Compounds > yh 1885
Page last updated: 2024-09-05

yh 1885 and indomethacin

yh 1885 has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(yh 1885)		Trials
(yh 1885)		Recent Studies (post-2010)
(yh 1885)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
3042229,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyyh 1885 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Chung, JW; Hahm, KB; Kim, JH; Kim, YJ; Kwon, KA; Lim, YJ; Ock, CY1
Dial, EJ; Graham, DY; Lichtenberger, LM; Lim, YJ; Phan, TM1
Hahm, KB; Han, YM; Her, S; Kim, MS; Park, JM; Park, YJ1

Other Studies

3 other study(ies) available for yh 1885 and indomethacin

ArticleYear
Acid pump antagonist-provoked HSP27 dephosphorylation and accentuation rescues stomach from indomethacin-induced damages.
    Journal of digestive diseases, 2011, Volume: 12, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Culture Techniques; Electrophoresis, Gel, Two-Dimensional; Gastric Mucosa; HSP27 Heat-Shock Proteins; Indomethacin; Pyrimidinones; Rats; Stomach; Tetrahydroisoquinolines

2011
In vitro and in vivo protection against indomethacin-induced small intestinal injury by proton pump inhibitors, acid pump antagonists, or indomethacin-phosphatidylcholine.
    Digestion, 2012, Volume: 86, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Survival; Cells, Cultured; Epithelial Cells; Gastrointestinal Hemorrhage; Indomethacin; Intestinal Mucosa; Intestine, Small; Lansoprazole; Male; Omeprazole; Phosphatidylcholines; Proton Pump Inhibitors; Pyrimidinones; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

2012
Revaprazan prevented indomethacin-induced intestinal damages by enhancing tight junction related mechanisms.
    Biochemical pharmacology, 2020, Volume: 182

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Humans; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Proton Pump Inhibitors; Pyrimidinones; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Tight Junctions

2020