ym 022 has been researched along with histamine in 14 studies
| Studies (ym 022) | Trials (ym 022) | Recent Studies (post-2010) (ym 022) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 65 | 1 | 8 | 37,718 | 1,372 | 3,457 |
| Protein | Taxonomy | ym 022 (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akuzawa, S; Ito, H; Kamato, T; Kobayashi-Uchida, A; Nagakura, Y; Nishida, A; Shishido, T; Takinami, Y; Yamano, M; Yuki, H | 1 |
| Akuzawa, S; Ito, H; Kamato, T; Katuyama, Y; Kobayashi, A; Miyata, K; Nishida, A; Tsutsumi, R; Yamano, M; Yuki, H | 1 |
| Akuzawa, S; Miyata, K; Nishida, A; Takemoto, Y; Uchida-Kobayashi, A | 1 |
| Ding, XQ; Håkanson, R | 1 |
| Akuzawa, S; Ito, H; Miyake, A; Miyata, K; Nishida, A; Takemoto, Y; Takinami, Y; Yuki, H | 1 |
| Ding, XQ; Håkanson, R; Lindström, E | 2 |
| Ding, XQ; Håkanson, R; Kitano, M | 1 |
| Ding, XQ; Håkanson, R; Kitano, M; Lindström, E; Norlén, P | 1 |
| Ding, XQ; Håkanson, R; Lindström, E; Norlén, P | 1 |
| Björkqvist, M; Chen, D; Ding, XQ; Håkanson, R; Kitano, M; Norlén, P; Zhao, CM | 1 |
| Håkanson, R; Kitano, M; Norlén, P | 1 |
| Aihara, T; Chen, D; Fujishita, T; Furutani, K; Kanatani, K; Matsui, M; Nakamura, E; Okabe, S; Taketo, MM | 1 |
| Imatake, K; Matsui, T; Moriyama, M | 1 |
1 review(s) available for ym 022 and histamine
| Article | Year |
|---|---|
CCK2 receptor antagonists: pharmacological tools to study the gastrin-ECL cell-parietal cell axis.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Chromogranin A; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Humans; Indoles; Pancreatic Hormones; Parietal Cells, Gastric; Phenylurea Compounds; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stomach | 1999 |
13 other study(ies) available for ym 022 and histamine
| Article | Year |
|---|---|
Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
Topics: Animals; Benzodiazepines; Cell Count; Enterochromaffin Cells; Famotidine; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Omeprazole; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors | 1995 |
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Indoles; Male; Meglumine; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1994 |
Comparative evaluation of the role of endogenous gastrin in basal acid secretion in conscious rats provided with chronic fistula and pylorus ligation.
Topics: Animals; Atropine; Benzodiazepines; Chronic Disease; Famotidine; Gastric Acid; Gastric Fistula; Gastrins; Histamine; Ligation; Male; Parasympathetic Nervous System; Pylorus; Rats; Rats, Sprague-Dawley | 1996 |
Effect of cholecystokinin-B/gastrin receptor blockade on gastric acid secretion in conscious rats.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Vagus Nerve | 1996 |
YM022, a potent and selective gastrin/CCK-B receptor antagonist, inhibits peptone meal-induced gastric acid secretion in Heidenhain pouch dogs.
Topics: Animals; Atropine; Benzodiazepines; Benzodiazepinones; Devazepide; Dogs; Dose-Response Relationship, Drug; Eating; Famotidine; Gastric Acid; Histamine; Histamine H2 Antagonists; Hormone Antagonists; Male; Methacholine Chloride; Muscarinic Antagonists; Pentagastrin; Peptones; Phenylurea Compounds; Receptors, Cholecystokinin; Sincalide; Stomach | 1997 |
Cholecystokinin-B/gastrin receptor blockade suppresses the activity of rat stomach ECL cells.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Chromogranin A; Chromogranins; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Male; Omeprazole; Pancreatic Hormones; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; RNA, Messenger; RNA, Ribosomal, 18S; Stomach | 1997 |
Time-course of deactivation of rat stomach ECL cells following cholecystokinin B/gastrin receptor blockade.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Body Weight; Chromogranin A; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Pancreatic Hormones; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger; Stomach; Time Factors | 1997 |
Sustained cholecystokinin-B/gastrin receptor blockade does not impair basal or histamine-stimulated acid secretion in chronic gastric fistula rats.
Topics: Animals; Benzodiazepines; Cholecystokinin; Gastric Acid; Gastric Fistula; Gastrins; Histamine; Hormone Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin | 1998 |
Reversibility of cholecystokinin-B/gastrin receptor blockade: a study of the gastrin-ECL cell axis in the rat.
Topics: Animals; Benzodiazepines; Chromogranin A; Chromogranins; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Male; Pancreatic Hormones; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger | 1999 |
Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Chromogranin A; Cytoplasmic Granules; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Immunohistochemistry; Male; Microscopy, Electron; Omeprazole; Pancreatic Hormones; Parietal Cells, Gastric; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors | 2000 |
Gastric submucosal microdialysis: a method to study gastrin- and food-evoked mobilization of ECL-cell histamine in conscious rats.
Topics: Animals; Benzodiazepines; Chromogranin A; Enterochromaffin-like Cells; Enzyme Inhibitors; Fluorescent Antibody Technique; Food; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Methylhistidines; Microdialysis; Pancreatic Hormones; Rats; Rats, Sprague-Dawley; Time Factors; Vagotomy, Proximal Gastric | 2000 |
Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice.
Topics: Animals; Benzodiazepines; Calcium; Cell Division; Enterochromaffin Cells; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Muscarinic M3 | 2003 |
The effect and mechanism of action of capsaicin on gastric acid output.
Topics: Animals; Benzodiazepines; Bethanechol; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastrins; Histamine; Histamine H2 Antagonists; Hormone Antagonists; In Vitro Techniques; Male; Muscarinic Agonists; Rats; Rats, Wistar; Somatostatin; Stomach; Vagus Nerve | 2009 |