yh 439 has been researched along with benzo(a)pyrene in 3 studies
| Studies (yh 439) | Trials (yh 439) | Recent Studies (post-2010) (yh 439) | Studies (benzo(a)pyrene) | Trials (benzo(a)pyrene) | Recent Studies (post-2010) (benzo(a)pyrene) |
|---|---|---|---|---|---|
| 21 | 0 | 2 | 7,311 | 17 | 2,154 |
| Protein | Taxonomy | yh 439 (IC50) | benzo(a)pyrene (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.04 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 5.972 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Antonchick, AP; Brause, A; Dötsch, L; Flegel, A; Flegel, J; Hoffmann, JE; Janning, P; Jia, ZJ; Krzyzanowski, A; Lian, Y; Metz, M; Moura-Alves, P; Rastinejad, F; Reich, A; Schade, D; Scheel, R; Schneidewind, T; Schulte, B; Shaaban, S; Sievers, S; Stender, ID; Strohmann, C; Waldmann, H; Wesseler, F; Xue, G; Zhang, M; Ziegler, S | 1 |
| Lee, JW; Shlyankevich, M; Surh, YJ; Yoo, JK | 1 |
| Kim, SG; Lee, JW; Liem, A; Miller, JA; Surh, YJ | 1 |
3 other study(ies) available for yh 439 and benzo(a)pyrene
| Article | Year |
|---|---|
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.
Topics: Cell Differentiation; Hedgehog Proteins; Osteoblasts; Receptors, Aryl Hydrocarbon; Signal Transduction | 2022 |
Inhibition of covalent DNA binding and mutagenicity of benzo[a]pyrene by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2-yl) carbamoyl]acetate (YH439), a novel hepatoprotective agent.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Benzo(a)pyrene; Biotransformation; DNA; DNA Adducts; Liver; Microsomes, Liver; Molecular Structure; Mutagenicity Tests; Mutagens; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Thiazoles | 1996 |
Inhibitory effects of isopropyl-2-(1,3-dithietane-2-ylidene)-2- [N-(4-methylthiazol-2-yl)carbamoyl]acetate (YH439) on benzo[a]pyrene-induced skin carcinogenesis and micronucleated reticulocyte formation in mice.
Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Crosses, Genetic; Female; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Micronuclei, Chromosome-Defective; Micronucleus Tests; Papilloma; Reticulocytes; Skin Neoplasms; Thiazoles | 1999 |