ym 022 has been researched along with omeprazole in 10 studies
| Studies (ym 022) | Trials (ym 022) | Recent Studies (post-2010) (ym 022) | Studies (omeprazole) | Trials (omeprazole) | Recent Studies (post-2010) (omeprazole) |
|---|---|---|---|---|---|
| 65 | 1 | 8 | 9,085 | 2,737 | 1,487 |
| Protein | Taxonomy | ym 022 (IC50) | omeprazole (IC50) |
|---|---|---|---|
| Mcl-1 | Homo sapiens (human) | 3.1448 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 0.28 | |
| Potassium-transporting ATPase alpha chain 1 | Homo sapiens (human) | 1.45 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 2.315 | |
| Potassium-transporting ATPase subunit beta | Homo sapiens (human) | 1.45 | |
| WD repeat-containing protein 5 | Homo sapiens (human) | 1.7 | |
| Glutathione S-transferase omega-1 | Homo sapiens (human) | 4.6 | |
| Histone-lysine N-methyltransferase 2A | Homo sapiens (human) | 1.7 | |
| Muscarinic acetylcholine receptor | Cavia porcellus (domestic guinea pig) | 3.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akuzawa, S; Ito, H; Kamato, T; Kobayashi-Uchida, A; Nagakura, Y; Nishida, A; Shishido, T; Takinami, Y; Yamano, M; Yuki, H | 1 |
| Fukamachi, H; Ichinose, M; Ishihama, S; Kakei, N; Kurokawa, K; Matsushima, M; Miki, K; Shimizu, M; Tatematsu, M; Yahagi, N | 1 |
| Akuzawa, S; Ito, H; Kamato, T; Kobayashi, A; Miyata, K; Nagakura, Y; Nishida, A; Takinami, Y; Yamano, M; Yuki, H | 1 |
| Ding, XQ; Håkanson, R; Lindström, E | 1 |
| Dimaline, R; Hamada, M; Kajiyama, G; Kamiyasu, T; Sumii, K; Sumii, M; Tari, A; Yonei, Y | 1 |
| Björkqvist, M; Chen, D; Ding, XQ; Håkanson, R; Kitano, M; Norlén, P; Zhao, CM | 1 |
| Björkqvist, M; Chen, D; de la Cour, CD; Gagnemo-Persson, C; Håkanson, R; Kitano, M; Norlén, P; Zhao, CM | 1 |
| Berry, D; Dockray, GJ; Pritchard, DM; Przemeck, SM; Steele, I; Varro, A; Wang, TC | 1 |
| Kanai, S; Miyasaka, K; Ohta, M; Suwa, Y; Tsutsumi, E | 1 |
| Choi, EK; Hayes, MM; Kang, AJ; Merchant, JL; Sundaresan, S | 1 |
10 other study(ies) available for ym 022 and omeprazole
| Article | Year |
|---|---|
Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
Topics: Animals; Benzodiazepines; Cell Count; Enterochromaffin Cells; Famotidine; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Omeprazole; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors | 1995 |
Effect of CCK-B/gastrin receptor antagonist on pepsinogen-producing cells during omeprazole treatment.
Topics: Animals; Benzodiazepines; Bromodeoxyuridine; Gastric Mucosa; Immunohistochemistry; Male; Omeprazole; Pepsinogens; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger; Stomach | 1995 |
YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Duodenal Ulcer; Epirizole; Ethanol; Famotidine; Gastric Acid; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Male; Omeprazole; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stomach Ulcer; Stress, Physiological | 1994 |
Cholecystokinin-B/gastrin receptor blockade suppresses the activity of rat stomach ECL cells.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Chromogranin A; Chromogranins; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Male; Omeprazole; Pancreatic Hormones; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; RNA, Messenger; RNA, Ribosomal, 18S; Stomach | 1997 |
Role of gastrin/CCK-B receptor in the regulation of gastric acid secretion in rat.
Topics: Actins; Animals; Benzodiazepines; Enzyme Inhibitors; Gastric Acid; Gastrins; Gene Expression; H(+)-K(+)-Exchanging ATPase; Histamine Release; Histidine Decarboxylase; Hormone Antagonists; Male; Omeprazole; Parietal Cells, Gastric; Proton Pump Inhibitors; Rats; Rats, Wistar; Receptors, Cholecystokinin; RNA, Messenger | 1997 |
Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Chromogranin A; Cytoplasmic Granules; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Immunohistochemistry; Male; Microscopy, Electron; Omeprazole; Pancreatic Hormones; Parietal Cells, Gastric; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors | 2000 |
Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Digestive System; Drug Interactions; Gastrins; Hormone Antagonists; Hyperplasia; Hypertrophy; Male; Omeprazole; Pancreas; Parietal Cells, Gastric; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin | 2001 |
Hypergastrinemia increases gastric epithelial susceptibility to apoptosis.
Topics: Animals; Anti-Ulcer Agents; Apoptosis; Benzodiazepines; Cells, Cultured; Disease Susceptibility; Gamma Rays; Gastric Mucosa; Gastrins; Helicobacter pylori; Humans; Mice; Mice, Transgenic; Omeprazole; Receptor, Cholecystokinin B; Stomach Neoplasms | 2008 |
Stimulatory effect of N-methyltyramine, a congener of beer, on pancreatic secretion in conscious rats.
Topics: Amylases; Animals; Atropine; Beer; Benzodiazepines; Gastrins; Infusions, Intravenous; Injections; Male; Omeprazole; Pancreas; Pancreatic Juice; Proglumide; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Solutions; Stomach; Tyramine | 2010 |
Deletion of
Topics: Adenocarcinoma; Adult; Animals; Benzodiazepines; Carcinogenesis; Carcinoid Tumor; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Female; Gastrins; Gene Deletion; Hormone Antagonists; Hormones; Humans; Male; Mice; Mice, Transgenic; Omeprazole; Phosphorylation; Proto-Oncogene Proteins; Proton Pump Inhibitors; Receptor, Cholecystokinin B; RNA, Messenger; Signal Transduction; Somatostatin; Stomach Neoplasms | 2017 |