y 27632 has been researched along with sb 202190 in 8 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (sb 202190) | Trials (sb 202190) | Recent Studies (post-2010) (sb 202190) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 651 | 0 | 202 |
| Protein | Taxonomy | y 27632 (IC50) | sb 202190 (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | 0.08 | |
| Bromodomain-containing protein 4 | Homo sapiens (human) | 2.95 | |
| Tyrosinase | Mus musculus (house mouse) | 0.03 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.08 | |
| Casein kinase I isoform delta | Homo sapiens (human) | 0.188 | |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | 0.08 | |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | 0.1038 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.0625 | |
| Tau-tubulin kinase 2 | Homo sapiens (human) | 9.34 | |
| large T antigen | Betapolyomavirus macacae | 4.87 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caivano, M; Cohen, P; Davies, SP; Reddy, H | 1 |
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Caldwell, RB; Caldwell, RW; Chandra, S; Iddings, JA; Romero, MJ; Shatanawi, A; Umapathy, NS; Verin, AD | 1 |
| Gahtan, V; Lawler, J; Maier, KG; Sadowitz, B; Seymour, KA; Stein, JJ | 1 |
| Akagi, M; Fukuda, K; Hamanishi, C; Nakagawa, K; Onodera, Y; Takehara, T; Teramura, T | 1 |
8 other study(ies) available for y 27632 and sb 202190
| Article | Year |
|---|---|
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides | 2000 |
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arginase; Boronic Acids; Cattle; Cell Line; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; Imidazoles; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Simvastatin | 2011 |
Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated.
Topics: Amides; Cell Movement; Cells, Cultured; Chemotaxis; Chromones; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organophosphonates; Protein Folding; Pyridines; Pyrimidines; Signal Transduction; Thrombospondin 1 | 2011 |
Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants.
Topics: Amides; Animals; Cartilage; Cattle; Cells, Cultured; Chondrocytes; Enzyme Inhibitors; Imidazoles; Matrix Metalloproteinase 13; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Stress, Mechanical | 2012 |