |
| Ben-Zvi, Z; Hurwitz, A | 1 |
| Reny-Palasse, V; Rips, R | 1 |
| Dashwood, MR; Dickenson, AH; Sullivan, AF | 1 |
| Ferreira, SH; Nakamura, M | 1 |
| Chinn, C; Horita, A; Yabase, M | 1 |
| Gebhart, GF; Solomon, RE | 1 |
| Alamo, C; Alguacil, LF; Cuenca, E; Santos, C | 1 |
| Wigdor, S; Wilcox, GL | 1 |
| Bardo, MT; Bhatnagar, RK; Schmidt, RH | 1 |
| Brown, OM; DiStefano, PS | 1 |
| Canellas, J; Demichel, P; Laubie, M; Roquebert, J; Schmitt, H | 1 |
| Apte, BK; Chaudhury, RR | 1 |
| Beckmann, H; Maturová, M; Wacker, A | 1 |
| Yamashita, T | 1 |
| Henriksson, BG; Järbe, TU | 1 |
| Dhasmana, KM; Dhawan, KN; Dixit, KS; Gupta, GP | 1 |
| Lang, WJ; Rush, M | 1 |
| Biemann, K | 1 |
| Collier, HO; Tucker, JF | 1 |
| Farsang, C; Kunos, G; Mucci, L; Ramirez-Gonzalez, MD | 1 |
| Edén, S; Eriksson, E; Modigh, K | 1 |
| Fielding, S; Lal, H; Spaulding, TC | 1 |
| Aceto, MD; May, EL | 1 |
| Atlas, D; Hynes, MD; Ruffolo, RR | 1 |
| Bardo, MT; Bhatnagar, RK; Gebhart, GF | 1 |
| Harden, TK; Smith, MM | 1 |
| Ahrens, F; Zhu, B | 1 |
| Aleixandre, MA; García de Jalón, PD; Martin, MI | 1 |
| Dwoskin, LP; Neal, BS; Sparber, SB | 1 |
| Barry, H; Krimmer, EC; McGuire, MS | 1 |
| Sanger, DJ | 1 |
| Inoue, K; Kohno, S; Murata, T; Ohata, K; Sakamoto, H | 1 |
| Blumberg, H; Slovak, DM | 1 |
| Gupta, VN; Pickworth, WB; Sharpe, LG | 1 |
| Boucher, F; Dennis, SG; Gutman, S; Melzack, R | 1 |
| Gear, RW; Gordon, NC; Heller, PH; Levine, JD | 1 |
| Henderson, CJ; Liu, Z; Rane, A; Wolf, CR | 1 |
| Dhawan, BN; Kumar, A; Raghubir, R | 1 |
| Driessen, B; Giertz, H; Reimann, W | 1 |
| Ansell, RJ; Mosbach, K; Ramström, O | 1 |
| Fang, F; Proudfit, HK | 1 |
| Alguacil, LF; Ambrosio, E; García-Lecumberri, C; Iglesias, V; Orensanz, L | 1 |
| Asai, T; Mapleson, WW; Power, I | 1 |
| El-Kadi, AO; Sharif, SI | 1 |
| Coudert, P; Couquelet, J; Fialip, J; Mavel, S; Rubat, C | 1 |
| Getslev, V; Pick, CG; Schreiber, S; Weizman, A | 1 |
| Bois, F; Coudert, P; Couquelet, J; Moreau, S; Rubat, C | 1 |
| Rao, VS; Santos, FA | 1 |
| de Wolff, MH; Leather, HA; Wouters, PF | 1 |
| Bebot, M; Coudert, P; Couquelet, J; Courteix, C; Fialip, J; Rubat, C | 1 |
| Laorden, ML; Milanés, MV | 1 |
| Chen, JY; Dafny, N; Kang, YM; Ouyang, W; Qiao, JT | 1 |
| Goto, T; Ochi, T | 1 |
| Abouazra, HA; Sharif, SI | 1 |
| Schiller, PW; Shimoyama, M; Shimoyama, N; Szeto, HH; Zhao, GM | 1 |
| Alguacil, LF; Morales, L; Perez-Garcia, C | 1 |
| Uzbay, IT; Yeşilyurt, O | 1 |
| Hough, LB; Leurs, R; Menge, WM; Nalwalk, JW; Svokos, K; Timmerman, H | 1 |
| Azizi, MR; Dehpour, AR; Farahani, M; Javidan, AN; Namiranian, K; Sadr, SS | 1 |
| Hayashi, M; Hoshi, K; Ichihara, K; Nakai, T; Wakabayashi, H | 1 |
| Bachtell, RK; Ryabinin, AE; Tsivkovskaia, NO | 1 |
| Dehpour, AR; Homayoun, H; Khavandgar, S | 1 |
| Kelley, AE; Schiltz, CA; Schroeder, BE | 1 |
| Homayoun, H; Khavandgar, S; Zarrindast, MR | 1 |
| Alguacil, LF; Herradón, G; Morales, L; Pérez-García, C | 1 |
| Assadi, E; Oryan, S; Sahebgharani, M; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Aricioglu, F; Dulger, G; Ercil, E | 1 |
| Aricioglu, F; Utkan, T | 1 |
| Aviles, M; González-Cuello, A; Laorden, ML; Milanés, MV | 1 |
| Dang, VC; Williams, JT | 1 |
| CHEYMOL, J; QUINQUAUD, A | 2 |
| Dehpour, AR; Ebrahimkhani, MR; Ghaffari, K; Homayoun, H; Honar, H; Jannati, A; Kiani, S; Noorian, AR; Rashidi, N; Riazi, K | 1 |
| Campanella, S; Dan, B; Hanak, C; Meyvaert, A; Pelc, I; Streel, E; Verbanck, P | 1 |
| Campos, AR; David, JM; David, JP; Lima-Júnior, RC; Maia, JL; Melo, CM; Rao, VS; Santos, FA | 1 |
| Cardinaletti, C; Carrieri, A; Gentili, F; Ghelfi, F; Mattioli, L; Perfumi, M; Pigini, M; Vesprini, C | 1 |
| Alguacil, LF; Alonso, E; Deuel, TF; Díez-Fernández, C; Ezquerra, L; Garrido, E; Herradón, G; Pérez-García, C | 1 |
| Alguacil, LF; Deuel, TF; Díez-Fernández, C; Ezquerra, L; Garrido, E; Herradón, G; Pérez-García, C | 1 |
| Ardenghi, JV; De Souza, MM; Filho, VC; Kanegusuku, M; Monache, FD; Niero, R; Yunes, RA | 1 |
| Amin, M; Rawls, SM; Zisk, J | 1 |
| Kardan, A; Mehr, SE; Samini, M | 1 |
| Cahill, CM; Jhamandas, K; Milne, B; Sutak, M | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A; Matwyshyn, G; Zhang, Z | 1 |
| Ding, Z; Raffa, RB | 1 |
| Albella, B; Alguacil, LF; González-Martín, C; Polanco, MJ; Segovia, JC | 1 |
| Adeyemi, OO; Akindele, AJ; Ogunleye, EA | 1 |
| Pettersen, VL; Raimundo, JM; Sudo, RT; Trachez, MM; Zapata-Sudo, G | 1 |
| Calasans-Maia, JA; Galdino, SL; Hernandes, MZ; Lima, MC; Pitta, IR; Sudo, RT; Zapata-Sudo, G | 1 |
| Heydari, F; Mehr, SE; Samini, M | 1 |
| Bhalla, S; Gulati, A; Rapolaviciute, V | 1 |
| Andurkar, SV; Bhalla, S; Gulati, A | 2 |
| Alguacil, LF; González-Martín, C; López-Giménez, JF; Polanco, MJ | 1 |
| Li, JX; Winter, JC; Zhang, Y | 1 |
| Andurkar, SV; Gulati, A | 1 |
| Alguacil, LF; González-Martín, C; Polanco, MJ | 1 |
| Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J | 1 |
| Caselli, G; Ferrari, F; Lanza, M; Menghetti, I; Tremolada, D | 1 |
| Bujalska-Zadrożny, M; Cegielska-Perun, K; Dybała, M; Siwek, A; Tatarkiewicz, J | 1 |
| Hashemi-Hezaveh, SM; Sheidadoust, H; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Kirby, LG; Li, C | 1 |
Reviews
1 review(s) available for yohimbine and morphine
| Article | Year |
|---|---|
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine | 1984 |
Trials
1 trial(s) available for yohimbine and morphine
| Article | Year |
|---|---|
Enhancement of morphine analgesia by the alpha 2-adrenergic antagonist yohimbine.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adult; Analgesics; Double-Blind Method; Drug Synergism; Humans; Male; Morphine; Pain Measurement; Pain, Postoperative; Tooth Extraction; Yohimbine | 1995 |
Other Studies
139 other study(ies) available for yohimbine and morphine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Favourable involvement of α2A-adrenoreceptor antagonism in the I₂-imidazoline binding sites-mediated morphine analgesia enhancement.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Humans; Idazoxan; Imidazolines; Male; Mice; Morphine; Pain Measurement; Receptors, Adrenergic, alpha-2; Stereoisomerism | 2012 |
Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids.
Topics: Adrenergic Agents; Analgesics; Animals; Blood Proteins; CHO Cells; Cricetulus; Dopamine Agents; Guinea Pigs; Humans; Microsomes, Liver; Rats; Receptors, Adrenergic; Receptors, Opioid; Secologanin Tryptamine Alkaloids | 2020 |
Autoanalgesia: blockade by yohimbine.
Topics: Analgesia; Animals; Electroshock; Male; Morphine; Rats; Reaction Time; Time Factors; Yohimbine | 1979 |
Evidence for involvement of central noradrenergic neurons in the cardiovascular depression induced by morphine in the rat.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Brain; Cardiovascular System; Clonidine; Heart Rate; Male; Morphine; Naloxone; Norepinephrine; Protriptyline; Rats; Reflex; Yohimbine | 1976 |
A new central direct dopaminergic stimulant: 1-(Coumaran-5-yl methyl)-4-(2-thiazolyl) piperazine hydrochloride (S 3608).
Topics: Animals; Apomorphine; Behavior, Animal; Benzofurans; Catatonia; Corpus Striatum; Drug Interactions; Ergolines; Humans; Hydroxydopamines; Male; Morphine; Piperazines; Rats; Stereotyped Behavior; Substantia Nigra; Thiazoles; Yohimbine | 1975 |
Effects of opioid and alpha 2-adrenoceptor agonists on the isolated ileum of morphine-dependent guinea-pigs during withdrawal and after clonidine treatment.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Drug Tolerance; Electric Stimulation; Guinea Pigs; Ileum; Male; Morphine; Morphine Dependence; Myenteric Plexus; Naloxone; Narcotics; Neuromuscular Junction; Substance Withdrawal Syndrome; Yohimbine | 1992 |
alpha N-acetyl human beta-endorphin-(1-31) alleviates the morphine withdrawal syndrome in rodents: a comparative study with clonidine.
Topics: Animals; beta-Endorphin; Clonidine; Disease Models, Animal; Male; Mice; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine | 1992 |
Effects of yohimbine on morphine analgesia and physical dependence in the rat.
Topics: Analgesia; Animals; Behavior, Animal; Delayed-Action Preparations; Male; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Yohimbine | 1992 |
Tonic cholinergic inhibition of spinal mechanical transmission.
Topics: Animals; Biogenic Monoamines; Cholinergic Antagonists; Drug Interactions; Endorphins; Hot Temperature; Injections, Spinal; Male; Morphine; Naloxone; Pain Measurement; Parasympatholytics; Physical Stimulation; Prazosin; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Adrenergic; Spinal Cord; Synaptic Transmission; Tail; Yohimbine | 1991 |
An insulin-independent mechanism of intrathecal morphine-induced hypoglycemia in mice: mediation through a central alpha-2 adrenergic pathway.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Body Temperature; Drug Interactions; Glucagon; Hypoglycemia; Injections, Spinal; Insulin; Male; Mice; Mice, Inbred ICR; Morphine; Receptors, Adrenergic, alpha; Yohimbine | 1991 |
Reevaluation of the role of alpha 2-adrenoreceptors in morphine-stimulated release of growth hormone.
Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Clonidine; Growth Hormone; Male; Morphine; Orchiectomy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Testosterone; Yohimbine | 1991 |
Some pharmacological characteristics of the guinea pig ileum opioid system activated by cholecystokinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Cholecystokinin; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Receptors, Opioid; Yohimbine | 1990 |
Reproducible withdrawal contractions of isolated guinea-pig ileum after brief morphine exposure: effects of clonidine and nifedipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nifedipine; Substance Withdrawal Syndrome; Yohimbine | 1990 |
Naloxone-induced cardiovascular depression in rats that had received chronic morphine-treatment.
Topics: Anesthesia; Animals; Arteries; Atropine; Blood Pressure; Cardiac Complexes, Premature; Clonidine; Heart; Hemodynamics; In Vitro Techniques; Male; Morphine; Muscle, Smooth, Vascular; Naloxone; Rats; Rats, Inbred Strains; Tail; Yohimbine | 1991 |
Heroin acts on different opioid receptors than morphine in Swiss Webster and ICR mice to produce antinociception.
Topics: Analgesia; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heroin; Injections, Intraventricular; Male; Methysergide; Mice; Mice, Inbred ICR; Morphine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Species Specificity; Spinal Cord; Yohimbine | 1991 |
Induction of cognitive impairment by scopolamine and noncholinergic agents in rhesus monkeys.
Topics: Amphetamine; Animals; Behavior, Animal; Cognition; Dronabinol; Lorazepam; Macaca mulatta; Male; Morphine; Phencyclidine; Scopolamine; Spatial Behavior; Yohimbine | 1991 |
Interaction between the inhibitory effects of morphine and clonidine on intestinal transit in mice.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Female; Gastrointestinal Transit; Intestines; Mice; Mice, Inbred ICR; Morphine; Naloxone; Time Factors; Yohimbine | 1991 |
Differential contribution of descending serotonergic and noradrenergic systems to central Tyr-D-Ala2-Gly-NMePhe4-Gly-ol5 (DAMGO) and morphine-induced antinociception in mice.
Topics: Analgesia; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Morphine; Serotonin; Yohimbine | 1991 |
Different mechanisms mediating tail-flick inhibition induced by beta-endorphin, DAMGO and morphine from ROb and GiA in anesthetized rats.
Topics: Analgesia; Animals; beta-Endorphin; Brain Stem; Diffusion; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Methysergide; Morphine; Naloxone; Raphe Nuclei; Rats; Rats, Inbred Strains; Yohimbine | 1991 |
Centrally-mediated antinociceptive action of RWJ-22757 (formerly McN-5195): involvement of spinal descending inhibitory pathways (an hypothesis).
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Indolizines; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Morphine; Naloxone; Phentolamine; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1991 |
Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats.
Topics: Analgesics; Animals; Behavior, Animal; Drug Implants; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Substance Withdrawal Syndrome; Yohimbine | 1991 |
Analgesic and antitussive properties of EM 405.
Topics: Analgesia; Animals; Antitussive Agents; Brain; Cell Membrane; Cough; Cyclohexanes; Cyclohexenes; Guinea Pigs; Hypothalamus; Morphine; Naloxone; Norepinephrine; Rats; Synaptosomes; Yohimbine | 1991 |
Different mechanisms mediate beta-endorphin- and morphine-induced inhibition of the tail-flick response in rats.
Topics: Analgesia; Animals; beta-Endorphin; Efferent Pathways; Male; Microinjections; Morphine; Naloxone; Periaqueductal Gray; Rats; Rats, Inbred Strains; Receptors, Opioid; Yohimbine | 1990 |
Effects of clonidine and yohimbine, alone and in combination with morphine, on supraspinal analgesia.
Topics: Analgesics; Animals; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Rats; Rats, Inbred F344; Yohimbine | 1990 |
Substance P-induced long-term blockade of spinal adrenergic analgesia: reversal by morphine and naloxone.
Topics: Analgesia; Animals; Clonidine; Kinetics; Male; Morphine; Naloxone; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Time Factors; Yohimbine | 1987 |
Noradrenergic and opioidergic influences on the antinociceptive effect of clomipramine in the formalin test in rats.
Topics: Analgesics; Animals; Clomipramine; Endorphins; Female; Formaldehyde; Morphine; Naloxone; Norepinephrine; Pain Measurement; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Differential mechanisms mediating beta-endorphin- and morphine-induced analgesia in mice.
Topics: Analgesia; Animals; beta-Endorphin; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Morphine; Naloxone; Reaction Time; Yohimbine | 1989 |
Role of alpha-adrenergic mechanism in effects of morphine on the hypothalamo-pituitary-adrenocortical and cardiovascular systems in the rat.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Blood Pressure; Corticosterone; Heart Rate; Hypothalamo-Hypophyseal System; Male; Morphine; Pituitary-Adrenal System; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Yohimbine | 1989 |
Intrathecal clonidine suppresses noxiously evoked activity of spinal wide dynamic range neurons in cats.
Topics: Analgesics; Animals; Blood Pressure; Cats; Clonidine; Decerebrate State; Drug Combinations; Female; Injections, Spinal; Male; Morphine; Neurons; Pain; Receptors, Adrenergic, alpha; Spinal Cord; Spinothalamic Tracts; Synaptic Transmission; Yohimbine | 1989 |
Differential actions of the blockade of spinal opioid, adrenergic and serotonergic receptors on the tail-flick inhibition induced by morphine microinjected into dorsal raphe and central gray in rats.
Topics: Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mesencephalon; Methysergide; Morphine; Naloxone; Pain; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Receptors, Serotonin; Spinal Cord; Yohimbine | 1989 |
Prolactin (PRL) release-inhibiting properties of the alpha 2 adrenergic receptor antagonist idazoxan: comparison with yohimbine.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Clonidine; Dioxanes; Dioxins; Growth Hormone; Idazoxan; Kinetics; Male; Morphine; Norepinephrine; Prazosin; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Restraint, Physical; Yohimbine | 1989 |
Interaction of clonidine and morphine with lidocaine in mice and rats.
Topics: Animals; Blood Gas Analysis; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Hypoxia; Lethal Dose 50; Lidocaine; Male; Mice; Morphine; Rats; Yohimbine | 1989 |
A centrally-mediated effect of morphine to diminish hepatocellular glutathione.
Topics: Adrenalectomy; Animals; Epinephrine; Glutathione; Hydrocortisone; Injections, Intraventricular; Liver; Male; Mice; Mice, Inbred ICR; Morphine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Yohimbine | 1987 |
Interactions between neuropeptide Y and adrenergic systems in the stimulation of luteinizing hormone release in steroid-primed ovariectomized rats.
Topics: Animals; Estradiol; Female; Luteinizing Hormone; Morphine; Neuropeptide Y; Ovariectomy; Phenoxybenzamine; Progesterone; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Opioid; Yohimbine | 1987 |
Protein kinase C activation increases noradrenaline release from the rat hippocampus and modifies the inhibitory effect of alpha 2-adrenoceptor and adenosine A1-receptor agonists.
Topics: Animals; Cyclic AMP; Electric Stimulation; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; Morphine; Norepinephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Purinergic; Yohimbine | 1988 |
Apparent pA2 estimates for an antinociceptive receptor.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Mice; Morphine; Naloxone; Nociceptors; Reaction Time; Receptors, Adrenergic, alpha; Yohimbine | 1985 |
Effects of morphine and clonidine on sulphobromophthalein disposition in mice.
Topics: Animals; Bile; Clonidine; Liver; Male; Mice; Morphine; Naloxone; Sulfobromophthalein; Yohimbine | 1986 |
Potentiation by TRH of the effect of imipramine on the forced-swimming test.
Topics: Animals; Drug Synergism; Drug Tolerance; Imipramine; Male; Mice; Morphine; Naloxone; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Opioid; Swimming; Thyrotropin-Releasing Hormone; Yohimbine | 1985 |
A study on the antagonism of the intestinal inhibitory effects of morphine and clonidine by yohimbine in mice.
Topics: Animals; Clonidine; Female; Gastrointestinal Motility; Mice; Mice, Inbred ICR; Morphine; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Alpha 2-adrenoceptor modulation of nociception in rat spinal cord: location, effects and interactions with morphine.
Topics: Animals; Autoradiography; Clonidine; Dihydromorphine; Drug Interactions; Electrophysiology; In Vitro Techniques; Injections, Spinal; Male; Morphine; Naloxone; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Spinal Cord; Yohimbine | 1987 |
Peripheral analgesic action of clonidine: mediation by release of endogenous enkephalin-like substances.
Topics: Analgesics; Animals; Carrageenan; Clonidine; Dinoprostone; Drug Tolerance; Enkephalins; Male; Morphine; Naloxone; Peripheral Nerves; Prostaglandins E; Rats; Rats, Inbred Strains; Yohimbine | 1988 |
Clonidine activates a cholinergic hippocampal theta rhythm in the rat.
Topics: Animals; Clonidine; Electroencephalography; Hippocampus; Male; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Reference Values; Scopolamine; Theta Rhythm; Yohimbine | 1988 |
Intrathecal morphine and clonidine: antinociceptive tolerance and cross-tolerance and effects on blood pressure.
Topics: Animals; Blood Pressure; Clonidine; Drug Administration Schedule; Drug Tolerance; Injections, Spinal; Male; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Reference Values; Spinal Cord; Yohimbine | 1988 |
Yohimbine reduces morphine tolerance in guinea-pig ileum.
Topics: Animals; Clonidine; Drug Tolerance; Female; Guanfacine; Guanidines; Guinea Pigs; Ileum; Male; Morphine; Muscle, Smooth; Phenylacetates; Yohimbine | 1987 |
Central and systemic morphine-induced antinociception in mice: contribution of descending serotonergic and noradrenergic pathways.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Morphine; Norepinephrine; Phentolamine; Serotonin; Spinal Cord; Yohimbine | 1987 |
Effects of morphine on sprouting of locus coeruleus fibers in the neonatal rat.
Topics: Adrenergic Fibers; Animals; Animals, Newborn; Clonidine; Drug Interactions; Female; Hydroxydopamines; Locus Coeruleus; Male; Morphine; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Regeneration; Yohimbine | 1985 |
Biochemical correlates of morphine withdrawal. 2. Effects of clonidine.
Topics: Adrenal Glands; Animals; Clonidine; Denervation; Dose-Response Relationship, Drug; Epinephrine; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Yohimbine | 1985 |
Centrally mediated bradycardia and hypotension induced by narcotic analgesics: dextromoramide and fentanyl.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Atropine; Blood Pressure; Cardiac Output; Cerebral Ventricles; Cisterna Magna; Dextromoramide; Dogs; Dose-Response Relationship, Drug; Female; Fentanyl; Heart Rate; Injections; Injections, Intra-Arterial; Injections, Intravenous; Male; Morphine; Nalorphine; Oxotremorine; Physostigmine; Pons; Spinal Cord; Yohimbine | 1974 |
An isolated guinea pig kidney perfusion preparation for studying the effect of pharmacologically active substances.
Topics: Aldosterone; Angiotensin II; Animals; Diuresis; Epinephrine; Guanethidine; Guinea Pigs; Histamine; Hydrochlorothiazide; In Vitro Techniques; Kidney; Morphine; Norepinephrine; Organomercury Compounds; Perfusion; Regional Blood Flow; Reserpine; Serotonin; Urea; Vasopressins; Yohimbine | 1966 |
[Inhibition, with alkaloids, of the steroid-dependent enzyme induction in Pseudomonas testosteroni].
Topics: Bacterial Proteins; Cell-Free System; Colchicine; Cortisone; Depression, Chemical; Desoxycorticosterone; Enzyme Induction; Ergot Alkaloids; Ergotamine; Estrone; Hydroxysteroid Dehydrogenases; Isomerases; Morphine; Papaverine; Progesterone; Pseudomonas; Reserpine; RNA, Messenger; Sparteine; Testosterone; Vinblastine; Yohimbine | 1967 |
[Effects of various drugs on the contraction of the excised vas deferens by hypogastric nerve and transmural stimulations in guinea pigs].
Topics: Abdominal Muscles; Acetylcholine; Animals; Atropine; Bretylium Compounds; Dibenzylchlorethamine; Electric Stimulation; Ganglionic Blockers; Guanidines; Guinea Pigs; Hypogastric Plexus; In Vitro Techniques; Male; Morphine; Muscle Contraction; Norepinephrine; Papaverine; Physostigmine; Procaine; Stimulation, Chemical; Vas Deferens; Yohimbine | 1967 |
Discriminative response control produced with hashish, tetrahydrocannabinols (delta 8-THC and delta 9-THC), and other drugs.
Topics: Amphetamine; Animals; Atropine; Avoidance Learning; Cannabis; Chlordiazepoxide; Chlorpromazine; Choice Behavior; Cocaine; Cues; Diazepam; Discrimination, Psychological; Dronabinol; Ketamine; Levallorphan; Male; Morphine; Pentobarbital; Phencyclidine; Physostigmine; Psilocybin; Rats; Scopolamine; Transfer, Psychology; Yohimbine | 1974 |
Blockade of depressor response of dopamine.
Topics: Animals; Apomorphine; Blood Pressure; Cats; Chlorpromazine; Codeine; Dopamine; Female; Male; Meperidine; Morphine; Phenothiazines; Phenoxybenzamine; Yohimbine | 1969 |
A comparison of conditional responses induced by various drugs.
Topics: Animals; Atropine; Conditioning, Psychological; Dogs; Electrocardiography; Gastric Juice; Heart Rate; Humans; Morphine; Nicotine; Phentolamine; Salivation; Yohimbine | 1969 |
Mass spectrometry of selected natural products.
Topics: Alkaloids; Chemical Phenomena; Chemistry, Physical; Morphine; Papaverine; Spectrum Analysis; Yohimbine | 1966 |
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine | 1980 |
Importance of norepinephrine alpha 2-receptor activation for morphine-induced rat growth hormone secretion.
Topics: Animals; Clonidine; Fenclonine; Growth Hormone; Haloperidol; Kinetics; Male; Morphine; Norepinephrine; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Yohimbine | 1981 |
Antinociceptive actions of clonidine.
Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Morphine; Muridae; Naloxone; Nociceptors; Phenoxybenzamine; Premedication; Receptors, Adrenergic; Receptors, Opioid; Spinal Cord; Yohimbine | 1981 |
Antinociceptive studies of the optical isomers of N-allylnormetazocine (SKF 10,047).
Topics: Analgesics; Animals; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Phenazocine; Receptors, Adrenergic, alpha; Receptors, Opioid; Stereoisomerism; Yohimbine | 1983 |
Antinociceptive activity of N-(4-hydroxyphenacetyl)-4-aminoclonidine, a novel analog of clonidine: role of opioid receptors and alpha-adrenoceptors.
Topics: Analgesics; Animals; Aorta, Thoracic; Benzeneacetamides; Clonidine; Dose-Response Relationship, Drug; Drug Antagonism; Kinetics; Male; Mice; Morphine; Naloxone; Receptors, Adrenergic, alpha; Receptors, Opioid; Xylazine; Yohimbine | 1983 |
Chronic naltrexone increases opiate binding in brain and produces supersensitivity to morphine in the locus coeruleus of the rat.
Topics: Animals; Brain; Etorphine; Locus Coeruleus; Male; Morphine; Naloxone; Naltrexone; Narcotics; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Synaptic Transmission; Yohimbine | 1983 |
Modification of receptor-mediated inhibition of adenylate cyclase in NG108-15 neuroblastoma X glioma cells by n-ethylmaleimide.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Epinephrine; Ethylmaleimide; Glioma; GTP-Binding Proteins; Morphine; Naloxone; Neuroblastoma; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Opioid; Yohimbine | 1984 |
Antisecretory effects of berberine with morphine, clonidine, L-phenylephrine, yohimbine or neostigmine in pig jejunum.
Topics: Animals; Berberine; Berberine Alkaloids; Body Water; Drug Interactions; Electrolytes; Enterotoxins; Escherichia coli; Jejunum; Male; Morphine; Muscle, Smooth; Neostigmine; Phenylephrine; Swine; Yohimbine | 1983 |
Changes in clonidine effect on longitudinal muscle-myenteric plexus strip preparation by morphine treatments.
Topics: Animals; Clonidine; Guinea Pigs; Morphine; Muscle, Smooth; Myenteric Plexus; Naloxone; Prazosin; Yohimbine | 1983 |
Yohimbine exacerbates and clonidine attenuates acute morphine withdrawal in rats.
Topics: Animals; Behavior, Animal; Clonidine; Drug Interactions; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reinforcement Schedule; Substance Withdrawal Syndrome; Yohimbine | 1983 |
Effects of the training dose on generalization of morphine stimulus to clonidine.
Topics: Animals; Clonidine; Conditioning, Operant; Discrimination Learning; Generalization, Stimulus; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Yohimbine | 1984 |
An analysis of the effects of systemically administered clonidine on the food and water intake of rats.
Topics: Animals; Clonidine; Drinking; Drug Interactions; Eating; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Time Factors; Yohimbine | 1983 |
[Studies on the antinociceptive activity of guanabenz, with particular reference to clonidine and morphine (author's transl)].
Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Guanabenz; Guanidines; Guinea Pigs; Ileum; In Vitro Techniques; Locomotion; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
Effects of yohimbine and naltrexone in counteraction of the morphine Straub tail and the amphetamine-potentiated morphine Straub tail in mice.
Topics: Amphetamine; Animals; Male; Mice; Morphine; Naloxone; Naltrexone; Phentolamine; Tail; Yohimbine | 1982 |
Morphine-like effects of clonidine on the EEG, slow wave sleep and behavior in the dog.
Topics: Animals; Autonomic Nervous System; Behavior, Animal; Clonidine; Dogs; Electroencephalography; Injections, Intravenous; Injections, Intraventricular; Male; Morphine; Naloxone; Sleep; Yohimbine | 1982 |
Pain modulation by adrenergic agents and morphine as measured by three pain tests.
Topics: Animals; Drug Interactions; Male; Methods; Morphine; Naloxone; Pain; Rats; Reaction Time; Sympathomimetics; Time Factors; Yohimbine | 1980 |
Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism?
Topics: Adrenal Glands; Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Clonidine; Cortodoxone; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desoxycorticosterone; Drug Interactions; Drug Therapy, Combination; Gene Expression Regulation; Isoenzymes; Kidney; Liver; Male; Meperidine; Molecular Sequence Data; Morphine; Neurosecretory Systems; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 16-alpha-Hydroxylase; Steroids; Yohimbine | 1995 |
Analgesic effect of morphine, clonidine and serotonin microinjected into the PTN of rats.
Topics: Analgesics; Animals; Clonidine; Male; Methysergide; Microinjections; Morphine; Naloxone; Pain Measurement; Rats; Serotonin; Superior Colliculi; Yohimbine | 1993 |
Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro.
Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Chinchilla; Cocaine; Dopamine; Female; In Vitro Techniques; Male; Morphine; Naloxone; Norepinephrine; Rabbits; Rats; Rats, Sprague-Dawley; Stereoisomerism; Synaptosomes; Tramadol; Yohimbine | 1993 |
Towards artificial antibodies prepared by molecular imprinting.
Topics: Antibodies; Atrazine; Binding, Competitive; Corticosterone; Cross Reactions; Diazepam; Enkephalin, Leucine; Enzyme-Linked Immunosorbent Assay; Humans; Hydrocortisone; Kinetics; Methylglucosides; Molecular Mimicry; Morphine; Polymers; Propranolol; Radioimmunoassay; Stereoisomerism; Theophylline; Yohimbine | 1996 |
Spinal cholinergic and monoamine receptors mediate the antinociceptive effect of morphine microinjected in the periaqueductal gray on the rat tail, but not the feet.
Topics: Animals; Atropine; Biogenic Monoamines; Female; Foot; Injections, Spinal; Methysergide; Microinjections; Morphine; Naloxone; Nociceptors; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cholinergic; Spinal Cord; Tail; Yohimbine | 1996 |
Effect of yohimbine on the development of morphine dependence in the rat: lack of involvement of cortical beta-adrenoceptor modifications.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Cerebral Cortex; Drug Evaluation, Preclinical; Drug Tolerance; Male; Morphine; Morphine Dependence; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Up-Regulation; Yohimbine | 1997 |
Differential effects of clonidine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Gastric Emptying; Gastrointestinal Transit; Imidazoles; Male; Medetomidine; Morphine; Naloxone; Rats; Rats, Wistar; Yohimbine | 1997 |
The influence of chronic treatment with clonidine, yohimbine and idazoxan on morphine withdrawal.
Topics: Adrenergic Agents; Animals; Clonidine; Drug Interactions; Idazoxan; Male; Mice; Morphine; Narcotics; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Yohimbine | 1997 |
Effects of two N-arylpiperazinylmethylpyrazolo [1,5-d][1,2,4]triazine derivatives in pain and antidepressant tests in mice.
Topics: Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Antidepressive Agents; Central Nervous System Depressants; Drug Interactions; Immobilization; Male; Mice; Morphine; Narcotic Antagonists; Pain Measurement; Pyrazoles; Reaction Time; Serotonin Antagonists; Triazines; Yohimbine | 1997 |
The antinociceptive effect of moclobemide in mice is mediated by noradrenergic pathways.
Topics: Analgesics; Animals; Benzamides; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Intraperitoneal; Injections, Spinal; Injections, Subcutaneous; Male; Metergoline; Mice; Mice, Inbred ICR; Moclobemide; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Neural Pathways; Norepinephrine; Receptors, Adrenergic, alpha-2; Serotonin; Yohimbine | 1998 |
Spirobutenolides substituted by arylpiperazinyl-carbonyl moieties. Synthesis and antinociceptive properties.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzoquinones; Drug Synergism; Furans; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Pain Measurement; Reaction Time; Spiro Compounds; Yohimbine | 1998 |
Quinine-induced inhibition of gastrointestinal transit in mice: possible involvement of endogenous opioids.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Gastrointestinal Transit; Glyburide; Male; Mice; Minoxidil; Morphine; Naloxone; Narcotic Antagonists; Opioid Peptides; Potassium Channels; Quinine; Yohimbine | 1999 |
Effects of tramadol on minimum alveolar concentration (MAC) of isoflurane in rats.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Drug Interactions; Isoflurane; Male; Morphine; Naloxone; Narcotic Antagonists; Pulmonary Alveoli; Rats; Rats, Wistar; Tramadol; Yohimbine | 1999 |
Synthesis and analgesic effects of 5-[4-(arylpiperazin-1-yl)alkylamino]-4-benzyl-3-methyl-1,2-oxa zin-6-one s.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Benzoquinones; Binding, Competitive; Brain Chemistry; Drug Synergism; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Oxazines; Pain Measurement; Piperazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Yohimbine | 2000 |
Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Catecholamines; Dopamine; Heart Ventricles; Male; Morphine; Morphine Dependence; Norepinephrine; Normetanephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2000 |
Norepinephrine modulates single hypothalamic arcuate neurons via alpha(1)and beta adrenergic receptors.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium; Cromakalim; Female; Glyburide; In Vitro Techniques; Locus Coeruleus; Magnesium; Male; Morphine; Naloxone; Neural Inhibition; Neural Pathways; Neurons; Norepinephrine; Phentolamine; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Yohimbine | 2000 |
The antinociceptive effect of FR140423 in mice: involvement of spinal alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Nociceptors; Pain Measurement; Phentolamine; Prazosin; Propranolol; Pyrazoles; Receptors, Adrenergic, alpha-2; Spinal Cord; Sulfoxides; Yohimbine | 2000 |
Hyperglycaemia: a morphine-like effect produced by naloxone.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Dioxanes; Hyperglycemia; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rabbits; Receptors, Adrenergic, alpha-2; Yohimbine | 2001 |
Antinociceptive and respiratory effects of intrathecal H-Tyr-D-Arg-Phe-Lys-NH2 (DALDA) and [Dmt1] DALDA.
Topics: Analgesics; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Spinal; Male; Morphine; Naloxone; Norepinephrine; Oligopeptides; Rats; Rats, Sprague-Dawley; Respiration; Serotonin; Yohimbine | 2001 |
Effects of yohimbine on the antinociceptive and place conditioning effects of opioid agonists in rodents.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzamides; Conditioning, Psychological; Drug Synergism; Hot Temperature; Male; Mice; Morphine; Motor Activity; Pain; Pain Measurement; Piperazines; Rats; Rats, Sprague-Dawley; Reaction Time; Tail; Yohimbine | 2001 |
Agmatine potentiates the analgesic effect of morphine by an alpha(2)-adrenoceptor-mediated mechanism in mice.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Male; Mice; Morphine; Nociceptors; Pain; Pain Measurement; Rats; Receptors, Adrenergic, alpha-2; Yohimbine | 2001 |
A role for spinal, but not supraspinal, alpha(2) adrenergic receptors in the actions of improgan, a powerful, non-opioid analgesic.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cimetidine; Clonidine; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Yohimbine | 2001 |
Lithium inhibits the development of physical dependence to clonidine in mice.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Clonidine; Injections, Intraperitoneal; Lithium; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Substance-Related Disorders; Yohimbine | 2002 |
Noradrenaline release in rat locus coeruleus is regulated by both opioid and alpha(2) -adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Injections, Intraventricular; Locus Coeruleus; Male; Microdialysis; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Substance Withdrawal Syndrome; Yohimbine | 2002 |
Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms.
Topics: Aminoacetonitrile; Animals; Brain; Chlordiazepoxide; Dopamine; Ethanol; Gene Expression Regulation; Genes, fos; Haloperidol; Male; Mice; Mice, Inbred C57BL; Morphine; Norepinephrine; Pregnanolone; Protease Inhibitors; Signal Transduction; Tyrosine 3-Monooxygenase; Yohimbine | 2002 |
The role of alpha2-adrenoceptors in the modulatory effects of morphine on seizure susceptibility in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Differential Threshold; Disease Susceptibility; Male; Mice; Mice, Inbred Strains; Morphine; Narcotics; Receptors, Adrenergic, alpha; Seizures; Stress, Physiological; Yohimbine | 2002 |
Neural activation profile elicited by cues associated with the anxiogenic drug yohimbine differs from that observed for reward-paired cues.
Topics: Adrenergic alpha-Antagonists; Animals; Anxiety; Cacao; Conditioning, Operant; Cues; Environment; Genes, fos; Immunohistochemistry; Male; Morphine; Motor Activity; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reward; Yohimbine | 2003 |
Morphine state-dependent learning: interactions with alpha2-adrenoceptors and acute stress.
Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Male; Memory; Mice; Morphine; Narcotics; Reaction Time; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Restraint, Physical; Stress, Physiological; Time Factors; Yohimbine | 2003 |
The contribution of alpha2-adrenoceptor and opioid receptor mechanisms to antinociception differs in Lewis and Fischer 344 rats.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Morphine; Naloxone; Pain Threshold; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Species Specificity; Time Factors; Yohimbine | 2003 |
Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Histamine; Histamine H2 Antagonists; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Prazosin; Propranolol; Pyrilamine; Receptors, Histamine H2; Yohimbine | 2003 |
Effects of imipramine on the expression and development of morphine dependence in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clonidine; Dose-Response Relationship, Drug; Imipramine; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
Agmatine inhibits naloxone-induced contractions in morphine-dependent Guinea pig ileum.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Idazoxan; Ileum; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine | 2003 |
Inhibitory effect of harmane on morphine-dependent Guinea pig ileum.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Guinea Pigs; Harmine; Idazoxan; Ileum; In Vitro Techniques; Male; Morphine; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Yohimbine | 2003 |
Changes in c-fos expression in the rat heart during morphine withdrawal. Involvement of alpha2-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Blotting, Western; Body Weight; Drug Administration Schedule; Drug Therapy, Combination; Gene Expression; Genes, fos; Heart Ventricles; Immunohistochemistry; Injections, Subcutaneous; Male; Morphine; Myocytes, Cardiac; Naloxone; Normetanephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Substance Withdrawal Syndrome; Time Factors; Yohimbine | 2004 |
Chronic morphine treatment reduces recovery from opioid desensitization.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine | 2004 |
[Preservation of the emetic power of apomorphine injected subcutaneously in the presence of yohimbine].
Topics: Apomorphine; Emetics; Humans; Morphine; Yohimbine | 1950 |
The synergistic anticonvulsant effect of agmatine and morphine: possible role of alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Agmatine; Analysis of Variance; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Morphine; Pentylenetetrazole; Receptors, Adrenergic, alpha-2; Seizures; Yohimbine | 2005 |
A pharmacological modulation of opiate withdrawal using an up-/down-regulation of the noradrenergic system in opiate-dependent rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Male; Morphine; Morphine Dependence; Narcotics; Norepinephrine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Up-Regulation; Yohimbine | 2006 |
Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Capsaicin; Coloring Agents; Enzyme Inhibitors; Glyburide; Hypoglycemic Agents; KATP Channels; Lamiaceae; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Oleanolic Acid; Pain; Pain Measurement; Postural Balance; Potassium Channels, Inwardly Rectifying; Ruthenium Red; Yohimbine | 2006 |
Involvement of I2-imidazoline binding sites in positive and negative morphine analgesia modulatory effects.
Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Benzofurans; CHO Cells; Cricetinae; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Mice; Models, Molecular; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Radioligand Assay; Reaction Time; Receptors, Adrenergic, alpha-2; Receptors, Drug; Receptors, Opioid, mu; Yohimbine | 2006 |
Yohimbine prevents morphine-induced changes of glial fibrillary acidic protein in brainstem and alpha2-adrenoceptor gene expression in hippocampus.
Topics: Adrenergic alpha-Antagonists; Animals; Astrocytes; Autonomic Pathways; Biomarkers; Brain Stem; Disease Models, Animal; Down-Regulation; Gene Expression; Glial Fibrillary Acidic Protein; Hippocampus; Locus Coeruleus; Male; Morphine; Morphine Dependence; Narcotics; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; RNA, Messenger; Solitary Nucleus; Up-Regulation; Yohimbine | 2007 |
Morphine and yohimbine regulate midkine gene expression in the rat hippocampus.
Topics: Analgesics, Opioid; Animals; Cytokines; Gene Expression Regulation; Hippocampus; Male; Midkine; Morphine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Yohimbine | 2007 |
Analysis of the mechanism of antinociceptive action of niga-ichigoside F1 obtained from Rubus imperialis (Rosaceae).
Topics: Analgesics; Animals; Apomorphine; Atropine; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Morphine; Naloxone; Nitroarginine; Pain; Pain Measurement; Plant Extracts; Rosaceae; Saponins; Yohimbine | 2006 |
Agmatine blocks morphine-evoked hyperthermia in rats.
Topics: Agmatine; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Biogenic Amines; Body Temperature Regulation; Dose-Response Relationship, Drug; Drug Interactions; Fever; Idazoxan; Imidazoline Receptors; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Drug; Receptors, Opioid, mu; Yohimbine | 2007 |
Alpha-2 agonists decrease expression of morphine-induced conditioned place preference.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Clonidine; Conditioning, Operant; Male; Mice; Morphine; Receptors, Adrenergic, alpha-2; Reward; Xylazine; Yohimbine | 2008 |
Low doses of alpha 2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Idazoxan; Imidazoles; Male; Mianserin; Mirtazapine; Morphine; Rats; Rats, Sprague-Dawley; Spine; Yohimbine | 2008 |
Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Area Under Curve; Clonidine; Dansyl Compounds; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors; Yohimbine | 2009 |
Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aminoquinolines; Analgesics, Opioid; Anesthetics, Local; Animals; Benzamides; Brain; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fentanyl; GTP-Binding Proteins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Okadaic Acid; Oligonucleotides, Antisense; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Pertussis Toxin; Phosphoprotein Phosphatases; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, Opioid; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Yohimbine | 2009 |
Yohimbine prevents the effect of morphine on the redox status of neuroblastomaxglioma NG108-15 cells.
Topics: Caspases; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Humans; Mitochondria; Morphine; Neuroblastoma; Oxidation-Reduction; Yohimbine | 2009 |
Evaluation of the antidiarrhoeal effect of Sanseviera liberica Gerome & Labroy (Agavaceae) root extract.
Topics: Adrenergic alpha-Antagonists; Animals; Antidiarrheals; Castor Oil; Diarrhea; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Transit; Intestines; Isosorbide Dinitrate; Male; Medicine, African Traditional; Mice; Morphine; Narcotics; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; Rats; Sansevieria; Vasodilator Agents; Yohimbine | 2009 |
The synergistic interaction between morphine and maprotiline after intrathecal injection in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Injections, Spinal; Male; Maprotiline; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Selective Serotonin Reuptake Inhibitors; Time Factors; Yohimbine | 2009 |
Interaction of morphine with a new alpha2-adrenoceptor agonist in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Imidazolidines; Isoindoles; Male; Mice; Models, Molecular; Morphine; Pain; Random Allocation; Receptors, Adrenergic, alpha-2; Yohimbine | 2010 |
alpha(1)- and alpha(2)-Adrenoceptor hyporesponsiveness in isolated bisected vas deferens of bile duct-ligated rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Animals; Bile Ducts, Extrahepatic; Cholestasis, Extrahepatic; Clonidine; Electric Stimulation; In Vitro Techniques; Ligation; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vas Deferens; Yohimbine | 2010 |
The emising power of apormorphine and methylene blue, in the presence of yohimbine.
Topics: Humans; Methylene Blue; Morphine; Yohimbine | 1945 |
Determination of α(2)-adrenoceptor and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by agmatine and BMS182874.
Topics: Agmatine; Analgesics; Animals; Dansyl Compounds; Drug Synergism; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Oxycodone; Receptors, Adrenergic, alpha-2; Receptors, Endothelin; Yohimbine | 2011 |
Study of adrenergic, imidazoline, and endothelin receptors in clonidine-, morphine-, and oxycodone-induced changes in rat body temperature.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Body Temperature; Body Temperature Regulation; Brain; Clonidine; Dansyl Compounds; Drug Synergism; Endothelin A Receptor Antagonists; Idazoxan; Imidazoline Receptors; Male; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Yohimbine | 2011 |
Yohimbine does not affect opioid receptor activation but prevents adenylate cyclase regulation by morphine in NG108-15 cells.
Topics: Adenylyl Cyclases; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Cell Culture Techniques; Cell Line, Tumor; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Proteins; Humans; Morphine; Protein Binding; Receptors, Adrenergic, alpha-2; Receptors, Opioid, delta; Yohimbine | 2011 |
Morphine-induced antinociception in the rat: supra-additive interactions with imidazoline I₂ receptor ligands.
Topics: Adrenergic alpha-2 Receptor Antagonists; Agmatine; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Disease Models, Animal; Drug Synergism; Idazoxan; Imidazoles; Imidazoline Receptors; Ligands; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Yohimbine | 2011 |
Assessment of the analgesic effect of centhaquin in mouse tail flick and hot-plate tests.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Antihypertensive Agents; Body Temperature; Drug Interactions; Endothelin A Receptor Antagonists; Hot Temperature; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain; Piperazines; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Receptors, Opioid; Yohimbine | 2011 |
Involvement of α₂-adrenoceptors, imidazoline, and endothelin-A receptors in the effect of agmatine on morphine and oxycodone-induced hypothermia in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Agmatine; Animals; Body Temperature Regulation; Dansyl Compounds; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Hypothermia; Idazoxan; Imidazoline Receptors; Male; Mice; Morphine; Oxycodone; Receptor, Endothelin A; Receptors, Adrenergic, alpha-2; Yohimbine | 2013 |
Pro-apoptotic properties of morphine in neuroblastoma × glioma NG108-15 hybrid cells: modulation by yohimbine.
Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; DNA Fragmentation; Glioma; Hybrid Cells; In Situ Nick-End Labeling; Mice; Morphine; Necrosis; Neuroblastoma; Receptors, Opioid, delta; Yohimbine | 2014 |
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; Fenclonine; Hyperalgesia; Male; Mice; Morphine; Pain, Postoperative; Receptor, Adenosine A1; Xanthines; Yohimbine | 2013 |
Modulation of imidazoline I2 binding sites by CR4056 relieves postoperative hyperalgesia in male and female rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Benzofurans; Binding Sites; Drug Synergism; Female; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Morphine; Naloxone; Narcotic Antagonists; Pain, Postoperative; Quinazolines; Rats, Sprague-Dawley; Yohimbine | 2014 |
Mechanisms of morphine-venlafaxine interactions in diabetic neuropathic pain model.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Opioid; Animals; Brain Stem; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Synergism; Male; Morphine; Neuralgia; p-Chloroamphetamine; Pain Threshold; Physical Stimulation; Rats; Receptors, Opioid, mu; Serotonin Agents; Venlafaxine Hydrochloride; Yohimbine | 2015 |
Influence of morphine on medial prefrontal cortex alpha2 adrenergic system in passive avoidance learning in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Amnesia; Animals; Avoidance Learning; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Male; Microinjections; Morphine; Prefrontal Cortex; Rats; Receptors, Adrenergic, alpha-2; Yohimbine | 2015 |
Effects of cocaine history on postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dorsal Raphe Nucleus; Extinction, Psychological; Inhibitory Postsynaptic Potentials; Male; Morphine; Patch-Clamp Techniques; Rats, Sprague-Dawley; Receptors, GABA; Self Administration; Serotonergic Neurons; Stress, Psychological; Tissue Culture Techniques; Yohimbine | 2016 |