ym 12617 and clonidine
ym 12617 has been researched along with clonidine in 5 studies
Compound Research Comparison
| Studies (ym 12617) | Trials (ym 12617) | Recent Studies (post-2010) (ym 12617) | Studies (clonidine) | Trials (clonidine) | Recent Studies (post-2010) (clonidine) |
|---|---|---|---|---|---|
| 32 | 2 | 6 | 13,692 | 2,044 | 1,394 |
Protein Interaction Comparison
| Protein | Taxonomy | ym 12617 (IC50) | clonidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.101 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0115 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.002 | |
| Nischarin | Rattus norvegicus (Norway rat) | 0.3662 |
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Abe, M; Ikeda, T; Matsumoto, M; Saito, H; Togashi, H; Yoshioka, M | 1 |
| Akimoto, Y; Fujiwara, M; Kurahashi, K; Sono, K | 1 |
| Honda, K; Miyata-Osawa, A; Shiono, K; Takenaka, T; Terai, M | 1 |
| Fujii, K; Kuriyama, H | 1 |
| Guarneri, L; Leonardi, A; Poggesi, E; Simonazzi, I; Taddei, C; Testa, R | 1 |
Other Studies
5 other study(ies) available for ym 12617 and clonidine
| Article | Year |
|---|---|
Central sympathoinhibitory action of a new type of alpha-1 adrenoceptor antagonist, YM-617, in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Electrophysiology; Heart Rate; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; RNA; Sulfonamides; Sympathetic Nervous System | 1990 |
Effects of specific alpha-adrenoceptive agents on extraneuronal uptake (uptake2) of isoproterenol in perfused rat heart.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Guanabenz; Isoproterenol; Male; Methoxamine; Myocardium; Neurons; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Sulfonamides; Tropolone | 1989 |
Studies on YM-12617: a selective and potent antagonist of postsynaptic alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Brain; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Pulmonary Artery; Quinoxalines; Rabbits; Rats; Receptors, Adrenergic, alpha; Sulfonamides; Tritium; Vas Deferens | 1985 |
Effects of YM-12617, an alpha adrenoceptor blocking agent, on electrical and mechanical properties of the guinea-pig mesenteric and pulmonary arteries.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Pulmonary Artery; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sulfonamides; Vasoconstriction | 1985 |
Mediation of noradrenaline-induced contractions of rat aorta by the alpha 1B-adrenoceptor subtype.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Computer Simulation; Hippocampus; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regression Analysis; Spiperone; Stereoisomerism; Sulfonamides | 1995 |