y 27632 has been researched along with transforming growth factor beta in 26 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (transforming growth factor beta) | Trials (transforming growth factor beta) | Recent Studies (post-2010) (transforming growth factor beta) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 49,119 | 560 | 17,610 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Egashira, K; Inoue, S; Kaibuchi, K; Kataoka, C; Kitamoto, S; Koyanagi, M; Ni, W; Shimokawa, H; Takemoto, M; Takeshita, A; Usui, M | 1 |
| Aspenström, P; Edlund, S; Heldin, CH; Landström, M | 1 |
| Arii, S; Imamura, M; Mori, A; Murata, T | 1 |
| Grigoriadis, AE; Harmey, D; Lax, AJ; Nobes, CD; Stenbeck, G | 1 |
| Clements, RT; Keller, RS; Minnear, FL; Singer, HA; Vincent, PA | 1 |
| Kobayashi, N; Matsuoka, H; Mita, S; Nakano, S; Yoshida, K | 1 |
| Briones, VR; Chen, S; Crawford, M; Day, RM; Jose, PA; Leader, JE; Lechleider, RJ | 1 |
| Barnett, JV; Desgrosellier, JS; Galper, JB; Georgescu, SP; Papageorge, AG; Park, HJ; Ward, SM; Zhuang, X | 1 |
| Camerer, E; Chambers, RC; Davis, GE; Jenkins, RG; Laurent, GJ; Matthay, MA; Scotton, CJ; Sheppard, D; Su, G; Su, X | 1 |
| Fafet, P; Maudelonde, T; Rebouissou, C; Vignais, ML | 1 |
| Akhmetshina, A; Dees, C; Distler, JH; Distler, O; Pileckyte, M; Schett, G; Spriewald, BM; Szucs, G; Zwerina, J | 1 |
| Goppelt-Struebe, M; Keller, C; Kroening, S; Stix, J; Streiff, C | 1 |
| Abo, Y; Ichikawa, H; Nakata, N; Sasaki, K; Shirasawa, S; Tomotsune, D; Yokoyama, T; Yoshie, S; Yue, F | 1 |
| Janshoff, A; Schneider, D | 1 |
| Ampe, C; Bakkali, K; Colaert, N; Debeir, O; Decaestecker, C; Doll, T; Gevaert, K; Hinz, B; Jonckheere, V; Lambrechts, A; Lemaistre, M; Müller, M; Staes, A; Timmerman, E; Tondeleir, D; Vandamme, D; Vandekerckhove, J; Waterschoot, D | 1 |
| Harata, A; Ihara, S; Matsuzaki, T; Nishikawa, A | 1 |
| Dulin, N; Kach, J; Kregel, S; Ngam, C; Sandbo, N; Torr, E | 1 |
| Barker, TH; Dysart, MM; Galvis, BR; Russell, AG | 1 |
| Beuerman, RW; Kadaba, A; Mehta, JS; Myint, HH; Tian, D; Yam, GH; Yusoff, NZ; Zhou, L | 1 |
| Biondini, M; Camonis, J; Duclos, G; Meyer-Schaller, N; Parrini, MC; Silberzan, P | 1 |
| Bansal, MB; Chamroonkul, N | 1 |
| Iida, H; Kojima, A; Kozawa, O; Nakashima, D; Tachi, J; Tanabe, K | 1 |
| Ibrahim, DG; Iwata, W; Kiuchi, Y; Ko, JA; Okumichi, H | 1 |
| Babaahmadi-Rezaei, H; Little, PJ; Niayesh-Mehr, R; Seif, F; Zamanpour, M | 1 |
| Idiris, A; Kumagai, H; Miyagi, Y; Miyazaki, K; Okamoto, R; Togo, S | 1 |
| Liao, SL; Wang, CC; Wang, SH; Wei, YH; Yang, CH | 1 |
1 review(s) available for y 27632 and transforming growth factor beta
| Article | Year |
|---|---|
Antifibrotics in liver disease: are we getting closer to clinical use?
Topics: Adaptive Immunity; Adipokines; Amides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Apoptosis; Cannabinoid Receptor Antagonists; Cell Communication; Cell Transdifferentiation; Cellular Senescence; Endothelin Receptor Antagonists; Enzyme Inhibitors; Epigenesis, Genetic; Epithelial Cells; Extracellular Matrix; Galectins; Hepatic Stellate Cells; Humans; Immunity, Innate; Integrins; Liver Cirrhosis; NF-kappa B; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Receptors, Cannabinoid; Receptors, CCR; Renin-Angiotensin System; Signal Transduction; Toll-Like Receptors; Transforming Growth Factor beta | 2019 |
25 other study(ies) available for y 27632 and transforming growth factor beta
| Article | Year |
|---|---|
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats.
Topics: Actins; Amides; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Chemokine CCL2; Coronary Vessels; Enzyme Inhibitors; Hydralazine; Immunohistochemistry; Inflammation; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Muscle, Smooth; Myosins; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; rho-Associated Kinases; RNA, Messenger; Superoxide Dismutase; Tetrazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA.
Topics: Actins; Amides; Animals; cdc42 GTP-Binding Protein; Cell Surface Extensions; Cytoskeleton; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; rac1 GTP-Binding Protein; Rats; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Smad4 Protein; Stress Fibers; Trans-Activators; Transforming Growth Factor beta; Tumor Cells, Cultured | 2002 |
Therapeutic significance of Y-27632, a Rho-kinase inhibitor, on the established liver fibrosis.
Topics: Actins; Amides; Animals; Carbon Tetrachloride; Enzyme Inhibitors; Infusion Pumps, Implantable; Infusions, Parenteral; Intracellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis, Experimental; Male; Models, Animal; Myocytes, Smooth Muscle; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Sodium-Calcium Exchanger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Regulation of osteoblast differentiation by Pasteurella multocida toxin (PMT): a role for Rho GTPase in bone formation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; ADP Ribose Transferases; Amides; Animals; Bacterial Proteins; Bacterial Toxins; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Botulinum Toxins; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Mice; Osteoblasts; Osteogenesis; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Skull; Transforming Growth Factor beta | 2004 |
RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability.
Topics: ADP Ribose Transferases; Amides; Animals; Botulinum Toxins; Capillary Permeability; Cattle; Cells, Cultured; Cytoskeleton; Endothelium, Vascular; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Myosin Light Chains; Phosphorylation; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Cardioprotective mechanisms of Rho-kinase inhibition associated with eNOS and oxidative stress-LOX-1 pathway in Dahl salt-sensitive hypertensive rats.
Topics: Amides; Animals; Collagen Type I; Collagen Type III; Coronary Vessels; Enzyme Inhibitors; Fibronectins; Hypertension; Intracellular Signaling Peptides and Proteins; Male; NADPH Oxidases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred Dahl; Receptors, LDL; Receptors, Oxidized LDL; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Transcription Factor RelA; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
RhoA modulates Smad signaling during transforming growth factor-beta-induced smooth muscle differentiation.
Topics: Amides; Animals; Cell Differentiation; Cell Line; Mice; Mice, Inbred C3H; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Pyridines; rhoA GTP-Binding Protein; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta | 2006 |
Transforming growth factor beta regulates the expression of the M2 muscarinic receptor in atrial myocytes via an effect on RhoA and p190RhoGAP.
Topics: Amides; Animals; Carrier Proteins; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Gene Expression Regulation; Heart Atria; Muscle Cells; Promoter Regions, Genetic; Pyridines; Receptor, Muscarinic M2; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta | 2006 |
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Bleomycin; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Humans; Integrins; Intracellular Signaling Peptides and Proteins; Lung; Mice; Mice, Knockout; Peptides; Protein Serine-Threonine Kinases; Pulmonary Edema; Pyridines; Receptor, PAR-1; Respiratory Distress Syndrome; rho-Associated Kinases; rhoA GTP-Binding Protein; Thrombin; Transforming Growth Factor beta | 2006 |
Opposite effects of transforming growth factor-beta activation and rho-associated kinase inhibition on human trophoblast migration in a reconstituted placental-endometrial coculture system.
Topics: Adult; Amides; Cell Adhesion; Cell Movement; Cells, Cultured; Coculture Techniques; Decidua; Endometrium; Enzyme Inhibitors; Female; Humans; Placenta; Pregnancy; Pyridines; rho-Associated Kinases; Signal Transduction; Transforming Growth Factor beta; Trophoblasts | 2008 |
Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts.
Topics: Adult; Aged; Amides; Case-Control Studies; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Extracellular Matrix; Female; Fibroblasts; Humans; Male; Matrix Metalloproteinases; Middle Aged; Platelet-Derived Growth Factor; Pyridines; rho-Associated Kinases; Scleroderma, Systemic; Skin; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta | 2008 |
Matrix-independent stimulation of human tubular epithelial cell migration by Rho kinase inhibitors.
Topics: Actins; Amides; Cadherins; Cell Line; Cell Movement; Cell Shape; Epithelial Cells; Extracellular Matrix; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Kidney Tubules, Proximal; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Transforming Growth Factor beta | 2010 |
Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells.
Topics: Amides; Apoptosis; Benzamides; Caspase 10; Caspase 3; Caspase 8; Cell Line; Cell Survival; Cryopreservation; Cryoprotective Agents; Dioxoles; Embryonic Stem Cells; Humans; Imidazoles; Interleukin-1beta; p38 Mitogen-Activated Protein Kinases; Pyridines; rho-Associated Kinases; Transforming Growth Factor beta | 2012 |
Inhibition of actin dynamics during epithelial-to-mesenchymal transition.
Topics: Actins; Amides; Animals; Cell Line; Cell Shape; Dielectric Spectroscopy; Epithelial-Mesenchymal Transition; Heterocyclic Compounds, 4 or More Rings; Mice; Microscopy, Fluorescence; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Transforming Growth Factor beta | 2012 |
Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity.
Topics: Actins; Amides; Animals; Blotting, Western; Cell Adhesion; Cell Movement; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation, Developmental; Mice; Mice, Knockout; Protein Isoforms; Proteomics; Pseudopodia; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; Transforming Growth Factor beta | 2012 |
The cell sorting process of Xenopus gastrula cells involves the acto-myosin system and TGF-β signaling.
Topics: Actomyosin; Amides; Aminoquinolines; Animals; Body Patterning; Cartilage; Cell Aggregation; Cell Movement; Embryonic Development; Gastrula; Mesoderm; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Xenopus | 2013 |
Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2.
Topics: Adaptor Proteins, Signal Transducing; Amides; Anilides; Benzamides; Cell Differentiation; Cells, Cultured; Colchicine; DNA-Binding Proteins; Enzyme Inhibitors; Formins; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Microtubules; Myofibroblasts; Oncogene Proteins, Fusion; Paclitaxel; Protein Transport; Pyridines; Serum Response Factor; Smad Proteins; Stress Fibers; Trans-Activators; Transforming Growth Factor beta; Tubulin Modulators | 2013 |
Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor beta.
Topics: Alveolar Epithelial Cells; Amides; Cell Line; Cell Survival; Humans; Intracellular Space; Particulate Matter; Phenotype; Pyridines; Reactive Oxygen Species; rho-Associated Kinases; Stress, Physiological; Transforming Growth Factor beta | 2014 |
Ex Vivo Propagation of Human Corneal Stromal "Activated Keratocytes" for Tissue Engineering.
Topics: Adult; Amides; Amnion; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Corneal Stroma; Female; Gene Expression Regulation; Humans; Insulin-Like Growth Factor I; Keratinocytes; Keratoconus; Male; Microscopy, Fluorescence; Middle Aged; Proteoglycans; Proteome; Pyridines; Real-Time Polymerase Chain Reaction; Smad2 Protein; Smad3 Protein; Tandem Mass Spectrometry; Tissue Engineering; Transforming Growth Factor beta | 2015 |
RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1.
Topics: Amides; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Microscopy, Atomic Force; Pyridines; rac1 GTP-Binding Protein; ral GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta | 2015 |
Limitation by Rho-kinase and Rac of transforming growth factor-β-induced interleukin-6 release from astrocytes.
Topics: Amides; Aminoquinolines; Animals; Astrocytes; Interleukin-6; Mice; Phosphorylation; Pyridines; Pyrimidines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta | 2019 |
An in vitro study of scarring formation mediated by human Tenon fibroblasts: Effect of Y-27632, a Rho kinase inhibitor.
Topics: Amides; Cicatrix; Collagen; Fibroblasts; Humans; Latanoprost; Pyridines; rho-Associated Kinases; Signal Transduction; Tenon Capsule; Timolol; Transforming Growth Factor beta | 2019 |
Endothelin-1 increases CHSY-1 expression in aortic endothelial cells via transactivation of transforming growth factor β type I receptor induced by type B receptor endothelin-1.
Topics: Amides; Animals; Aorta; Blotting, Western; Cattle; Cells, Cultured; Cytochalasin D; Endothelial Cells; Endothelin-1; N-Acetylgalactosaminyltransferases; Oligopeptides; Phosphorylation; Piperidines; Pyridines; Receptor, Endothelin B; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; rho-Associated Kinases; Time Factors; Transcriptional Activation; Transforming Growth Factor beta | 2019 |
Collective cancer cell invasion in contact with fibroblasts through integrin-α5β1/fibronectin interaction in collagen matrix.
Topics: A549 Cells; Adenocarcinoma; Amides; Benzamides; Cancer-Associated Fibroblasts; Cell Adhesion; Cell Line, Tumor; Cell Movement; Chromones; Collagen; Colonic Neoplasms; Connective Tissue; Dioxoles; Epidermal Growth Factor; Fibroblasts; Fibronectins; Humans; Immunohistochemistry; Integrin alpha5beta1; MCF-7 Cells; Morpholines; Neoplasm Invasiveness; Pyridines; Spheroids, Cellular; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2020 |
Simvastatin and ROCK Inhibitor Y-27632 Inhibit Myofibroblast Differentiation of Graves' Ophthalmopathy-Derived Orbital Fibroblasts
Topics: Adult; Amides; Cell Differentiation; Female; Fibrosis; Graves Ophthalmopathy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; MAP Kinase Signaling System; Middle Aged; Myofibroblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Primary Cell Culture; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Simvastatin; Transforming Growth Factor beta | 2020 |