Page last updated: 2024-09-05

ym 511 and irosustat

ym 511 has been researched along with irosustat in 3 studies

Compound Research Comparison

Studies
(ym 511)
Trials
(ym 511)
Recent Studies (post-2010)
(ym 511)
Studies
(irosustat)
Trials
(irosustat)
Recent Studies (post-2010) (irosustat)
161668532

Protein Interaction Comparison

ProteinTaxonomyym 511 (IC50)irosustat (IC50)
Carbonic anhydrase 2Homo sapiens (human)0.018
Steryl-sulfataseHomo sapiens (human)0.0755
AromataseHomo sapiens (human)0.3
Amine oxidase [flavin-containing] A Rattus norvegicus (Norway rat)0.3

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bubert, C; Chander, SK; Grasso, A; Potter, BV; Purohit, A; Reed, MJ; Sutcliffe, OB; Woo, LW1
Acharya, KR; Ho, YT; Lloyd, MD; Potter, BV; Purohit, A; Reed, MJ; Sutcliffe, OB; Thiyagarajan, N; Woo, LW1
Bubert, C; Chander, SK; Mahon, MF; Potter, BV; Purohit, A; Reed, MJ; Smith, A; Sutcliffe, OB; Woo, LW1

Other Studies

3 other study(ies) available for ym 511 and irosustat

ArticleYear
First dual aromatase-steroid sulfatase inhibitors.
    Journal of medicinal chemistry, 2003, Jul-17, Volume: 46, Issue:15

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aromatase Inhibitors; Arylsulfatases; Cell Line; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Humans; Liver; Rats; Rats, Wistar; Steryl-Sulfatase

2003
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.
    Biochemistry, 2005, May-10, Volume: 44, Issue:18

    Topics: Aromatase Inhibitors; Binding Sites; Carbonic Anhydrase II; Crystallization; Crystallography, X-Ray; Dimethyl Sulfoxide; Drug Stability; Enzyme Stability; Estrone; Humans; Ligands; Recombinant Proteins; Solvents; Steryl-Sulfatase

2005
Dual aromatase-steroid sulfatase inhibitors.
    Journal of medicinal chemistry, 2007, Jul-26, Volume: 50, Issue:15

    Topics: Animals; Aromatase Inhibitors; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Models, Molecular; Protein Conformation; Rats; Rats, Wistar; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonamides; Triazoles

2007