ym 511 has been researched along with irosustat in 3 studies
| Studies (ym 511) | Trials (ym 511) | Recent Studies (post-2010) (ym 511) | Studies (irosustat) | Trials (irosustat) | Recent Studies (post-2010) (irosustat) |
|---|---|---|---|---|---|
| 16 | 1 | 6 | 68 | 5 | 32 |
| Protein | Taxonomy | ym 511 (IC50) | irosustat (IC50) |
|---|---|---|---|
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.018 | |
| Steryl-sulfatase | Homo sapiens (human) | 0.0755 | |
| Aromatase | Homo sapiens (human) | 0.3 | |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 0.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bubert, C; Chander, SK; Grasso, A; Potter, BV; Purohit, A; Reed, MJ; Sutcliffe, OB; Woo, LW | 1 |
| Acharya, KR; Ho, YT; Lloyd, MD; Potter, BV; Purohit, A; Reed, MJ; Sutcliffe, OB; Thiyagarajan, N; Woo, LW | 1 |
| Bubert, C; Chander, SK; Mahon, MF; Potter, BV; Purohit, A; Reed, MJ; Smith, A; Sutcliffe, OB; Woo, LW | 1 |
3 other study(ies) available for ym 511 and irosustat
| Article | Year |
|---|---|
First dual aromatase-steroid sulfatase inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aromatase Inhibitors; Arylsulfatases; Cell Line; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Humans; Liver; Rats; Rats, Wistar; Steryl-Sulfatase | 2003 |
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors.
Topics: Aromatase Inhibitors; Binding Sites; Carbonic Anhydrase II; Crystallization; Crystallography, X-Ray; Dimethyl Sulfoxide; Drug Stability; Enzyme Stability; Estrone; Humans; Ligands; Recombinant Proteins; Solvents; Steryl-Sulfatase | 2005 |
Dual aromatase-steroid sulfatase inhibitors.
Topics: Animals; Aromatase Inhibitors; Cell Line, Tumor; Crystallography, X-Ray; Female; Humans; Models, Molecular; Protein Conformation; Rats; Rats, Wistar; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonamides; Triazoles | 2007 |