Page last updated: 2024-09-03

y 27632 and pf 573228

y 27632 has been researched along with pf 573228 in 3 studies

Compound Research Comparison

Studies (y 27632)	Trials (y 27632)	Recent Studies (post-2010) (y 27632)	Studies (pf 573228)	Trials (pf 573228)	Recent Studies (post-2010) (pf 573228)
1,924	3	891	80	0	72

Protein Interaction Comparison

Protein	Taxonomy	pf 573228 (IC50)
Cyclin-dependent kinase 1	Homo sapiens (human)	0.743
G2/mitotic-specific cyclin-B1	Homo sapiens (human)	0.743
Glycogen synthase kinase-3 beta	Homo sapiens (human)	1
Cyclin-dependent kinase 7	Homo sapiens (human)	0.5985
Cyclin-H	Homo sapiens (human)	1
CDK-activating kinase assembly factor MAT1	Homo sapiens (human)	1
Focal adhesion kinase 1	Homo sapiens (human)	0.0563
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	1

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Duan, Y; Han, J; Liao, C; Xie, Z; Yang, X	1
Ju, Y; Song, G; Xu, B	1

Reviews

1 review(s) available for y 27632 and pf 573228

Article	Year
Small-Molecule Kinase Inhibitors for the Treatment of Nononcologic Diseases. Journal of medicinal chemistry, 2021, 02-11, Volume: 64, Issue:3 Topics: Animals; Autoimmune Diseases; Drug Discovery; Humans; Models, Molecular; Protein Kinase Inhibitors; Small Molecule Libraries	2021

Other Studies

2 other study(ies) available for y 27632 and pf 573228

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Role of p38, ERK1/2, focal adhesion kinase, RhoA/ROCK and cytoskeleton in the adipogenesis of human mesenchymal stem cells. Journal of bioscience and bioengineering, 2014, Volume: 117, Issue:5 Topics: Adipocytes; Adipogenesis; Amides; Butadienes; Cells, Cultured; Cytochalasin D; Cytoskeleton; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Humans; Imidazoles; Mesenchymal Stem Cells; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinolones; rho-Associated Kinases; rhoA GTP-Binding Protein; Sulfones	2014

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Role of p38, ERK1/2, focal adhesion kinase, RhoA/ROCK and cytoskeleton in the adipogenesis of human mesenchymal stem cells.

Journal of bioscience and bioengineering, 2014, Volume: 117, Issue:5

Topics: Adipocytes; Adipogenesis; Amides; Butadienes; Cells, Cultured; Cytochalasin D; Cytoskeleton; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Humans; Imidazoles; Mesenchymal Stem Cells; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinolones; rho-Associated Kinases; rhoA GTP-Binding Protein; Sulfones

2014