Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and pi103

y 27632 has been researched along with pi103 in 4 studies

Compound Research Comparison

Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010)
(y 27632)		Studies
(pi103)		Trials
(pi103)		Recent Studies (post-2010) (pi103)
1,92438911810139

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)pi103 (IC50)
Chain A, PHOSPHOTIDYLINOSITOL 3 KINASE 59FDrosophila melanogaster (fruit fly)2.3
Chain A, PHOSPHOTIDYLINOSITOL 3 KINASE 59FDrosophila melanogaster (fruit fly)2.3
Chain A, PHOSPHOTIDYLINOSITOL 3 KINASE 59FDrosophila melanogaster (fruit fly)2.3
Chain A, PHOSPHOTIDYLINOSITOL 3 KINASE 59FDrosophila melanogaster (fruit fly)2.3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0155
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alphaHomo sapiens (human)1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)0.0585
Cytochrome P450 1A2Homo sapiens (human)0.012
Cytochrome P450 3A4Homo sapiens (human)0.0111
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.011
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.011
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.011
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.0114
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.2038
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0346
Serine/threonine-protein kinase mTORHomo sapiens (human)0.4746
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.069
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)0.0215
Rapamycin-insensitive companion of mTORHomo sapiens (human)0.083
Regulatory-associated protein of mTORHomo sapiens (human)0.02
Target of rapamycin complex 2 subunit MAPKAP1Homo sapiens (human)0.083
Target of rapamycin complex subunit LST8Homo sapiens (human)0.041

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

4 other study(ies) available for y 27632 and pi103

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013