Page last updated: 2024-09-03

y 27632 and potassium chloride

y 27632 has been researched along with potassium chloride in 46 studies

Compound Research Comparison

Studies (y 27632)	Trials (y 27632)	Recent Studies (post-2010) (y 27632)	Studies (potassium chloride)	Trials (potassium chloride)	Recent Studies (post-2010) (potassium chloride)
1,924	3	891	18,040	395	1,764

Protein Interaction Comparison

Protein	Taxonomy	y 27632 (IC50)	potassium chloride (IC50)
Sodium/potassium/calcium exchanger 4	Homo sapiens (human)		174000
Sodium/potassium/calcium exchanger 2	Homo sapiens (human)		280000

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	36 (78.26)	29.6817
2010's	9 (19.57)	24.3611
2020's	1 (2.17)	2.80

Authors

Authors	Studies
Fujikawa, H; Kaibuchi, K; Sato, M; Tani, E	1
Caivano, M; Cohen, P; Davies, SP; Reddy, H	1
Bertoglio, J; Le Mellionnec, E; Loirand, G; Pacaud, P; Sauzeau, V; Scalbert, E	1
Nobe, K; Paul, RJ	1
Jin, N; Li, L; Rhoades, RA; Swartz, DR; Wang, Z; Yancey, KW; Zhang, D	1
Webb, RC; Weber, DS	1
Burdyga, T; Kupittayanant, S; Wray, S	1
Beattie, DK; Davies, AH; Gosling, M; McGregor, E; Powell, JT; Ribbons, DM	1
Büyükafşar, K; Levent, A	2
Bing, W; Chacko, S; Chang, S; DiSanto, ME; Hypolite, JA; Rolf, L; Wein, AJ; Zderic, SA	1
Ghisdal, P; Morel, N; Vandenberg, G	1
Bauer, N; Casanova, N; Gebb, S; McMurtry, I; Morio, Y; Nagaoka, T; Oka, M	1
Ark, M; Büyükafşar, K; Levent, A	1
Burdyga, T; Ford, LE; Mitchell, RW; Ragozzino, J	1
Didion, SP; Faraci, FM; Mathur, S; Ryan, MJ; Sigmund, CD	1
Janssen, LJ; Keshavjee, S; Pertens, E; Tazzeo, T; Zuo, J	1
Arikan, O; Ark, M; Büyükafşar, K; Kubat, H; Ozveren, E	1
Arikan, O; Ark, M; Büyükafsar, K; Korkmaz, B; Kubat, H; Ozveren, E; Songu-Mize, E; Yazici, G	1
Borgsmiller, L; Call, C; Mohr, R; Ratz, PH; Speich, JE	1
Alvarez de Sotomayor, M; Herrera, MD; Marhuenda, E; Márquez-Martín, A; Pérez-Guerrero, C	1
Jiang, SZ; Li, ZL; Wang, DS; Wang, HJ; Yuan, M	1
Lonigro, AJ; Losapio, JL; Sprague, RS; Stephenson, AH	1
Hester, RL; Naik, JS; Xiang, L	1
Shimoda, LA; Sylvester, JT; Weigand, L	1
Da Silva, JS; Dotti, CG; Schubert, V	1
Baird, AW; Feighery, R; Quinn, T	1
Akça, T; Aydin, S; Büyükafşar, K; Nalan Tiftik, R; Sahan-Firat, S	1
Hetman, M; Kalita, K; Kharebava, G; Zheng, JJ	1
Barman, SA	1
Lai, EY; Nordquist, L; Patzak, A; Persson, AE; Sjöquist, M	1
Gebb, SA; Homma, N; Karoor, V; McMurtry, IF; Morio, Y; Nagaoka, T; Oka, M; Ota, H	1
Prieto, D; Simonsen, U; Stankevicius, E; Villalba, N	1
Ding, H; Huang, J; Isotani, E; Kamm, KE; Mizuno, Y; Stull, JT	1
Arai, K; Kamai, T; Mizuno, T; Nakanishi, K; Yamanishi, T	1
Duan, WG; Jiang, ZZ; Lin, Q; Shang, J; Shu, B; Yan, M; Yao, JC; Yu, ZP; Yun, Y; Zhang, LY	1
Joh, S; Kawaguchi, T; Kuji, A; Satoh, K	1
Cole, WC; Hollywood, M; McHale, N; Sergeant, G; Thornbury, K; Walsh, MP	1
Baeyens, N; Horman, S; Morel, N; Rider, M; Vertommen, D	1
Gui, Y; Jiang, J; Li, D; Li, H; Li, J; Tian, R; Walsh, MP; Wang, L; Wang, Y; Wang, Z; Yin, H; Zheng, XL	1
Balkanci, ZD; Bayrak, S; Erdem, A; Karabulut, I; Karaismailoğlu, S; Pehlivanoğlu, B	1
Ark, M; Aypar, E; Demirtaş, A; Gözübüyük, G; Ozdemir, A; Şahan, G; Turan, NN	1
Astarci, E; Aydinoglu, F; Balli, E; Ergurhan Kiroglu, O; Ogulener, N	1
Alp Yildirim, Fİ; Ark, M; Aypar, E; Kaleli Durman, D; Özdemir, O; Uydeş Doğan, BS	1
Huang, S; Qi, F; Wang, Z; Wu, Q; Yang, S	1
Huang, S; Jin, F; Liu, Y; Qi, F; Yang, S	1

Other Studies

46 other study(ies) available for y 27632 and potassium chloride

Article	Year
Involvement of Rho-kinase-mediated phosphorylation of myosin light chain in enhancement of cerebral vasospasm. Circulation research, 2000, Aug-04, Volume: 87, Issue:3 Topics: Amides; Animals; Basilar Artery; Calcium; Calmodulin; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phosphoprotein Phosphatases; Phosphorylation; Potassium Chloride; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Serotonin; Subarachnoid Hemorrhage; Vasoconstrictor Agents; Vasodilator Agents; Vasospasm, Intracranial	2000
Specificity and mechanism of action of some commonly used protein kinase inhibitors. The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides	2000
Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. Circulation research, 2001, Jun-08, Volume: 88, Issue:11 Topics: ADP Ribose Transferases; Amides; Animals; Aorta, Thoracic; Botulinum Toxins; Cell Division; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Urotensins; Vasoconstriction; Vasoconstrictor Agents	2001
Distinct pathways of Ca(2+) sensitization in porcine coronary artery: effects of Rho-related kinase and protein kinase C inhibition on force and intracellular Ca(2+). Circulation research, 2001, Jun-22, Volume: 88, Issue:12 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Enzyme Activators; Enzyme Inhibitors; In Vitro Techniques; Intracellular Fluid; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Sarcoplasmic Reticulum; Signal Transduction; Stress, Mechanical; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasoconstrictor Agents	2001
Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle. Journal of muscle research and cell motility, 2001, Volume: 22, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Antineoplastic Agents; Aorta; Azepines; Calcium; Colchicine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Male; Microtubules; Muscle Contraction; Muscle, Smooth, Vascular; Nocodazole; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents	2001
Enhanced relaxation to the rho-kinase inhibitor Y-27632 in mesenteric arteries from mineralocorticoid hypertensive rats. Pharmacology, 2001, Volume: 63, Issue:3 Topics: Amides; Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Mesenteric Arteries; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Serotonin; Vasodilation	2001
The effects of inhibiting Rho-associated kinase with Y-27632 on force and intracellular calcium in human myometrium. Pflugers Archiv : European journal of physiology, 2001, Volume: 443, Issue:1 Topics: Amides; Calcium; Enzyme Inhibitors; Female; Humans; Intracellular Signaling Peptides and Proteins; Myometrium; Oxytocin; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Uterine Contraction	2001
Circumferential stretching of saphenous vein smooth muscle enhances vasoconstrictor responses by Rho kinase-dependent pathways. Cardiovascular research, 2002, Volume: 53, Issue:1 Topics: Adenosine; Amides; Cromakalim; Cycloheximide; Enzyme Inhibitors; Gadolinium; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Pulsatile Flow; Pyridines; rho-Associated Kinases; Saphenous Vein; Serotonin; Signal Transduction; Stents; Vasoconstrictor Agents; Vasodilator Agents	2002
Involvement of Rho/Rho-kinase signalling in the contractile activity and acetylcholine release in the mouse gastric fundus. Biochemical and biophysical research communications, 2003, Apr-11, Volume: 303, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Amides; Animals; Carbachol; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Fundus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction	2003
Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase. American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:5 Topics: Amides; Animals; Enzyme Inhibitors; Hypertrophy; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoenzymes; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocytes, Smooth Muscle; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; RNA, Messenger; Urinary Bladder; Urinary Bladder Neck Obstruction	2003
Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries. The Journal of physiology, 2003, Sep-15, Volume: 551, Issue:Pt 3 Topics: Aluminum Compounds; Amides; Animals; Aorta; Barium; Calcium; Calcium Channel Blockers; Calcium Signaling; Enzyme Inhibitors; Fluorides; GTP-Binding Proteins; Inositol Phosphates; Intracellular Signaling Peptides and Proteins; Male; Mesenteric Arteries; Mitochondria; Muscle Contraction; Muscle, Smooth, Vascular; Nimodipine; Norepinephrine; Potassium Channel Blockers; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Vasoconstrictor Agents	2003
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats. American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:4 Topics: Amides; Animals; Blood Pressure; Chromones; Enzyme Inhibitors; Hypertension, Pulmonary; Hypoxia; Indoles; Injections, Intravenous; Intracellular Signaling Peptides and Proteins; Male; Maleimides; Morpholines; Nifedipine; Potassium Chloride; Protein Serine-Threonine Kinases; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Vasodilator Agents	2004
Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens. British journal of pharmacology, 2003, Volume: 140, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Animals; Blotting, Western; Electric Stimulation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Guanethidine; Intracellular Signaling Peptides and Proteins; Male; Mice; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Vas Deferens	2003
Force and myosin light chain phosphorylation in dog airway smooth muscle activated in different ways. Respiratory physiology & neurobiology, 2003, Sep-16, Volume: 137, Issue:2-3 Topics: Acetylcholine; Amides; Androstadienes; Animals; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Isometric Contraction; Marine Toxins; Muscle, Smooth; Myosin Light Chains; Oxazoles; Phosphorylation; Potassium Chloride; Pyridines; Tetany; Trachea; Wortmannin	2003
Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Amides; Angiotensin II; Animals; Aorta; Carotid Arteries; Infusion Pumps, Implantable; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitroprusside; Papaverine; Phenylephrine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Sequence Deletion; Serotonin; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	2004
KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase. American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:4 Topics: Amides; Bronchi; Calcium; Enzyme Inhibitors; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle, Smooth; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Respiratory Mucosa; rho-Associated Kinases; rhoA GTP-Binding Protein	2004
Expression of Rho-kinase (ROCK-1 and ROCK-2) and its substantial role in the contractile activity of the sheep ureter. British journal of pharmacology, 2004, Volume: 143, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Aorta; Atropine; Blotting, Western; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Guanethidine; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Sheep; Tetrodotoxin; Ureter; Vasoconstrictor Agents; Vasodilator Agents	2004
Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats. European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3 Topics: Acetylcholine; Amides; Angiotensin II; Animals; Blotting, Western; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mesenteric Arteries; Nitrates; Nitrites; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; Sodium Chloride; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents	2004
Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery. Cell biochemistry and biophysics, 2004, Volume: 41, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Biophysics; Calcium; Dose-Response Relationship, Drug; Humans; Models, Biological; Nifedipine; Potassium Chloride; Protein Isoforms; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Serotonin; Umbilical Arteries	2004
ROK-induced cross-link formation stiffens passive muscle: reversible strain-induced stress softening in rabbit detrusor. American journal of physiology. Cell physiology, 2005, Volume: 289, Issue:1 Topics: Amides; Animals; Calcium; Carbachol; Elasticity; Enzyme Activation; Enzyme Inhibitors; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscarinic Agonists; Muscle, Smooth; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Solutions; Stress, Mechanical; Urinary Bladder; Viscosity	2005
Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin. Pharmacology, 2005, Volume: 74, Issue:4 Topics: Amides; Animals; Aorta, Thoracic; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; In Vitro Techniques; Indoles; Male; Mevalonic Acid; Muscle Relaxants, Central; Norepinephrine; Phenylephrine; Potassium Chloride; Pyridines; Rats; Rats, Inbred SHR; Simvastatin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2005
[Role of ROK in contraction of rat femoral arteries after 14 d tail suspension]. Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering, 2004, Volume: 17, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Body Weight; Femoral Artery; Hindlimb Suspension; Intracellular Signaling Peptides and Proteins; Male; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents; Weightlessness Simulation	2004
5,6-EET-induced contraction of intralobar pulmonary arteries depends on the activation of Rho-kinase. Journal of applied physiology (Bethesda, Md. : 1985), 2005, Volume: 99, Issue:4 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Amides; Animals; Calcium Chloride; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Myosin Light Chains; Phosphorylation; Potassium Chloride; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rabbits; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents	2005
Enhanced role for RhoA-associated kinase in adrenergic-mediated vasoconstriction in gracilis arteries from obese Zucker rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic Agents; Aging; Amides; Animals; Arteries; Calcium Signaling; Gene Expression Regulation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Zucker; rho-Associated Kinases; rhoA GTP-Binding Protein; Thinness; Vasoconstriction	2006
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats. American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction	2006
Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor-dependent manner. The Journal of cell biology, 2006, Jan-30, Volume: 172, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Amides; Animals; Carrier Proteins; Cells, Cultured; Dendritic Spines; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Biological; Neurons; Potassium Chloride; Profilins; Protein Serine-Threonine Kinases; Pyridines; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; rho-Associated Kinases; rhoA GTP-Binding Protein; Subcellular Fractions; Synaptosomes	2006
Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction. European journal of pharmacology, 2006, Mar-18, Volume: 534, Issue:1-3 Topics: Amides; Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Cholecystokinin; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gallbladder; Guinea Pigs; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Thapsigargin	2006
Contribution of Rho-kinase in human gallbladder contractions. European journal of pharmacology, 2006, Jul-01, Volume: 540, Issue:1-3 Topics: Aged; Amides; Blotting, Western; Carbachol; Cholecystokinin; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Female; Gallbladder; Histamine; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle Contraction; Neurokinin A; Peptide Fragments; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Serotonin	2006
Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-27, Volume: 26, Issue:39 Topics: 4-Aminopyridine; Amides; Animals; Animals, Newborn; Bicuculline; Brain-Derived Neurotrophic Factor; Butadienes; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Chromones; COS Cells; Cysteine-Rich Protein 61; Gene Expression Regulation; Genes, fos; Hippocampus; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; N-Methylaspartate; Neurons; Nitriles; Potassium Chloride; Prosencephalon; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; RNA Interference; Serum Response Factor; Signal Transduction; Synaptic Transmission; Transcription Factors; Transcription, Genetic; Transfection	2006
Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:2 Topics: Amides; Animals; Blotting, Western; Carbazoles; Endothelin-1; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Intracellular Signaling Peptides and Proteins; Male; Maleimides; Muscle, Smooth, Vascular; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Species Specificity; Vasoconstriction	2007
Proinsulin C-peptide constricts glomerular afferent arterioles in diabetic mice. A potential renoprotective mechanism. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:3 Topics: Amides; Angiotensin II; Animals; Arterioles; C-Peptide; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Kidney Glomerulus; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Norepinephrine; Potassium Chloride; Pyridines; Rho Factor; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents	2008
Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation. Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:6 Topics: Amides; Animals; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Activation; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Peptides, Cyclic; Perfusion; Potassium Chloride; Pulmonary Artery; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Serotonin; Signal Transduction; Vasoconstriction	2007
Rho kinase is involved in Ca2+ entry of rat penile small arteries. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Amides; Animals; Arteries; Bacterial Toxins; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Penis; Phenylephrine; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; rho-Associated Kinases; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents	2008
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo. American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:2 Topics: Amides; Animals; Calcium; Calcium Signaling; Calmodulin; Carbachol; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Mice; Mice, Transgenic; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Myosin Light Chains; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Naphthalenes; Phosphoproteins; Phosphorylation; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Urinary Bladder	2008
Expression of RhoA mRNA and activated RhoA in urothelium and smooth muscle, and effects of a Rho-kinase inhibitor on contraction of the porcine urinary bladder. Neurourology and urodynamics, 2009, Volume: 28, Issue:6 Topics: Amides; Animals; Blotting, Western; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Female; Immunohistochemistry; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Swine; Urinary Bladder; Urothelium	2009
Rho kinase inhibitor Y-27632 down-regulates norepinephrine synthesis and release in PC12 cells. Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:6 Topics: Acetylcholine; Amides; Animals; Blotting, Western; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Nerve Growth Factor; Neurites; Norepinephrine; PC12 Cells; Potassium Chloride; Pyridines; Rats; rho-Associated Kinases	2009
Features of distinct contractions induced with a high and a low concentration of KCl, noradrenaline, and histamine in swine lingual artery. Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 381, Issue:2 Topics: Amides; Animals; Arteries; Boron Compounds; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; Histamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Norepinephrine; Potassium Chloride; Pyridines; rho-Associated Kinases; Signal Transduction; Swine; Tongue; Vasoconstrictor Agents	2010
Rho-associated kinase plays a role in rabbit urethral smooth muscle contraction, but not via enhanced myosin light chain phosphorylation. American journal of physiology. Renal physiology, 2011, Volume: 300, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Electric Stimulation; Male; Muscle Contraction; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phenylephrine; Phosphorylation; Potassium Chloride; Pyridines; Rabbits; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Urethra	2011
Identification and functional implication of a Rho kinase-dependent moesin-EBP50 interaction in noradrenaline-stimulated artery. American journal of physiology. Cell physiology, 2010, Volume: 299, Issue:6 Topics: Amides; Animals; Antihypertensive Agents; Aorta; Carrier Proteins; Ionomycin; Male; Mesenteric Arteries; Microfilament Proteins; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phosphoproteins; Potassium Chloride; Protein Binding; Protein Kinase C; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; RNA, Small Interfering; Sodium-Hydrogen Exchangers	2010
Atorvastatin inhibits myocardin expression in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:1 Topics: Actins; Amides; Animals; Aorta; Atorvastatin; Blotting, Western; Cell Line; Enzyme Inhibitors; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Mevalonic Acid; Mice; Mice, Inbred C57BL; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Polyisoprenyl Phosphates; Potassium Chloride; Pyridines; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Trans-Activators; Vasoconstriction	2012
The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:11 Topics: Amides; Animals; Calcium Channels, L-Type; Carbachol; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Hypercholesterolemia; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Urinary Bladder	2012
Chronic ouabain treatment induces Rho kinase activation. Archives of pharmacal research, 2015, Volume: 38, Issue:10 Topics: Amides; Animals; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Male; Myosin-Light-Chain Phosphatase; Ouabain; Phenylephrine; Potassium Chloride; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases	2015
Effects of ethanol on RhoA/Rho-kinase-mediated calcium sensitization in mouse lung parenchymal tissue. European journal of pharmacology, 2015, Oct-05, Volume: 764 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Calcium; Ethanol; Lung; Male; Mice; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction	2015
Atorvastatin acutely reduces the reactivity to spasmogens in rat aorta: implication of the inhibition of geranylgeranylation and MYPT-1 phosphorylation. Fundamental & clinical pharmacology, 2016, Volume: 30, Issue:2 Topics: Amides; Animals; Aorta, Thoracic; Atorvastatin; Endothelin-1; Endothelium; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Norepinephrine; Phosphorylation; Polyisoprenyl Phosphates; Potassium Chloride; Prenylation; Protein Phosphatase 1; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Sesquiterpenes	2016
Sevoflurane and isoflurane inhibit KCl-induced Class II phosphoinositide 3-kinase α subunit mediated vasoconstriction in rat aorta. BMC anesthesiology, 2016, 08-18, Volume: 16, Issue:1 Topics: Amides; Anesthetics, Inhalation; Animals; Aorta; Blotting, Western; Chromones; Class II Phosphatidylinositol 3-Kinases; Dose-Response Relationship, Drug; Isoflurane; Male; Methyl Ethers; Morpholines; Myosin Light Chains; Phosphorylation; Potassium Chloride; Protein Phosphatase 1; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Sevoflurane; Vasoconstriction; Vasodilation	2016
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas. BMC anesthesiology, 2021, 09-01, Volume: 21, Issue:1 Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Isoflurane; Morpholines; Phosphatidylinositol 3-Kinases; Potassium Chloride; Pyridines; Rats, Inbred OLETF; Rats, Wistar; rho-Associated Kinases; Sevoflurane; Vasoconstriction	2021