y 27632 has been researched along with pd 173074 in 3 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (pd 173074) | Trials (pd 173074) | Recent Studies (post-2010) (pd 173074) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 160 | 0 | 106 |
| Protein | Taxonomy | y 27632 (IC50) | pd 173074 (IC50) |
|---|---|---|---|
| Platelet-derived growth factor receptor beta | Mus musculus (house mouse) | 0.028 | |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | 0.0217 | |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | 0.028 | |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | 0.19 | |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | 0.013 | |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | 0.5337 | |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | 0.0268 | |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | 0.19 | |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | 0.1325 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Brinkmann, H; Broughton, N; Claus, P; Grothe, C; Hensel, N; Rademacher, S; Stockbrügger, I | 1 |
3 other study(ies) available for y 27632 and pd 173074
| Article | Year |
|---|---|
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Bilateral crosstalk of rho- and extracellular-signal-regulated-kinase (ERK) pathways is confined to an unidirectional mode in spinal muscular atrophy (SMA).
Topics: Actin Cytoskeleton; Amides; Animals; Cell Line; Cell Proliferation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Mice; Muscular Atrophy, Spinal; Neurites; PC12 Cells; Pyrazoles; Pyridazines; Pyridines; Pyrimidines; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; SMN Complex Proteins | 2014 |