Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and pyrazolanthrone

y 27632 has been researched along with pyrazolanthrone in 5 studies

Compound Research Comparison

Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010)
(y 27632)		Studies
(pyrazolanthrone)		Trials
(pyrazolanthrone)		Recent Studies (post-2010) (pyrazolanthrone)
1,92438911,4842765

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)pyrazolanthrone (IC50)
Chain A, Mitogen-activated protein kinase 10Homo sapiens (human)0.15
Chain A, Mitogen-activated protein kinase 10Homo sapiens (human)0.15
Chain A, Mitogen-activated protein kinase 10Homo sapiens (human)0.15
TPA: protein transporter TIM10Saccharomyces cerevisiae S288C20.2
TPA: protein transporter TIM23Saccharomyces cerevisiae S288C6.31
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)0.72
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)8
Dual specificity protein kinase TTKHomo sapiens (human)0.8987
Mitogen-activated protein kinase 8Homo sapiens (human)0.921
Mitogen-activated protein kinase 9Homo sapiens (human)1.0111
Tyrosine-protein kinase JAK3Homo sapiens (human)0.957
Mitogen-activated protein kinase 10Homo sapiens (human)1.4193
Mitogen-activated protein kinase 14Homo sapiens (human)0.15

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Chen, JW; Chen, YH; Chen, YL; Hsieh, LY; Ku, HH; Lin, CY; Lin, FY; Lin, SJ; Wang, SH; Wang, YC1
Cao, H; Chen, Z; Chi, S; Guo, S; Hu, Q; Sun, T; Tao, H; Yang, J; Zhang, L; Zhu, H1

Other Studies

5 other study(ies) available for y 27632 and pyrazolanthrone

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity.
    Journal of cellular biochemistry, 2007, Jun-01, Volume: 101, Issue:3

    Topics: Amides; Anthracenes; Aorta; Blotting, Western; Boron Compounds; cdc42 GTP-Binding Protein; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Endothelial Cells; Enzyme Activation; Flavonoids; Humans; Imidazoles; Leucine; Mitogen-Activated Protein Kinases; Phosphorylation; Pravastatin; Protein Transport; Pyridines; rac1 GTP-Binding Protein; Thrombomodulin; Time Factors; Tumor Necrosis Factor-alpha

2007
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Amides; Anthracenes; Cell Differentiation; Cells, Cultured; Cellular Reprogramming; Cellular Reprogramming Techniques; Colforsin; Culture Media, Conditioned; Fibroblasts; Foreskin; Humans; Indoles; Male; Maleimides; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Pyrazoles; Pyridines; Pyrimidines; Transcription Factors

2020