ym 022 and gastrins
ym 022 has been researched along with gastrins in 25 studies
Compound Research Comparison
| Studies (ym 022) | Trials (ym 022) | Recent Studies (post-2010) (ym 022) | Studies (gastrins) | Trials (gastrins) | Recent Studies (post-2010) (gastrins) |
|---|---|---|---|---|---|
| 65 | 1 | 8 | 12,748 | 659 | 786 |
Research
Studies (25)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (44.00) | 18.2507 |
| 2000's | 11 (44.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Akuzawa, S; Ito, H; Kamato, T; Kobayashi-Uchida, A; Nagakura, Y; Nishida, A; Shishido, T; Takinami, Y; Yamano, M; Yuki, H | 1 |
| Akuzawa, S; Miyata, K; Nishida, A; Takemoto, Y; Uchida-Kobayashi, A | 1 |
| Ding, XQ; Håkanson, R | 1 |
| Ding, XQ; Håkanson, R; Lindström, E | 2 |
| Dimaline, R; Hamada, M; Kajiyama, G; Kamiyasu, T; Sumii, K; Sumii, M; Tari, A; Yonei, Y | 1 |
| Ding, XQ; Håkanson, R; Kitano, M | 1 |
| Alchepo, B; Attoub, S; Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L | 1 |
| Ding, XQ; Håkanson, R; Kitano, M; Lindström, E; Norlén, P | 1 |
| Ding, XQ; Håkanson, R; Lindström, E; Norlén, P | 1 |
| Ahlman, H; Kölby, L; Modlin, IM; Nilsson, O; Theodorsson, E; Wängberg, B | 1 |
| Björkqvist, M; Chen, D; Ding, XQ; Håkanson, R; Kitano, M; Norlén, P; Zhao, CM | 1 |
| Håkanson, R; Kitano, M; Norlén, P | 1 |
| Ding, XQ; Håkanson, R; Kitano, M; Nakamura, S; Norlén, P | 1 |
| Capellà, G; Clavé, P; Farré, R; González, AA; Monés, J | 1 |
| Björkqvist, M; Chen, D; de la Cour, CD; Gagnemo-Persson, C; Håkanson, R; Kitano, M; Norlén, P; Zhao, CM | 1 |
| Aihara, T; Chen, D; Fujishita, T; Furutani, K; Kanatani, K; Matsui, M; Nakamura, E; Okabe, S; Taketo, MM | 1 |
| Awan, A; Clarke, PA; Harris, JC; Jankowski, J; Watson, SA | 1 |
| Abdalla, SI; Fitzgerald, RC; Lao-Sirieix, P; Lovat, LB; Novelli, MR; Sanderson, IR | 1 |
| Chao, C; Davey, RA; Goluszko, E; Hellmich, MR; Ives, KL; Kolokoltsov, AA; Townsend, CM | 1 |
| Berry, D; Dockray, GJ; Pritchard, DM; Przemeck, SM; Steele, I; Varro, A; Wang, TC | 1 |
| Imatake, K; Matsui, T; Moriyama, M | 1 |
| Kanai, S; Miyasaka, K; Ohta, M; Suwa, Y; Tsutsumi, E | 1 |
| Choi, EK; Hayes, MM; Kang, AJ; Merchant, JL; Sundaresan, S | 1 |
| Boyce, M; Burkitt, MD; Dodd, S; Duckworth, CA; Exarchou, K; Fang, Y; Hall, N; Howes, N; Lloyd, KA; Moore, AR; Oxvig, C; Papoutsopoulou, S; Parsons, BN; Pritchard, DM; Rainbow, L; Varro, A | 1 |
Reviews
1 review(s) available for ym 022 and gastrins
| Article | Year |
|---|---|
CCK2 receptor antagonists: pharmacological tools to study the gastrin-ECL cell-parietal cell axis.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Chromogranin A; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Humans; Indoles; Pancreatic Hormones; Parietal Cells, Gastric; Phenylurea Compounds; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stomach | 1999 |
Trials
1 trial(s) available for ym 022 and gastrins
| Article | Year |
|---|---|
Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Cell Line, Tumor; Disease Models, Animal; Gastric Mucosa; Gastrins; Gene Knockdown Techniques; Humans; Mice; Mice, Transgenic; Neuroendocrine Tumors; Organoids; Phenylurea Compounds; Pregnancy-Associated Plasma Protein-A; Primary Cell Culture; Receptor, Cholecystokinin B; Stomach Neoplasms; Treatment Outcome | 2020 |
Other Studies
23 other study(ies) available for ym 022 and gastrins
| Article | Year |
|---|---|
Gastrin receptor antagonist YM022 prevents hypersecretion after long-term acid suppression.
Topics: Animals; Benzodiazepines; Cell Count; Enterochromaffin Cells; Famotidine; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Omeprazole; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors | 1995 |
Comparative evaluation of the role of endogenous gastrin in basal acid secretion in conscious rats provided with chronic fistula and pylorus ligation.
Topics: Animals; Atropine; Benzodiazepines; Chronic Disease; Famotidine; Gastric Acid; Gastric Fistula; Gastrins; Histamine; Ligation; Male; Parasympathetic Nervous System; Pylorus; Rats; Rats, Sprague-Dawley | 1996 |
Effect of cholecystokinin-B/gastrin receptor blockade on gastric acid secretion in conscious rats.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Vagus Nerve | 1996 |
Cholecystokinin-B/gastrin receptor blockade suppresses the activity of rat stomach ECL cells.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Chromogranin A; Chromogranins; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Male; Omeprazole; Pancreatic Hormones; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; RNA, Messenger; RNA, Ribosomal, 18S; Stomach | 1997 |
Time-course of deactivation of rat stomach ECL cells following cholecystokinin B/gastrin receptor blockade.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Body Weight; Chromogranin A; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Pancreatic Hormones; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger; Stomach; Time Factors | 1997 |
Role of gastrin/CCK-B receptor in the regulation of gastric acid secretion in rat.
Topics: Actins; Animals; Benzodiazepines; Enzyme Inhibitors; Gastric Acid; Gastrins; Gene Expression; H(+)-K(+)-Exchanging ATPase; Histamine Release; Histidine Decarboxylase; Hormone Antagonists; Male; Omeprazole; Parietal Cells, Gastric; Proton Pump Inhibitors; Rats; Rats, Wistar; Receptors, Cholecystokinin; RNA, Messenger | 1997 |
Sustained cholecystokinin-B/gastrin receptor blockade does not impair basal or histamine-stimulated acid secretion in chronic gastric fistula rats.
Topics: Animals; Benzodiazepines; Cholecystokinin; Gastric Acid; Gastric Fistula; Gastrins; Histamine; Hormone Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin | 1998 |
YM022, a highly potent and selective CCKB antagonist inhibiting gastric acid secretion in the rat, the cat and isolated rabbit glands.
Topics: Aminopyrine; Animals; Benzodiazepines; Benzodiazepinones; Cats; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Acid; Gastric Fistula; Gastric Mucosa; Gastrins; Hormone Antagonists; Indoles; Male; Meglumine; Phenylurea Compounds; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin | 1998 |
Reversibility of cholecystokinin-B/gastrin receptor blockade: a study of the gastrin-ECL cell axis in the rat.
Topics: Animals; Benzodiazepines; Chromogranin A; Chromogranins; Gastric Mucosa; Gastrins; Histamine; Histidine Decarboxylase; Male; Pancreatic Hormones; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger | 1999 |
Altered influence of CCK-B/gastrin receptors on HDC expression in ECL cells after neoplastic transformation.
Topics: Animals; Benzodiazepines; Carcinoid Tumor; Cell Transformation, Neoplastic; Enterochromaffin Cells; Gastric Mucosa; Gastrins; Gene Expression; Histamine H2 Antagonists; Histidine Decarboxylase; Hormone Antagonists; Humans; Muridae; Receptors, Cholecystokinin; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Triazoles | 1999 |
Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Chromogranin A; Cytoplasmic Granules; Gastrins; Histamine; Histidine Decarboxylase; Hormone Antagonists; Immunohistochemistry; Male; Microscopy, Electron; Omeprazole; Pancreatic Hormones; Parietal Cells, Gastric; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Time Factors | 2000 |
Gastric submucosal microdialysis: a method to study gastrin- and food-evoked mobilization of ECL-cell histamine in conscious rats.
Topics: Animals; Benzodiazepines; Chromogranin A; Enterochromaffin-like Cells; Enzyme Inhibitors; Fluorescent Antibody Technique; Food; Gastric Mucosa; Gastrins; Histamine; Hormone Antagonists; Male; Methylhistidines; Microdialysis; Pancreatic Hormones; Rats; Rats, Sprague-Dawley; Time Factors; Vagotomy, Proximal Gastric | 2000 |
Long-lasting cholecystokinin(2) receptor blockade after a single subcutaneous injection of YF476 or YM022.
Topics: Administration, Oral; Animals; Benzodiazepines; Benzodiazepinones; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Gastrins; Histidine Decarboxylase; Hormone Antagonists; Injections, Subcutaneous; Male; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Weight Gain | 2000 |
Pharmacological and molecular characterization of muscular cholecystokinin receptors in the human lower oesophageal sphincter.
Topics: Adult; Aged; Benzodiazepines; Benzodiazepinones; Esophagogastric Junction; Female; Gastric Emptying; Gastrins; Gastrointestinal Agents; Gene Expression; Hormone Antagonists; Humans; In Vitro Techniques; Indoleacetic Acids; Male; Middle Aged; Phenylurea Compounds; Proglumide; Receptors, Cholecystokinin; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sincalide; Thiazoles | 2000 |
Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Digestive System; Drug Interactions; Gastrins; Hormone Antagonists; Hyperplasia; Hypertrophy; Male; Omeprazole; Pancreas; Parietal Cells, Gastric; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin | 2001 |
Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor knockout mice.
Topics: Animals; Benzodiazepines; Calcium; Cell Division; Enterochromaffin Cells; Female; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Muscarinic M3 | 2003 |
An antiapoptotic role for gastrin and the gastrin/CCK-2 receptor in Barrett's esophagus.
Topics: Adenocarcinoma; Apoptosis; Barrett Esophagus; Benzodiazepines; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophagus; Gastrins; Hormone Antagonists; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Cholecystokinin B; Tumor Cells, Cultured | 2004 |
Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Benzodiazepines; Blotting, Western; Case-Control Studies; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Gastrins; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Longitudinal Studies; Male; Membrane Proteins; Middle Aged; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptor, Cholecystokinin B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tumor Cells, Cultured | 2004 |
SRC regulates constitutive internalization and rapid resensitization of a cholecystokinin 2 receptor splice variant.
Topics: Alternative Splicing; Amino Acid Sequence; Benzodiazepines; Calcium; Carbocyanines; Cell Line; Cell Membrane; Clone Cells; Fluorescent Dyes; Gastrins; Genetic Variation; Green Fluorescent Proteins; Hormone Antagonists; Humans; Introns; Kinetics; Microscopy, Confocal; Models, Biological; Protein Structure, Tertiary; Receptor, Cholecystokinin B; Retroviridae; src-Family Kinases; Transduction, Genetic | 2005 |
Hypergastrinemia increases gastric epithelial susceptibility to apoptosis.
Topics: Animals; Anti-Ulcer Agents; Apoptosis; Benzodiazepines; Cells, Cultured; Disease Susceptibility; Gamma Rays; Gastric Mucosa; Gastrins; Helicobacter pylori; Humans; Mice; Mice, Transgenic; Omeprazole; Receptor, Cholecystokinin B; Stomach Neoplasms | 2008 |
The effect and mechanism of action of capsaicin on gastric acid output.
Topics: Animals; Benzodiazepines; Bethanechol; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastrins; Histamine; Histamine H2 Antagonists; Hormone Antagonists; In Vitro Techniques; Male; Muscarinic Agonists; Rats; Rats, Wistar; Somatostatin; Stomach; Vagus Nerve | 2009 |
Stimulatory effect of N-methyltyramine, a congener of beer, on pancreatic secretion in conscious rats.
Topics: Amylases; Animals; Atropine; Beer; Benzodiazepines; Gastrins; Infusions, Intravenous; Injections; Male; Omeprazole; Pancreas; Pancreatic Juice; Proglumide; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Solutions; Stomach; Tyramine | 2010 |
Deletion of
Topics: Adenocarcinoma; Adult; Animals; Benzodiazepines; Carcinogenesis; Carcinoid Tumor; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Female; Gastrins; Gene Deletion; Hormone Antagonists; Hormones; Humans; Male; Mice; Mice, Transgenic; Omeprazole; Phosphorylation; Proto-Oncogene Proteins; Proton Pump Inhibitors; Receptor, Cholecystokinin B; RNA, Messenger; Signal Transduction; Somatostatin; Stomach Neoplasms | 2017 |