Page last updated: 2024-09-04

yh 439 and benzo(a)pyrene

yh 439 has been researched along with benzo(a)pyrene in 3 studies

Compound Research Comparison

Studies
(yh 439)
Trials
(yh 439)
Recent Studies (post-2010)
(yh 439)
Studies
(benzo(a)pyrene)
Trials
(benzo(a)pyrene)
Recent Studies (post-2010) (benzo(a)pyrene)
21027,311172,154

Protein Interaction Comparison

ProteinTaxonomyyh 439 (IC50)benzo(a)pyrene (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.04
Amine oxidase [flavin-containing] AHomo sapiens (human)5.972

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Antonchick, AP; Brause, A; Dötsch, L; Flegel, A; Flegel, J; Hoffmann, JE; Janning, P; Jia, ZJ; Krzyzanowski, A; Lian, Y; Metz, M; Moura-Alves, P; Rastinejad, F; Reich, A; Schade, D; Scheel, R; Schneidewind, T; Schulte, B; Shaaban, S; Sievers, S; Stender, ID; Strohmann, C; Waldmann, H; Wesseler, F; Xue, G; Zhang, M; Ziegler, S1
Lee, JW; Shlyankevich, M; Surh, YJ; Yoo, JK1
Kim, SG; Lee, JW; Liem, A; Miller, JA; Surh, YJ1

Other Studies

3 other study(ies) available for yh 439 and benzo(a)pyrene

ArticleYear
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.
    Journal of medicinal chemistry, 2022, 12-22, Volume: 65, Issue:24

    Topics: Cell Differentiation; Hedgehog Proteins; Osteoblasts; Receptors, Aryl Hydrocarbon; Signal Transduction

2022
Inhibition of covalent DNA binding and mutagenicity of benzo[a]pyrene by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2-yl) carbamoyl]acetate (YH439), a novel hepatoprotective agent.
    Mutation research, 1996, Apr-06, Volume: 367, Issue:4

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Benzo(a)pyrene; Biotransformation; DNA; DNA Adducts; Liver; Microsomes, Liver; Molecular Structure; Mutagenicity Tests; Mutagens; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Thiazoles

1996
Inhibitory effects of isopropyl-2-(1,3-dithietane-2-ylidene)-2- [N-(4-methylthiazol-2-yl)carbamoyl]acetate (YH439) on benzo[a]pyrene-induced skin carcinogenesis and micronucleated reticulocyte formation in mice.
    Mutation research, 1999, Jan-25, Volume: 423, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Crosses, Genetic; Female; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Micronuclei, Chromosome-Defective; Micronucleus Tests; Papilloma; Reticulocytes; Skin Neoplasms; Thiazoles

1999