Page last updated: 2024-09-03

ym 022 and gastrins

ym 022 has been researched along with gastrins in 25 studies

Compound Research Comparison

Studies
(ym 022)
Trials
(ym 022)
Recent Studies (post-2010)
(ym 022)
Studies
(gastrins)
Trials
(gastrins)
Recent Studies (post-2010) (gastrins)
651812,748659786

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (44.00)18.2507
2000's11 (44.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Akuzawa, S; Ito, H; Kamato, T; Kobayashi-Uchida, A; Nagakura, Y; Nishida, A; Shishido, T; Takinami, Y; Yamano, M; Yuki, H1
Akuzawa, S; Miyata, K; Nishida, A; Takemoto, Y; Uchida-Kobayashi, A1
Ding, XQ; Håkanson, R1
Ding, XQ; Håkanson, R; Lindström, E2
Dimaline, R; Hamada, M; Kajiyama, G; Kamiyasu, T; Sumii, K; Sumii, M; Tari, A; Yonei, Y1
Ding, XQ; Håkanson, R; Kitano, M1
Alchepo, B; Attoub, S; Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L1
Ding, XQ; Håkanson, R; Kitano, M; Lindström, E; Norlén, P1
Ding, XQ; Håkanson, R; Lindström, E; Norlén, P1
Ahlman, H; Kölby, L; Modlin, IM; Nilsson, O; Theodorsson, E; Wängberg, B1
Björkqvist, M; Chen, D; Ding, XQ; Håkanson, R; Kitano, M; Norlén, P; Zhao, CM1
Håkanson, R; Kitano, M; Norlén, P1
Ding, XQ; Håkanson, R; Kitano, M; Nakamura, S; Norlén, P1
Capellà, G; Clavé, P; Farré, R; González, AA; Monés, J1
Björkqvist, M; Chen, D; de la Cour, CD; Gagnemo-Persson, C; Håkanson, R; Kitano, M; Norlén, P; Zhao, CM1
Aihara, T; Chen, D; Fujishita, T; Furutani, K; Kanatani, K; Matsui, M; Nakamura, E; Okabe, S; Taketo, MM1
Awan, A; Clarke, PA; Harris, JC; Jankowski, J; Watson, SA1
Abdalla, SI; Fitzgerald, RC; Lao-Sirieix, P; Lovat, LB; Novelli, MR; Sanderson, IR1
Chao, C; Davey, RA; Goluszko, E; Hellmich, MR; Ives, KL; Kolokoltsov, AA; Townsend, CM1
Berry, D; Dockray, GJ; Pritchard, DM; Przemeck, SM; Steele, I; Varro, A; Wang, TC1
Imatake, K; Matsui, T; Moriyama, M1
Kanai, S; Miyasaka, K; Ohta, M; Suwa, Y; Tsutsumi, E1
Choi, EK; Hayes, MM; Kang, AJ; Merchant, JL; Sundaresan, S1
Boyce, M; Burkitt, MD; Dodd, S; Duckworth, CA; Exarchou, K; Fang, Y; Hall, N; Howes, N; Lloyd, KA; Moore, AR; Oxvig, C; Papoutsopoulou, S; Parsons, BN; Pritchard, DM; Rainbow, L; Varro, A1

Reviews

1 review(s) available for ym 022 and gastrins

ArticleYear
CCK2 receptor antagonists: pharmacological tools to study the gastrin-ECL cell-parietal cell axis.
    Regulatory peptides, 1999, Mar-17, Volume: 80, Issue:1-2

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Chromogranin A; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Humans; Indoles; Pancreatic Hormones; Parietal Cells, Gastric; Phenylurea Compounds; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stomach

1999

Trials

1 trial(s) available for ym 022 and gastrins

ArticleYear
Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors.
    Cellular and molecular gastroenterology and hepatology, 2020, Volume: 10, Issue:1

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Cell Line, Tumor; Disease Models, Animal; Gastric Mucosa; Gastrins; Gene Knockdown Techniques; Humans; Mice; Mice, Transgenic; Neuroendocrine Tumors; Organoids; Phenylurea Compounds; Pregnancy-Associated Plasma Protein-A; Primary Cell Culture; Receptor, Cholecystokinin B; Stomach Neoplasms; Treatment Outcome

2020

Other Studies

23 other study(ies) available for ym 022 and gastrins

ArticleYear
Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
    The American journal of physiology, 1995, Volume: 269, Issue:5 Pt 1

    Topics: Animals; Benzodiazepines; Cell Count; Enterochromaffin Cells; Famotidine; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Omeprazole; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors

1995
Comparative evaluation of the role of endogenous gastrin in basal acid secretion in conscious rats provided with chronic fistula and pylorus ligation.
    Japanese journal of pharmacology, 1996, Volume: 71, Issue:3

    Topics: Animals; Atropine; Benzodiazepines; Chronic Disease; Famotidine; Gastric Acid; Gastric Fistula; Gastrins; Histamine; Ligation; Male; Parasympathetic Nervous System; Pylorus; Rats; Rats, Sprague-Dawley

1996
Effect of cholecystokinin-B/gastrin receptor blockade on gastric acid secretion in conscious rats.
    Pharmacology & toxicology, 1996, Volume: 79, Issue:6

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Vagus Nerve

1996
Cholecystokinin-B/gastrin receptor blockade suppresses the activity of rat stomach ECL cells.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Chromogranin A; Chromogranins; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Male; Omeprazole; Pancreatic Hormones; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; RNA, Messenger; RNA, Ribosomal, 18S; Stomach

1997
Time-course of deactivation of rat stomach ECL cells following cholecystokinin B/gastrin receptor blockade.
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Body Weight; Chromogranin A; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Pancreatic Hormones; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger; Stomach; Time Factors

1997
Role of gastrin/CCK-B receptor in the regulation of gastric acid secretion in rat.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:9

    Topics: Actins; Animals; Benzodiazepines; Enzyme Inhibitors; Gastric Acid; Gastrins; Gene Expression; H(+)-K(+)-Exchanging ATPase; Histamine Release; Histidine Decarboxylase; Hormone Antagonists; Male; Omeprazole; Parietal Cells, Gastric; Proton Pump Inhibitors; Rats; Rats, Wistar; Receptors, Cholecystokinin; RNA, Messenger

1997
Sustained cholecystokinin-B/gastrin receptor blockade does not impair basal or histamine-stimulated acid secretion in chronic gastric fistula rats.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:4

    Topics: Animals; Benzodiazepines; Cholecystokinin; Gastric Acid; Gastric Fistula; Gastrins; Histamine; Hormone Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin

1998
YM022, a highly potent and selective CCKB antagonist inhibiting gastric acid secretion in the rat, the cat and isolated rabbit glands.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:3

    Topics: Aminopyrine; Animals; Benzodiazepines; Benzodiazepinones; Cats; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Acid; Gastric Fistula; Gastric Mucosa; Gastrins; Hormone Antagonists; Indoles; Male; Meglumine; Phenylurea Compounds; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin

1998
Reversibility of cholecystokinin-B/gastrin receptor blockade: a study of the gastrin-ECL cell axis in the rat.
    Pharmacology & toxicology, 1999, Volume: 84, Issue:4

    Topics: Animals; Benzodiazepines; Chromogranin A; Chromogranins; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Male; Pancreatic Hormones; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger

1999
Altered influence of CCK-B/gastrin receptors on HDC expression in ECL cells after neoplastic transformation.
    Regulatory peptides, 1999, Dec-23, Volume: 85, Issue:2-3

    Topics: Animals; Benzodiazepines; Carcinoid Tumor; Cell Transformation, Neoplastic; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Gene Expression; Histamine H2 Antagonists; Histidine Decarboxylase; Hormone Antagonists; Humans; Muridae; Receptors, Cholecystokinin; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Triazoles

1999
Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study.
    Cell and tissue research, 2000, Volume: 299, Issue:1

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Chromogranin A; Cytoplasmic Granules; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Immunohistochemistry; Male; Microscopy, Electron; Omeprazole; Pancreatic Hormones; Parietal Cells, Gastric; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors

2000
Gastric submucosal microdialysis: a method to study gastrin- and food-evoked mobilization of ECL-cell histamine in conscious rats.
    Regulatory peptides, 2000, Jan-29, Volume: 86, Issue:1-3

    Topics: Animals; Benzodiazepines; Chromogranin A; Enterochromaffin-like Cells; Enzyme Inhibitors; Fluorescent Antibody Technique; Food; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Methylhistidines; Microdialysis; Pancreatic Hormones; Rats; Rats, Sprague-Dawley; Time Factors; Vagotomy, Proximal Gastric

2000
Long-lasting cholecystokinin(2) receptor blockade after a single subcutaneous injection of YF476 or YM022.
    British journal of pharmacology, 2000, Volume: 130, Issue:3

    Topics: Administration, Oral; Animals; Benzodiazepines; Benzodiazepinones; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrins; Histidine Decarboxylase; Hormone Antagonists; Injections, Subcutaneous; Male; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Weight Gain

2000
Pharmacological and molecular characterization of muscular cholecystokinin receptors in the human lower oesophageal sphincter.
    Neurogastroenterology and motility, 2000, Volume: 12, Issue:6

    Topics: Adult; Aged; Benzodiazepines; Benzodiazepinones; Esophagogastric Junction; Female; Gastric Emptying; Gastrins; Gastrointestinal Agents; Gene Expression; Hormone Antagonists; Humans; In Vitro Techniques; Indoleacetic Acids; Male; Middle Aged; Phenylurea Compounds; Proglumide; Receptors, Cholecystokinin; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sincalide; Thiazoles

2000
Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:4

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Digestive System; Drug Interactions; Gastrins; Hormone Antagonists; Hyperplasia; Hypertrophy; Male; Omeprazole; Pancreas; Parietal Cells, Gastric; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin

2001
Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice.
    Gastroenterology, 2003, Volume: 125, Issue:6

    Topics: Animals; Benzodiazepines; Calcium; Cell Division; Enterochromaffin Cells; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Muscarinic M3

2003
An antiapoptotic role for gastrin and the gastrin/CCK-2 receptor in Barrett's esophagus.
    Cancer research, 2004, Mar-15, Volume: 64, Issue:6

    Topics: Adenocarcinoma; Apoptosis; Barrett Esophagus; Benzodiazepines; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophagus; Gastrins; Hormone Antagonists; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Cholecystokinin B; Tumor Cells, Cultured

2004
Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jul-15, Volume: 10, Issue:14

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Benzodiazepines; Blotting, Western; Case-Control Studies; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Gastrins; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Longitudinal Studies; Male; Membrane Proteins; Middle Aged; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptor, Cholecystokinin B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured

2004
SRC regulates constitutive internalization and rapid resensitization of a cholecystokinin 2 receptor splice variant.
    The Journal of biological chemistry, 2005, Sep-30, Volume: 280, Issue:39

    Topics: Alternative Splicing; Amino Acid Sequence; Benzodiazepines; Calcium; Carbocyanines; Cell Line; Cell Membrane; Clone Cells; Fluorescent Dyes; Gastrins; Genetic Variation; Green Fluorescent Proteins; Hormone Antagonists; Humans; Introns; Kinetics; Microscopy, Confocal; Models, Biological; Protein Structure, Tertiary; Receptor, Cholecystokinin B; Retroviridae; src-Family Kinases; Transduction, Genetic

2005
Hypergastrinemia increases gastric epithelial susceptibility to apoptosis.
    Regulatory peptides, 2008, Feb-07, Volume: 146, Issue:1-3

    Topics: Animals; Anti-Ulcer Agents; Apoptosis; Benzodiazepines; Cells, Cultured; Disease Susceptibility; Gamma Rays; Gastric Mucosa; Gastrins; Helicobacter pylori; Humans; Mice; Mice, Transgenic; Omeprazole; Receptor, Cholecystokinin B; Stomach Neoplasms

2008
The effect and mechanism of action of capsaicin on gastric acid output.
    Journal of gastroenterology, 2009, Volume: 44, Issue:5

    Topics: Animals; Benzodiazepines; Bethanechol; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastrins; Histamine; Histamine H2 Antagonists; Hormone Antagonists; In Vitro Techniques; Male; Muscarinic Agonists; Rats; Rats, Wistar; Somatostatin; Stomach; Vagus Nerve

2009
Stimulatory effect of N-methyltyramine, a congener of beer, on pancreatic secretion in conscious rats.
    Alcoholism, clinical and experimental research, 2010, Volume: 34 Suppl 1

    Topics: Amylases; Animals; Atropine; Beer; Benzodiazepines; Gastrins; Infusions, Intravenous; Injections; Male; Omeprazole; Pancreas; Pancreatic Juice; Proglumide; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Solutions; Stomach; Tyramine

2010
Deletion of
    Gut, 2017, Volume: 66, Issue:6

    Topics: Adenocarcinoma; Adult; Animals; Benzodiazepines; Carcinogenesis; Carcinoid Tumor; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Female; Gastrins; Gene Deletion; Hormone Antagonists; Hormones; Humans; Male; Mice; Mice, Transgenic; Omeprazole; Phosphorylation; Proto-Oncogene Proteins; Proton Pump Inhibitors; Receptor, Cholecystokinin B; RNA, Messenger; Signal Transduction; Somatostatin; Stomach Neoplasms

2017
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