Page last updated: 2024-09-03

y 27632 and perifosine

y 27632 has been researched along with perifosine in 2 studies

Compound Research Comparison

Studies (y 27632)	Trials (y 27632)	Recent Studies (post-2010) (y 27632)	Studies (perifosine)	Trials (perifosine)	Recent Studies (post-2010) (perifosine)
1,924	3	891	245	31	140

Protein Interaction Comparison

Protein	Taxonomy	perifosine (IC50)
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	1.2
Ubiquitin carboxyl-terminal hydrolase isozyme L3	Homo sapiens (human)	0.05
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	5.3
Mitogen-activated protein kinase 14	Homo sapiens (human)	1.2

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Ishimaru, Y; Narahara, S; Sakamoto, A; Sugiuchi, H; Yamaguchi, R; Yamaguchi, Y; Yamamoto, T	1

Other Studies

2 other study(ies) available for y 27632 and perifosine

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Substance P enhances tissue factor release from granulocyte-macrophage colony-stimulating factor-dependent macrophages via the p22phox/β-arrestin 2/Rho A signaling pathway. Blood cells, molecules & diseases, 2016, Volume: 57 Topics: Acetophenones; Adipocytes; Amides; Aprepitant; Arrestins; Benzopyrans; beta-Arrestin 2; beta-Arrestins; Dynamins; Free Radical Scavengers; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Activation; Macrophages; Morpholines; NADPH Oxidases; Neurokinin-1 Receptor Antagonists; Phosphorylcholine; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Substance P; Thiocarbamates; Thromboplastin	2016

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Substance P enhances tissue factor release from granulocyte-macrophage colony-stimulating factor-dependent macrophages via the p22phox/β-arrestin 2/Rho A signaling pathway.

Blood cells, molecules & diseases, 2016, Volume: 57

Topics: Acetophenones; Adipocytes; Amides; Aprepitant; Arrestins; Benzopyrans; beta-Arrestin 2; beta-Arrestins; Dynamins; Free Radical Scavengers; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Activation; Macrophages; Morpholines; NADPH Oxidases; Neurokinin-1 Receptor Antagonists; Phosphorylcholine; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Substance P; Thiocarbamates; Thromboplastin

2016