Page last updated: 2024-09-03

y 27632 and podophyllotoxin

y 27632 has been researched along with podophyllotoxin in 4 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(podophyllotoxin)
Trials
(podophyllotoxin)
Recent Studies (post-2010) (podophyllotoxin)
1,92438913,119226782

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)podophyllotoxin (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)2.145
Tubulin alpha-1A chainSus scrofa (pig)0.6733
Tubulin beta chainSus scrofa (pig)0.622
Glucocorticoid receptorHomo sapiens (human)0.014
Tubulin beta-4A chainHomo sapiens (human)1.7233
Tubulin beta chainHomo sapiens (human)1.7233
Cytochrome P450 3A4Homo sapiens (human)0.6
Tubulin alpha-3C chainHomo sapiens (human)1.7233
Cytochrome P450 2C9 Homo sapiens (human)4
Cytochrome P450 2C19Homo sapiens (human)5
Tubulin alpha-1B chainHomo sapiens (human)1.7233
Tubulin alpha-4A chainHomo sapiens (human)1.7233
Tubulin beta-4B chainHomo sapiens (human)1.7233
Tubulin beta-3 chainHomo sapiens (human)1.7233
Tubulin beta-2A chainHomo sapiens (human)1.7233
Tubulin beta-8 chainHomo sapiens (human)1.7233
Calcium-activated potassium channel subunit alpha-1Rattus norvegicus (Norway rat)0.56
Tubulin beta-2B chainBos taurus (cattle)0.8685
Tubulin alpha-3E chainHomo sapiens (human)1.7233
Tubulin alpha-1A chainHomo sapiens (human)1.7233
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)0.907
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)0.7744
Tubulin alpha-1C chainHomo sapiens (human)1.7233
Tubulin beta-6 chainHomo sapiens (human)1.7233
Tubulin beta-2B chainHomo sapiens (human)1.7233
Tubulin beta-1 chainHomo sapiens (human)1.7233

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Chakraborty, C; Nicola, C; Shields, SK1
Chen, M; Duan, H; Jiang, Z; Miao, J; Sun, L; Wang, Y; Wu, M; Zhang, L; Zhang, S; Zhang, X; Zhu, X1
Defant, A; Mancini, I1

Other Studies

4 other study(ies) available for y 27632 and podophyllotoxin

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Rho guanosine 5'-triphosphatases differentially regulate insulin-like growth factor I (IGF-I) receptor-dependent and -independent actions of IGF-II on human trophoblast migration.
    Endocrinology, 2007, Volume: 148, Issue:10

    Topics: ADP Ribose Transferases; Amides; Botulinum Toxins; cdc42 GTP-Binding Protein; Cell Line; Cell Movement; Enzyme Inhibitors; Gene Silencing; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Intracellular Signaling Peptides and Proteins; Peptide Fragments; Podophyllotoxin; Protein Serine-Threonine Kinases; Pyridines; rac1 GTP-Binding Protein; Receptor, IGF Type 1; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein; Trophoblasts

2007
Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:8

    Topics: Amides; Angiogenesis Inhibitors; Animals; Blood Vessels; Cell Cycle; Cell Movement; Cell Proliferation; Chickens; Chorioallantoic Membrane; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Mice, Nude; Microtubules; Neovascularization, Pathologic; Neovascularization, Physiologic; Paclitaxel; Podophyllotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays

2013
Design, Synthesis and Cancer Cell Growth Inhibition Evaluation of New Aminoquinone Hybrid Molecules.
    Molecules (Basel, Switzerland), 2019, Jun-14, Volume: 24, Issue:12

    Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Neoplasms; Podophyllotoxin; Pyridines; Quinolines; rho-Associated Kinases; Stilbenes; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators

2019