Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and su 6656

y 27632 has been researched along with su 6656 in 7 studies

Compound Research Comparison

Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010)
(y 27632)		Studies
(su 6656)		Trials
(su 6656)		Recent Studies (post-2010) (su 6656)
1,9243891154073

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)su 6656 (IC50)
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)0.1
Proto-oncogene tyrosine-protein kinase LCK Mus musculus (house mouse)0.15
Tyrosine-protein kinase FynHomo sapiens (human)0.17
Tyrosine-protein kinase YesHomo sapiens (human)0.02
Tyrosine-protein kinase LynHomo sapiens (human)0.13
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.77
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.1765
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)8.7
Serine/threonine-protein kinase 3Homo sapiens (human)0.11
Serine/threonine-protein kinase BRSK2Homo sapiens (human)0.1
Aurora kinase BHomo sapiens (human)0.019
ALK tyrosine kinase receptorHomo sapiens (human)0.85
Aurora kinase CHomo sapiens (human)0.017

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Aaronson, PI; Drndarski, S; Knock, GA; Shaifta, Y; Snetkov, VA; Ward, JP1
Aaronson, PI; Becker, S; Connolly, M; Drndarski, S; Knock, GA; Noah, A; Pourmahram, GE; Shaifta, Y; Snetkov, VA; Ward, JP1
Avanzi, MP; Chen, A; He, W; Mitchell, WB1

Other Studies

7 other study(ies) available for y 27632 and su 6656

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery.
    Cardiovascular research, 2008, Dec-01, Volume: 80, Issue:3

    Topics: Amides; Animals; Calcium; Enzyme Inhibitors; Hypoxia; Indoles; Male; Models, Animal; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phosphorylation; Pulmonary Artery; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Sulfonamides; Vasoconstriction

2008
Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization.
    Free radical biology & medicine, 2009, Mar-01, Volume: 46, Issue:5

    Topics: Active Transport, Cell Nucleus; Amides; Aminoquinolines; Animals; Bronchoconstriction; Calcium Signaling; Guanylate Cyclase; Hypertension, Pulmonary; Indoles; Male; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphorylation; Protein Phosphatase 1; Pulmonary Artery; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Sulfonamides; Superoxides

2009
Optimizing megakaryocyte polyploidization by targeting multiple pathways of cytokinesis.
    Transfusion, 2012, Volume: 52, Issue:11

    Topics: Actin Cytoskeleton; Amides; Benzamides; Blood Platelets; Cells, Cultured; Cytokinesis; Enzyme Inhibitors; Fetal Blood; Humans; Indoles; Megakaryocytes; Microtubules; Niacinamide; Ploidies; Polyploidy; Pyridines; Quinazolines; Signal Transduction; src-Family Kinases; Sulfonamides; Vitamin B Complex

2012