Page last updated: 2024-09-03

y 590 and rolipram

y 590 has been researched along with rolipram in 1 studies

Compound Research Comparison

Studies (y 590)	Trials (y 590)	Recent Studies (post-2010) (y 590)	Studies (rolipram)	Trials (rolipram)	Recent Studies (post-2010) (rolipram)
5	0	0	1,604	17	401

Protein Interaction Comparison

Protein	Taxonomy	rolipram (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	1.2233
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	Homo sapiens (human)	1.2233
Retina-specific copper amine oxidase	Homo sapiens (human)	0.0003
cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	1.0975
3',5'-cyclic-AMP phosphodiesterase	Sus scrofa (pig)	3.63
Renin	Homo sapiens (human)	3.5
Tumor necrosis factor	Homo sapiens (human)	0.35
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Rattus norvegicus (Norway rat)	0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Rattus norvegicus (Norway rat)	0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Rattus norvegicus (Norway rat)	0.8447
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)	1.1942
Sodium-dependent serotonin transporter	Rattus norvegicus (Norway rat)	0.095
Delta-type opioid receptor	Mus musculus (house mouse)	1.5
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	1.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Rattus norvegicus (Norway rat)	0.7287
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Homo sapiens (human)	0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	1.1005
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)	1.61
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	1.0794
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	0.835
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	Homo sapiens (human)	0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	Homo sapiens (human)	0.835
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	Homo sapiens (human)	0.835

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bristol, JA; Cain, MH; Weishaar, RE	1

Reviews

1 review(s) available for y 590 and rolipram

Article	Year
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity. Journal of medicinal chemistry, 1985, Volume: 28, Issue:5 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity	1985

Article

Year

A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.

Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity

1985