ym 511 has been researched along with letrozole in 4 studies
| Studies (ym 511) | Trials (ym 511) | Recent Studies (post-2010) (ym 511) | Studies (letrozole) | Trials (letrozole) | Recent Studies (post-2010) (letrozole) |
|---|---|---|---|---|---|
| 16 | 1 | 6 | 2,612 | 612 | 1,602 |
| Protein | Taxonomy | ym 511 (IC50) | letrozole (IC50) |
|---|---|---|---|
| Steryl-sulfatase | Homo sapiens (human) | 0.0009 | |
| Aromatase | Homo sapiens (human) | 0.009 | |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 2.62 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 1.42 | |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 0.0009 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Acharya, KR; Ho, YT; Lloyd, MD; Potter, BV; Purohit, A; Reed, MJ; Sutcliffe, OB; Thiyagarajan, N; Woo, LW | 1 |
| Bubert, C; Chander, SK; Mahon, MF; Potter, BV; Purohit, A; Reed, MJ; Smith, A; Sutcliffe, OB; Woo, LW | 1 |
| Potter, BV; Thomas, MP | 1 |
| Chander, SK; Humphreys, A; Potter, BV; Purohit, A; Reed, MJ; Woo, LW; Wood, PM | 1 |
4 other study(ies) available for ym 511 and letrozole
| Article | Year |
|---|---|
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.
Topics: Aromatase Inhibitors; Binding Sites; Carbonic Anhydrase II; Crystallization; Crystallography, X-Ray; Dimethyl Sulfoxide; Drug Stability; Enzyme Stability; Estrone; Humans; Ligands; Recombinant Proteins; Solvents; Steryl-Sulfatase | 2005 |
Dual aromatase-steroid sulfatase inhibitors.
Topics: Animals; Aromatase Inhibitors; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Models, Molecular; Protein Conformation; Rats; Rats, Wistar; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonamides; Triazoles | 2007 |
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosis; Estrone; Female; Humans; Male; Molecular Targeted Therapy; Prostatic Neoplasms; Steryl-Sulfatase; Sulfonic Acids; Tubulin Modulators | 2015 |
A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity.
Topics: Aromatase Inhibitors; Enzyme Inhibitors; Indicators and Reagents; Letrozole; Nitriles; Sulfatases; Triazoles | 2005 |