y 27632 has been researched along with sb 772077-b in 2 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (sb 772077-b) | Trials (sb 772077-b) | Recent Studies (post-2010) (sb 772077-b) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 5 | 0 | 4 |
| Protein | Taxonomy | y 27632 (IC50) | sb 772077-b (IC50) |
|---|---|---|---|
| Rho-associated protein kinase 2 | Homo sapiens (human) | 0.0065 | |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | 0.014 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 7 | |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | 0.324 | |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | 1.95 | |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | 9.1 | |
| Rho-associated protein kinase 1 | Homo sapiens (human) | 0.0084 | |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | 0.035 | |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | 1.64 | |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | 1.29 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bamford, M; Behm, DJ; Bentley, R; Chen, Z; Doe, C; Dul, E; Grygielko, E; Hu, E; Jolivette, L; Jung, D; Khandekar, S; Kirkpatrick, R; Lafferty, R; Lee, D; Marino, JP; Panchal, T; Smith, GK; Stavenger, R; Webb, C; Willette, R; Wright, LL; Yi, T | 1 |
| Duggan, N; Hollingworth, G; Kosaka, T; Schuler, W; Shaw, D; Soldermann, N; Sprague, E; Thomas, M; van Eis, MJ; Vangrevelinghe, E; Waters, N | 1 |
2 other study(ies) available for y 27632 and sb 772077-b
| Article | Year |
|---|---|
Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Cells, Cultured; Cytokines; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Macrophages; Male; Oxadiazoles; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Vasodilator Agents | 2007 |
Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension.
Topics: Animals; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Hypertension, Pulmonary; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Rats; Rats, Inbred Lew; rho-Associated Kinases; Structure-Activity Relationship | 2014 |