| Protein | Taxonomy | y 27632 (IC50) | staurosporine (IC50) |
|---|
| Chain A, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | | 0.015 |
| Chain B, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | | 0.015 |
| Chain A, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | | 0.015 |
| Chain A, Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | | 0.0558 |
| Chain A, Tyrosine-protein kinase SYK | Homo sapiens (human) | | 0.012 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | | 0.01 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | | 0.01 |
| Chain X, Proto-oncogene tyrosine-protein kinase Fyn | Homo sapiens (human) | | 0.0048 |
| Chain A, Serine/threonine-protein kinase TAO2 | Rattus norvegicus (Norway rat) | | 3 |
| epidermal growth factor receptor isoform a precursor | Homo sapiens (human) | | 0.4467 |
| Serine/threonine-protein kinase Sgk1 | Homo sapiens (human) | | 0.01 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | | 0.0549 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | | 0.0083 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | | 0.0029 |
| Citron Rho-interacting kinase | Homo sapiens (human) | | 0.749 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | | 0.9255 |
| Telomerase reverse transcriptase | Homo sapiens (human) | | 6.9517 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | | 0.1772 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | | 0.5561 |
| Aurora kinase A | Homo sapiens (human) | | 0.0087 |
| Cyclin-G-associated kinase | Homo sapiens (human) | | 0.011 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | | 0.267 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | | 0.1265 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | | 0.1161 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | | 0.4137 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | | 0.0072 |
| Death-associated protein kinase 3 | Homo sapiens (human) | | 0.0026 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | | 0.0565 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.356 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 | Homo sapiens (human) | | 0.0231 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | | 0.003 |
| Cyclin-T1 | Homo sapiens (human) | | 0.0118 |
| Cyclin-T2 | Homo sapiens (human) | | 0.0038 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | | 0.0016 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | | 0.0045 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | | 0.0096 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | | 0.1246 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | | 0.0011 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | | 0.0071 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | | 0.2385 |
| Cyclin-K | Homo sapiens (human) | | 0.0948 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | | 0.0003 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | | 0.0258 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | | 0.008 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | | 0.1446 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | | 0.1145 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | | 0.0107 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | | 0.2829 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | | 0.0005 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | | 0.013 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | | 0.0132 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | | 0.0212 |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | | 0.011 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | | 0.0812 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | | 0.1233 |
| Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | | 0.0063 |
| Epidermal growth factor receptor | Homo sapiens (human) | | 0.083 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | | 0.1281 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | | 0.0713 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | | 0.2403 |
| Protein kinase C gamma type | Homo sapiens (human) | | 0.1167 |
| Platelet-derived growth factor receptor beta | Mus musculus (house mouse) | | 0.002 |
| Protein kinase C alpha type | Rattus norvegicus (Norway rat) | | 0.2327 |
| Protein kinase C beta type | Homo sapiens (human) | | 0.0684 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | | 0.056 |
| Insulin receptor | Homo sapiens (human) | | 0.0706 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | | 0.1784 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | | 0.0929 |
| Retinoblastoma-associated protein | Homo sapiens (human) | | 0.066 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | | 0.0075 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | | 0.0039 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | | 0.1269 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | | 0.0029 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | | 0.0012 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | | 0.0021 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | | 0.5534 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | | 0.1917 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | | 0.0025 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | | 0.0004 |
| Protein kinase C delta type | Rattus norvegicus (Norway rat) | | 0.274 |
| Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | | 0.274 |
| Protein kinase C zeta type | Rattus norvegicus (Norway rat) | | 0.274 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | | 0.3707 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | | 0.0009 |
| Cytochrome P450 2D6 | Homo sapiens (human) | | 0.0002 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | | 0.0412 |
| Breakpoint cluster region protein | Homo sapiens (human) | | 0.0945 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Rattus norvegicus (Norway rat) | | 0.059 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | | 0.0216 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | | 0.0699 |
| Cyclin-dependent kinase 1 | Mus musculus (house mouse) | | 0.008 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | | 0.0429 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | | 0.3642 |
| Acyl-CoA desaturase 1 | Mus musculus (house mouse) | | 3.4 |
| Insulin receptor-related protein | Homo sapiens (human) | | 0.0113 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | | 0.0088 |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | | 0.003 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | | 4 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | | 0.0107 |
| Insulin receptor | Mus musculus (house mouse) | | 0.2 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | | 0.0004 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | | 0.0007 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | | 0.0008 |
| Protein kinase C alpha type | Homo sapiens (human) | | 0.0655 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | | 0.0115 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | | 0.0149 |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | | 0.011 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | | 0.1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | | 0.0025 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | | 2.0215 |
| Cyclin-A2 | Homo sapiens (human) | | 0.009 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | | 0.01 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | | 0.0257 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | | 0.0947 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | | 0.0504 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | | 0.0106 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | | 0.17 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | | 0.0554 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | | 0.0137 |
| Cyclin-O | Homo sapiens (human) | | 0.0015 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | | 0.0148 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | | 0.0007 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | | 0.004 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | | 0.028 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | | 0.0355 |
| Protein kinase C eta type | Homo sapiens (human) | | 0.1165 |
| Cyclin-C | Homo sapiens (human) | | 0.0105 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | | 0.0108 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | | 0.0073 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | | 1.1595 |
| Platelet-derived growth factor receptor alpha | Mus musculus (house mouse) | | 0.002 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | | 4.6724 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | | 0.0004 |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | | 0.055 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | | 2.6853 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | | 0.1257 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | | 0.0347 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | | 0.1061 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | | 0.1191 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | | 0.0173 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | | 0.0137 |
| G1/S-specific cyclin-D3 | Homo sapiens (human) | | 0.055 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | | 0.0131 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | | 0.1848 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | | 0.4119 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | | 0.0914 |
| Kinesin-1 heavy chain | Homo sapiens (human) | | 0.0015 |
| G protein-coupled receptor kinase 5 | Homo sapiens (human) | | 0.0489 |
| Hexokinase-4 | Homo sapiens (human) | | 0.0006 |
| Beta-adrenergic receptor kinase 2 | Homo sapiens (human) | | 0.856 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | | 0.0146 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | | 0.1791 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | | 0.026 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | | 0.0014 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | | 4.288 |
| Activin receptor type-1B | Homo sapiens (human) | | 9.118 |
| TGF-beta receptor type-1 | Homo sapiens (human) | | 2.2823 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | | 0.85 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | | 0.2071 |
| Protein kinase C iota type | Homo sapiens (human) | | 0.1739 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | | 0.442 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | | 0.0338 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | | 0.0203 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | | 0.0505 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | | 0.0108 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | | 0.0473 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | | 0.0175 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | | 0.0057 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | | 1.1067 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | | 2.0555 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | | 0.863 |
| Phosphorylase b kinase regulatory subunit alpha, liver isoform | Homo sapiens (human) | | 0.0005 |
| Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform | Homo sapiens (human) | | 0.0005 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | | 0.0099 |
| Casein kinase I isoform alpha | Homo sapiens (human) | | 3.412 |
| Casein kinase I isoform delta | Homo sapiens (human) | | 1.4 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | | 9 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | | 0.735 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | | 0.0105 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | | 1.4 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | | 0.0108 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | | 0.6508 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | | 0.92 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | | 0.0103 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | | 0.0435 |
| D(1A) dopamine receptor | Sus scrofa (pig) | | 0.001 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | | 0.2793 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | | 0.0474 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | | 0.0011 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | | 0.0377 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | | 0.0002 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | | 0.0046 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | | 0.0014 |
| Cyclin-H | Homo sapiens (human) | | 0.2793 |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | | 0.1216 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | | 1.7683 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | | 0.0851 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | | 0.0084 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | | 0.0036 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | | 0.4397 |
| Death-associated protein kinase 1 | Homo sapiens (human) | | 0.0101 |
| LIM domain kinase 1 | Homo sapiens (human) | | 0.0026 |
| LIM domain kinase 2 | Homo sapiens (human) | | 0.0956 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | | 0.4512 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | | 0.0731 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | | 1.1354 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | | 1.2855 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | | 0.0159 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | | 0.1869 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | | 0.0694 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | | 0.0105 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | | 0.0009 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum K1 | | 0.24 |
| Protein kinase C gamma type | Rattus norvegicus (Norway rat) | | 0.2168 |
| Casein kinase II subunit beta | Homo sapiens (human) | | 3.4 |
| Casein kinase II subunit alpha | Homo sapiens (human) | | 3.4723 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | | 0.2029 |
| SRSF protein kinase 2 | Homo sapiens (human) | | 0.206 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | | 1.9467 |
| Cyclin-A1 | Homo sapiens (human) | | 0.0013 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | | 0.0044 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | | 4 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | | 0.0118 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | | 0.0395 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | | 0.0141 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | | 0.0206 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | | 0.0135 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | | 0.048 |
| Protein kinase C epsilon type | Homo sapiens (human) | | 0.0767 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | | 0.2314 |
| Angiopoietin-1 receptor | Homo sapiens (human) | | 0.0823 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | | 0.1952 |
| Protein kinase C theta type | Homo sapiens (human) | | 0.1168 |
| Activin receptor type-1 | Homo sapiens (human) | | 1.1354 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | | 0.2195 |
| Focal adhesion kinase 1 | Homo sapiens (human) | | 0.078 |
| Protein kinase C zeta type | Homo sapiens (human) | | 0.1722 |
| Protein kinase C delta type | Homo sapiens (human) | | 0.1283 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | | 0.0288 |
| Aldehyde oxidase | Homo sapiens (human) | | 0.0023 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | | 0.0177 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | | 0.0587 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | | 0.0299 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | | 0.9655 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | | 0.0068 |
| Myotonin-protein kinase | Homo sapiens (human) | | 0.1735 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | | 0.0992 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | | 0.0331 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | | 0.0013 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | | 0.0004 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | | 0.0252 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | | 4.0032 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | | 0.0021 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | | 0.0034 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | | 0.438 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | | 0.0161 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | | 0.0038 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | | 0.0012 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | | 0.0018 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | | 0.0026 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | | 0.0024 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | | 0.0095 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | | 1.94 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | | 0.484 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | | 0.0027 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | | 0.057 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | | 0.0032 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | | 0.0003 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | | 0.0095 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | | 0.0006 |
| Lysine--tRNA ligase | Homo sapiens (human) | | 0.0049 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | | 0.0141 |
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | | 0.0005 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | | 0.1448 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | | 0.0037 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | | 0.183 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | | 0.0002 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | | 0.0477 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | | 0.0004 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | | 0.1995 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | | 0.0448 |
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Homo sapiens (human) | | 0.037 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | | 1 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | | 0.0598 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | | 0.068 |
| Coiled-coil domain-containing protein 6 | Homo sapiens (human) | | 0.0022 |
| NT-3 growth factor receptor | Homo sapiens (human) | | 0.0002 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | | 0.0025 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | | 0.0055 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | | 0.5052 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | | 0.1475 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | | 0.016 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | | 0.0004 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | | 2.775 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | | 0.0017 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | | 0.0008 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | | 0.0432 |
| Rho-associated protein kinase 2 | Bos taurus (cattle) | | 0.0417 |
| Myosin light chain kinase 3 | Homo sapiens (human) | | 0.1585 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | | 0.1464 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | | 0.0087 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.0077 |
| Mitogen-activated protein kinase kinase kinase 21 | Homo sapiens (human) | | 1.1175 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | | 0.0032 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | | 0.0067 |
| Testis-specific serine/threonine-protein kinase 1 | Mus musculus (house mouse) | | 0.0003 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | | 0.012 |
| Protein kinase C eta type | Rattus norvegicus (Norway rat) | | 0.274 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | | 0.0005 |
| Calcium/calmodulin-dependent protein kinase type 1B | Homo sapiens (human) | | 0.0044 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | | 0.0864 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | | 0.0105 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | | 0.0027 |
| Kinase suppressor of Ras 2 | Homo sapiens (human) | | 5.4 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | | 0.0552 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | | 0.0416 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | | 0.0001 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | | 0.0008 |
| Serine/threonine-protein kinase Nek8 | Homo sapiens (human) | | 0.0263 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | | 0.0035 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | | 0.232 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | | 0.0001 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | | 0.0537 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | | 2.639 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | | 0.0003 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | | 0.0001 |
| Kinase suppressor of Ras 1 | Homo sapiens (human) | | 6.265 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | | 1.1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | | 0.212 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | | 0.0028 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | | 0.1102 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | | 0.0032 |
| Misshapen-like kinase 1 | Homo sapiens (human) | | 0.0004 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | | 0.089 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | | 0.0359 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | | 1.84 |
| Cyclin-Y | Homo sapiens (human) | | 0.0518 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | | 0.226 |
| Myosin-IIIa | Homo sapiens (human) | | 0.0425 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | | 0.521 |
| Protein odd-skipped-related 1 | Homo sapiens (human) | | 0.0402 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | | 0.0081 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | | 0.101 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | | 0.0007 |
| Serine/threonine-protein kinase haspin | Homo sapiens (human) | | 0.0422 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | | 0.0053 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | | 0.0107 |
| Myosin-IIIb | Homo sapiens (human) | | 0.0058 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | | 0.18 |
| Phosphorylase b kinase regulatory subunit beta | Homo sapiens (human) | | 0.0005 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | | 0.073 |
| Aurora kinase B | Homo sapiens (human) | | 0.007 |
| Lymphokine-activated killer T-cell-originated protein kinase | Homo sapiens (human) | | 0.0691 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | | 0.0001 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | | 0.0047 |
| Testis-specific serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.0038 |
| Testis-specific serine/threonine-protein kinase 3 | Homo sapiens (human) | | 0.0051 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | | 0.0122 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | | 0.0107 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | | 0.0246 |
| SRSF protein kinase 1 | Homo sapiens (human) | | 0.0337 |
| Mitogen-activated protein kinase kinase kinase 14 | Homo sapiens (human) | | 2.3 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | | 0.215 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | | 0.0092 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | | 0.0531 |
| Testis-specific serine/threonine-protein kinase 6 | Homo sapiens (human) | | 0.1525 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | | 0.0374 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | | 0.0014 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | | 0.0018 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | | 0.3669 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | | 0.0147 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | | 0.0142 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | | 0.0017 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | | 0.3655 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | | 6.5 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | | 0.456 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | | 0.203 |
| Inactive tyrosine-protein kinase PEAK1 | Homo sapiens (human) | | 0.0025 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | | 0.0723 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.0221 |
| Serine/threonine-protein kinase Sgk2 | Homo sapiens (human) | | 0.0159 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | | 5.3367 |
| NADPH oxidase 4 | Homo sapiens (human) | | 0.0708 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | | 0.0327 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | | 0.0059 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | | 0.0062 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | | 0.0122 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | | 0.0375 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | | 0.053 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | | 0.546 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | | 0.0003 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | | 0.0813 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | | 0.0039 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | | 0.0124 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | | 0.0666 |
| Ribosomal protein S6 kinase beta-2 | Homo sapiens (human) | | 0.0015 |
| Protein DBF4 homolog A | Homo sapiens (human) | | 0.0549 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | | 0.0386 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | | 0.0158 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | | 0.0161 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | | 0.003 |
| Death-associated protein kinase 2 | Homo sapiens (human) | | 0.0064 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | | 0.0001 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | | 0.0103 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | | 0.0295 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | | 0.0076 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | | 0.0044 |
| SRSF protein kinase 3 | Homo sapiens (human) | | 1.77 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | | 0.0443 |
| Aurora kinase C | Homo sapiens (human) | | 0.0022 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | | 0.0024 |
| Protein kinase C theta type | Rattus norvegicus (Norway rat) | | 0.274 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | | 0.3701 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | | 0.0012 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | | 0.1541 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | | 0.0335 |
| Serine/threonine-protein kinase WNK2 | Homo sapiens (human) | | 1.455 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | | 0.0017 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | | 1.1354 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | | 0.0002 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | | 0.0027 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | | 0.0065 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | | 2.675 |
| Chain A, Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | | 0.0003 |
| Chain X, Tyrosine-protein kinase Lyn | Homo sapiens (human) | | 0.0013 |
| Authors | Studies |
|---|
| Bonn, S; Bossemeyer, D; Breitenlechner, CB; Engh, RA; Erlbruch, A; Gassel, M; Herrero, S; Lehmann, W | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Feng, J; Isaka, N; Ito, M; Kureishi, Y; Nakano, T; Okinaka, T | 1 |
| Amano, M; Fukata, Y; Kaibuchi, K; Shimokawa, H | 1 |
| Brkic-Koric, D; Pfitzer, G; Sonntag-Bensch, D | 1 |
| Bauer, J; Parekh, N | 1 |
| Shimoda, LA; Sylvester, JT; Weigand, L | 1 |
| Chen, S; Dul, E; Hu, E; Khandekar, SS; Kirkpatrick, RB; Lee, D; Scott, GF; Smith, GK; Wright, LL; Yi, T | 1 |
| Bisschops, R; Cassiman, D; Fevery, J; Laleman, W; Nevens, F; Roskams, T; Severi, T; Van Landeghem, L; Van Pelt, J; Vander Elst, I; Zeegers, M | 1 |
| Ehrhard, M; Fritzsching, B; Frommhold, D; Koch, L; Poeschl, J; Ruef, P | 1 |
| Al-Ghabkari, A; MacDonald, JA; Moffat, LD; Sutherland, C; Walsh, MP | 1 |
| Kim, BJ; Kim, JN | 1 |
| Kihara, T; Matsumoto, T; Nakahashi, Y; Tachibana, K | 1 |
| Article | Year |
|---|
Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity.The Journal of biological chemistry, 2006, Aug-25, Volume: 281, Issue:34
Topics: Animals; Benzamides; Cattle; Cyclic AMP-Dependent Protein Kinases; Erlotinib Hydrochloride; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Models, Molecular; Mutagenesis, Site-Directed; Piperazines; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Quinazolines; Recombinant Fusion Proteins; rho-Associated Kinases; Structure-Activity Relationship; Substrate Specificity | 2006 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Regulation of Ca2+-independent smooth muscle contraction by alternative staurosporine-sensitive kinase.European journal of pharmacology, 1999, Jul-09, Volume: 376, Issue:3
Topics: Amides; Animals; Enzyme Inhibitors; Male; Microcystins; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Peptides, Cyclic; Phosphorylation; Pyridines; Rabbits; Rho Factor; Staurosporine; Vasoconstrictor Agents | 1999 |
Purification and in vitro activity of Rho-associated kinase.Methods in enzymology, 2000, Volume: 325Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Baculoviridae; Catalytic Domain; Cattle; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Staurosporine | 2000 |
Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase.The Journal of physiology, 2001, Jun-15, Volume: 533, Issue:Pt 3
Topics: Actin Cytoskeleton; Adenosine Triphosphate; Amides; Animals; Calcium; Carbachol; Drug Synergism; Enzyme Inhibitors; Female; Gastrointestinal Motility; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Staurosporine; Sulfhydryl Compounds; Sulfur | 2001 |
Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.Kidney international, 2003, Volume: 63, Issue:6
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gallic Acid; Indoles; Nifedipine; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Signal Transduction; Staurosporine; Vasoconstrictor Agents | 2003 |
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction | 2006 |
Expression, purification, and characterization of an enzymatically active truncated human rho-kinase I (ROCK I) domain expressed in Sf-9 insect cells.Protein and peptide letters, 2006, Volume: 13, Issue:4
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Amino Acid Sequence; Animals; Humans; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Molecular Weight; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyridines; rho-Associated Kinases; Spodoptera; Staurosporine | 2006 |
Both Ca2+ -dependent and -independent pathways are involved in rat hepatic stellate cell contraction and intrahepatic hyperresponsiveness to methoxamine.American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2
Topics: Actomyosin; Amides; Animals; Calcimycin; Calcium; Cell Shape; Cells, Cultured; Diacetyl; Enzyme Inhibitors; Liver; Male; Marine Toxins; Methoxamine; Myocytes, Cardiac; Myocytes, Smooth Muscle; Myosin-Light-Chain Kinase; Oxazoles; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Sulfonamides; Vasoconstrictor Agents | 2007 |
Lipid A decreases human erythrocytes deformability by increasing intracellular Ca(2+): effects of verapamil, staurosporine and the rho-kinase inhibitor Y-27632.Clinical hemorheology and microcirculation, 2011, Volume: 49, Issue:1-4
Topics: Adult; Amides; Calcium Channel Blockers; Calcium Signaling; Depression, Chemical; Drug Interactions; Erythrocyte Deformability; Escherichia coli; Humans; In Vitro Techniques; Lipid A; Male; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Shear Strength; Staurosporine; Verapamil | 2011 |
Prostate-apoptosis response-4 phosphorylation in vascular smooth muscle.Archives of biochemistry and biophysics, 2013, Jul-01, Volume: 535, Issue:1
Topics: Amides; Animals; Apoptosis Regulatory Proteins; Arteries; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Death-Associated Protein Kinases; Immunoprecipitation; Indoles; Male; Maleimides; Microcystins; Muscle Contraction; Muscle, Smooth, Vascular; Octoxynol; Phosphorylation; Protein Binding; Protein Phosphatase 1; Pyridines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; rho-Associated Kinases; Staurosporine; Threonine; Time Factors | 2013 |
The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine.Molecules and cells, 2019, Jun-30, Volume: 42, Issue:6
Topics: Acetophenones; Amides; Animals; Benzopyrans; Boron Compounds; Calcium; Carbazoles; Gastrointestinal Motility; Ghrelin; Inositol 1,4,5-Trisphosphate Receptors; Interstitial Cells of Cajal; Intestine, Small; Macrocyclic Compounds; Membrane Potentials; Mice; Mice, Inbred ICR; Motilin; Oligopeptides; Oxazoles; Protein Kinase C; Pyridines; Receptors, Ghrelin; rho-Associated Kinases; Signal Transduction; Staurosporine; Thapsigargin | 2019 |
Mechanical stiffness softening and cell adhesion are coordinately regulated by ERM dephosphorylation in KG-1 cells.Human cell, 2021, Volume: 34, Issue:6
Topics: Actins; Amides; Cell Adhesion; Cell Line, Tumor; Cytochalasin D; Cytoskeletal Proteins; Elasticity; Fibronectins; Humans; Leukemia, Myeloid; Leukocytes; Membrane Proteins; Microfilament Proteins; Microvilli; Phorbol Esters; Phosphorylation; Pyridines; Staurosporine | 2021 |