Protein | Taxonomy | ym 09151-2 (IC50) | chlorpromazine (IC50) |
Adenylate cyclase type 1 | Rattus norvegicus (Norway rat) | | 1.3 |
Spike glycoprotein | Betacoronavirus England 1 | | 9.51 |
Replicase polyprotein 1ab | Betacoronavirus England 1 | | 9.51 |
Solute carrier family 22 member 1 | Homo sapiens (human) | | 4.3 |
Transmembrane protease serine 2 | Homo sapiens (human) | | 9.51 |
Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | | 0.85 |
Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | | 0.85 |
Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | | 3.4 |
5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | | 0.0052 |
Potassium channel subfamily K member 2 | Homo sapiens (human) | | 2.7 |
Tyrosine-protein kinase Fyn | Homo sapiens (human) | | 8.68 |
Procathepsin L | Homo sapiens (human) | | 9.51 |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | | 0.019 |
Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | | 0.652 |
Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | | 0.149 |
Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | | 0.025 |
Alpha-2A adrenergic receptor | Homo sapiens (human) | | 0.352 |
Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | | 9.51 |
Replicase polyprotein 1ab | Human coronavirus 229E | | 9.51 |
Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | | 9.51 |
Calmodulin-1 | Homo sapiens (human) | | 7.63 |
Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | | 9.51 |
Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | | 0.083 |
Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | | 5.8275 |
D(2) dopamine receptor | Homo sapiens (human) | | 0.0142 |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | | 0.031 |
Alpha-2B adrenergic receptor | Homo sapiens (human) | | 0.026 |
Alpha-2C adrenergic receptor | Homo sapiens (human) | | 0.374 |
D | Rattus norvegicus (Norway rat) | | 0.1414 |
D(3) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0416 |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | | 4.685 |
Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | | 1.4791 |
D(2) dopamine receptor | Bos taurus (cattle) | | 0.5328 |
Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | | 0.206 |
D(1A) dopamine receptor | Homo sapiens (human) | | 0.225 |
D(4) dopamine receptor | Homo sapiens (human) | | 1.365 |
Adenylate cyclase type 3 | Rattus norvegicus (Norway rat) | | 1.3 |
Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | | 1.4791 |
Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | | 1.4791 |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | | 0.031 |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | | 0.019 |
Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | | 1.4791 |
Histamine H2 receptor | Homo sapiens (human) | | 2.626 |
Alpha-1D adrenergic receptor | Homo sapiens (human) | | 0.004 |
D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0416 |
Adenylate cyclase type 2 | Rattus norvegicus (Norway rat) | | 1.3 |
Adenylate cyclase type 4 | Rattus norvegicus (Norway rat) | | 1.3 |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | | 0.0036 |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | | 0.0052 |
5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | | 4.685 |
Trypanothione reductase | Trypanosoma cruzi | | 5.8 |
D(4) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0416 |
Sodium-dependent serotonin transporter | Homo sapiens (human) | | 0.0795 |
Melanocortin receptor 5 | Homo sapiens (human) | | 7.617 |
Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | | 4.5 |
Histamine H1 receptor | Homo sapiens (human) | | 0.0145 |
Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | | 1.3 |
D(3) dopamine receptor | Homo sapiens (human) | | 0.012 |
Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | | 4.3 |
Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | | 4.3 |
Adenylate cyclase type 8 | Rattus norvegicus (Norway rat) | | 1.3 |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | | 0.126 |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | | 0.031 |
5-hydroxytryptamine receptor 6 | Homo sapiens (human) | | 0.057 |
Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | | 9.51 |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | | 0.0365 |
Calmodulin | Bos taurus (cattle) | | 2.5 |
Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | | 1.3 |
Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | | 4.3 |
Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | | 3.4 |
Sodium-dependent dopamine transporter | Homo sapiens (human) | | 2.643 |
Adenylate cyclase type 6 | Rattus norvegicus (Norway rat) | | 1.3 |
Adenylate cyclase type 5 | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | | 0.85 |
Aldehyde oxidase | Homo sapiens (human) | | 0.57 |
Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | | 1.9602 |
Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | | 0.85 |
Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | | 0.85 |
Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | | 3.4 |
Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | | 3.4 |
Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | | 4.3 |
Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | | 0.85 |
Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | | 4.3 |
Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | | 1.3 |
Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | | 5.8275 |
Adenylyl cyclase 7 | Rattus norvegicus (Norway rat) | | 1.3 |
Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | | 0.85 |
Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | | 1.3 |
D | Bos taurus (cattle) | | 0.646 |
Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | | 4.3 |
Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | | 0.451 |
Angiotensin-converting enzyme 2 | Homo sapiens (human) | | 9.51 |
Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | | 4.3 |
Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | | 1.3 |
Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | | 4.3 |
Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | | 4.3 |
Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | | 4.3 |
Authors | Studies |
Kobayashi, T; Shimizu, H; Toru, M | 1 |
Chihara, K; Fujita, T; Kaji, H; Kita, T; Kodama, H; Minamitani, N | 1 |
Daus, FJ; Hansen, HA; Plantjé, JF; Stoof, JC | 1 |
Copolov, DL; Dean, B; Hussain, T; Pavey, G; Scarr, E | 1 |
Article | Year |
[The inhibition of dopamine D1 and D2 receptors in human putamen by antipsychotic drugs].Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1990, Volume: 10, Issue:2
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzamides; Benzazepines; Chlorpromazine; Depression, Chemical; Female; Haloperidol; Humans; In Vitro Techniques; Putamen; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride | 1990 |
Effect of various catecholamine antagonists on prolactin secretion in conscious male rabbits.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:1
Topics: Animals; Antipsychotic Agents; Benzamides; Catecholamines; Chlorpromazine; Consciousness; Haloperidol; Male; Metoprolol; Pimozide; Prazosin; Prolactin; Propranolol; Rabbits; Radioimmunoassay; Yohimbine | 1985 |
The effects of SCH 23390, YM 09151-2, (+)- and (-)-3-PPP and some classical neuroleptics on D-1 and D-2 receptors in rat neostriatum in vitro.European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Antipsychotic Agents; Aporphines; Benzamides; Benzazepines; Caudate Nucleus; Chlorpromazine; Clozapine; Flupenthixol; Haloperidol; In Vitro Techniques; Male; Piperidines; Potassium; Putamen; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1984 |
Extended treatment with typical and atypical antipsychotic drugs differential effects on the densities of dopamine D2-like and GABAA receptors in rat striatum.Life sciences, 2001, Aug-03, Volume: 69, Issue:11
Topics: Animals; Antipsychotic Agents; Benzamides; Benzazepines; Benzodiazepines; Chlorpromazine; Clozapine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Male; Muscimol; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, GABA-A | 2001 |