Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and tadalafil

y 27632 has been researched along with tadalafil in 2 studies

Compound Research Comparison

Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010)
(y 27632)		Studies
(tadalafil)		Trials
(tadalafil)		Recent Studies (post-2010) (tadalafil)
1,92438911,7423921,089

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)tadalafil (IC50)
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)0.0012
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.0012
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.0012
Chain A, cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.0012
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.0704
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaHomo sapiens (human)2.928
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)3.0704
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.5153
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaBos taurus (cattle)5.1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alphaBos taurus (cattle)4.05
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alphaHomo sapiens (human)2.928
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'Bos taurus (cattle)5.1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)2.928
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaBos taurus (cattle)5.1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit betaBos taurus (cattle)5.1
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)9.2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit betaHomo sapiens (human)2.928
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'Homo sapiens (human)2.507
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.0704
Synaptic vesicular amine transporterRattus norvegicus (Norway rat)0.012
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)4.6028
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)9.2
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)4.6028
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)3.0704
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammaHomo sapiens (human)2.928
cGMP-specific 3',5'-cyclic phosphodiesteraseBos taurus (cattle)0.0075
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit deltaBos taurus (cattle)5.1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)0.8575
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)3.0704
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)3.0704

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Carini, M; Cellai, I; Comeglio, P; Filippi, S; Gacci, M; Maggi, M; Maneschi, E; Morelli, A; Sarchielli, E; Vannelli, GB; Vignozzi, L1

Other Studies

2 other study(ies) available for y 27632 and tadalafil

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Tadalafil effect on metabolic syndrome-associated bladder alterations: an experimental study in a rabbit model.
    The journal of sexual medicine, 2014, Volume: 11, Issue:5

    Topics: Amides; Animals; Carbolines; Diet, High-Fat; Enzyme Inhibitors; Male; Metabolic Syndrome; Muscle Contraction; Muscle, Smooth; Pyridines; Rabbits; rho-Associated Kinases; Signal Transduction; Tadalafil; Up-Regulation; Urinary Bladder Diseases; Urological Agents

2014