Page last updated: 2024-09-03

y 27632 and pd 0325901

y 27632 has been researched along with pd 0325901 in 5 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(pd 0325901)
Trials
(pd 0325901)
Recent Studies (post-2010) (pd 0325901)
1,92438912997256

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)pd 0325901 (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.015
Cytochrome P450 2D6Homo sapiens (human)0.015
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.006
Mitogen-activated protein kinase 1Homo sapiens (human)0.025
Dual specificity mitogen-activated protein kinase kinase 1Mus musculus (house mouse)0.0003
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)0.078
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)0.0285

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Cao, N; Cui, C; Liao, J; Liu, L; Liu, Z; Wang, J; Xiao, L; Xu, P; Yang, HT; Yu, L; Zhu, W1
Hashimoto, Y; Nakada, A; Nakamura, T; Shigeno, K; Shimada, H1
Anand, M; Bontovics, B; Chrenek, P; Fábián, R; Gócza, E; Lázár, B; Makarevich, AV; Maraghechi, P; Németh, K; Vašíček, J1

Other Studies

5 other study(ies) available for y 27632 and pd 0325901

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes.
    Cell research, 2011, Volume: 21, Issue:9

    Topics: Action Potentials; Amides; Animals; Benzamides; Calcium; Cell Differentiation; Culture Media, Serum-Free; Diphenylamine; Embryonic Stem Cells; Glycogen Synthase Kinase 3; MAP Kinase Kinase Kinases; Myocytes, Cardiac; Phenotype; Pyridines; Pyrimidines; Rats; rho-Associated Kinases

2011
Accelerated generation of human induced pluripotent stem cells with retroviral transduction and chemical inhibitors under physiological hypoxia.
    Biochemical and biophysical research communications, 2012, Jan-13, Volume: 417, Issue:2

    Topics: Amides; Animals; Benzamides; Butyrates; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Cell Line; Diphenylamine; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, myc; Humans; Induced Pluripotent Stem Cells; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, SCID; Octamer Transcription Factor-3; Pyrazoles; Pyridines; Pyrimidines; Retroviridae; SOXB1 Transcription Factors; Thiocarbamates; Thiosemicarbazones; Transduction, Genetic; Transgenes

2012
The effect of dual inhibition of Ras-MEK-ERK and GSK3β pathways on development of
    Zygote (Cambridge, England), 2020, Volume: 28, Issue:3

    Topics: Amides; Animals; Benzamides; Diphenylamine; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Enzyme Inhibitors; Female; Germ Layers; Glycogen Synthase Kinase 3 beta; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Pyrazoles; Pyridines; Pyrimidines; Rabbits; ras Proteins; Thiosemicarbazones

2020