y 27632 has been researched along with paxilline in 18 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (paxilline) | Trials (paxilline) | Recent Studies (post-2010) (paxilline) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 2,097 | 3 | 790 |
| Protein | Taxonomy | y 27632 (IC50) | paxilline (IC50) |
|---|---|---|---|
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | 33.55 | |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | 5 | |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | 5 | |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | 5 | |
| BZLF2 | Human herpesvirus 4 type 2 (Epstein-Barr virus type 2) | 2.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carbajal, JM; Gratrix, ML; Schaeffer, RC; Yu, CH | 1 |
| Akedo, H; Ayaki, M; Imamura, F; Mukai, M | 1 |
| Leopoldt, D; Lunn, JA; Rozengurt, E; Sinnett-Smith, J | 1 |
| Houle, F; Huot, J; Le Boeuf, F | 1 |
| Bolton, SJ; Huynh, TT; Norman, JC; Thomas, RA; Wardlaw, AJ; Williams, B | 1 |
| Annabi, B; Duhamel, S; Galipeau, J; Lejeune, L; Meriane, M | 1 |
| Ho, PY; Ho, YS; Lee, WS; Zhong, WB | 1 |
| Kano, Y; Katoh, K; Ookawara, S | 1 |
| Alpern, RJ; Huang, HC; Preisig, PA; Yang, X; Yin, H | 1 |
| Giehl, K; Goppelt-Struebe, M; Graness, A | 1 |
| Ammoun, S; Biebl, A; Flaiz, C; Hanemann, CO | 1 |
| Abe, T; Hara, Y; Tanaka, M | 1 |
| Pasapera, AM; Rericha, E; Schlaepfer, DD; Schneider, IC; Waterman, CM | 1 |
| Elad, N; Fässler, R; Geiger, B; Grashoff, C; Hirschfeld-Warneken, V; Medalia, O; Patla, I; Spatz, JP; Volberg, T | 1 |
| Cheng, L; Cheng, R; Hu, T; Shao, MY; Wang, FM; Yang, H; Zhou, XD | 1 |
| Combrink, K; Patil, RV; Ramachandran, C; Sharif, NA; Srinivas, SP | 1 |
| Chaponnier, C; Gunning, PW; Kavallaris, M; O'Neill, GM; Pasquier, E; Po'uha, ST; Shum, MS | 1 |
| Chen, Y; Chou, WC; Ding, YM; Wu, YC | 1 |
18 other study(ies) available for y 27632 and paxilline
| Article | Year |
|---|---|
ROCK mediates thrombin's endothelial barrier dysfunction.
Topics: Actins; Amides; Animals; Capillary Permeability; Cattle; Cytoskeletal Proteins; Cytoskeleton; Endothelium, Vascular; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; Myosin Light Chains; Myosins; Paxillin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; rho-Associated Kinases; Thrombin; Tissue Adhesions; Tyrosine | 2000 |
Y-27632, an inhibitor of rho-associated protein kinase, suppresses tumor cell invasion via regulation of focal adhesion and focal adhesion kinase.
Topics: Actins; Amides; Animals; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Cytoskeletal Proteins; Drug Interactions; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Lysophospholipids; Neoplasm Invasiveness; Paxillin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Rats; rho-Associated Kinases; Tumor Cells, Cultured; Tyrosine | 2000 |
Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Amides; Animals; Bombesin; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Mice; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Pyridines; Retinoblastoma-Like Protein p130; rho-Associated Kinases; Stress Fibers | 2001 |
Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities.
Topics: Amides; Benzoquinones; CD18 Antigens; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; DNA, Complementary; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Gene Transfer Techniques; Genes, Dominant; Green Fluorescent Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Luminescent Proteins; Mutation; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Pyridines; Quinones; rhoA GTP-Binding Protein; src-Family Kinases; Time Factors; Tyrosine; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2; Vinculin | 2004 |
Mechanical stretch has contrasting effects on mediator release from bronchial epithelial cells, with a rho-kinase-dependent component to the mechanotransduction pathway.
Topics: Amides; Bronchi; Cell Line; Chemokine CCL5; Elasticity; Enzyme Inhibitors; Epithelial Cells; Humans; Interleukin-8; Intracellular Signaling Peptides and Proteins; Mechanotransduction, Cellular; Models, Biological; Paxillin; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Stress, Mechanical | 2006 |
Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphate-induced mobilization of marrow-derived str
Topics: Actin Cytoskeleton; Amides; Animals; Bone Marrow Cells; Cell Shape; Cells, Cultured; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Flavonoids; Focal Adhesion Protein-Tyrosine Kinases; Hydroxamic Acids; Indoles; Intracellular Signaling Peptides and Proteins; Lysophospholipids; MAP Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Paxillin; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Sphingosine; Stromal Cells | 2006 |
Terbinafine inhibits endothelial cell migration through suppression of the Rho-mediated pathway.
Topics: Amides; Angiogenesis Inhibitors; Cell Adhesion; Cell Movement; Endothelial Cells; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Naphthalenes; Paxillin; Phosphorylation; Pyridines; ras Proteins; rhoA GTP-Binding Protein; RNA, Messenger; Terbinafine | 2006 |
Rho-kinase dependent organization of stress fibers and focal adhesions in cultured fibroblasts.
Topics: Actinin; Actins; Amides; Animals; Cell Line; Fibroblasts; Focal Adhesions; Green Fluorescent Proteins; Humans; Intracellular Signaling Peptides and Proteins; Mice; Microscopy, Electron; Microscopy, Fluorescence; NIH 3T3 Cells; Paxillin; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; rho-Associated Kinases; Stress Fibers; Transfection | 2007 |
RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3.
Topics: Amides; Animals; Benzoquinones; Cell Line; Enzyme Inhibitors; Exocytosis; Focal Adhesion Kinase 1; Hydrochloric Acid; Hydrogen-Ion Concentration; Lactams, Macrocyclic; Opossums; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; rhoA GTP-Binding Protein; Rifabutin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Stress Fibers; Tyrosine | 2007 |
The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.
Topics: Actins; Amides; Aminoquinolines; Animals; Cell Adhesion; Cell Shape; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Focal Adhesions; Gene Expression; Mesangial Cells; Microtubules; Nocodazole; Paxillin; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Thrombospondin 1 | 2008 |
Altered adhesive structures and their relation to RhoGTPase activation in merlin-deficient Schwannoma.
Topics: Actins; Adenoviridae; Amides; Cells, Cultured; Enzyme Inhibitors; Focal Adhesions; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Humans; Immunohistochemistry; Microscopy, Confocal; Neurilemmoma; Neurofibromin 2; Paxillin; Peptides; Pyridines; rac1 GTP-Binding Protein; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; Schwann Cells; Transfection; Tumor Cells, Cultured | 2009 |
Roles of focal adhesions and fibronectin-mediated cohesion in proliferation of confluent fibroblasts.
Topics: Adult; Amides; Animals; Antibodies, Monoclonal; Antioxidants; Ascorbic Acid; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Matrix; Fibroblasts; Fibronectins; Focal Adhesions; Heterocyclic Compounds, 4 or More Rings; Humans; Integrin alpha5beta1; Middle Aged; Myosin Type II; Paxillin; Pyridines; rho-Associated Kinases; Stress Fibers; Transforming Growth Factor beta1; Vinculin | 2009 |
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.
Topics: Amides; Animals; Cells, Cultured; Extracellular Matrix; Fibroblasts; Fibronectins; Focal Adhesions; Heterocyclic Compounds, 4 or More Rings; Mice; Myosin Type II; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Structure-Activity Relationship; Vinculin | 2010 |
Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography.
Topics: Actin Cytoskeleton; Amides; Animals; Cell Line; Cryoelectron Microscopy; Fibroblasts; Focal Adhesions; Integrins; Microscopy, Fluorescence; Models, Molecular; Particle Size; Paxillin; Protein Kinase Inhibitors; Pyridines; Rats; rho-Associated Kinases; Stress Fibers; Tomography; Vinculin | 2010 |
The effect of lysophosphatidic acid and Rho-associated kinase patterning on adhesion of dental pulp cells.
Topics: Adult; Amides; Cell Movement; Cells, Cultured; Dental Pulp; Focal Adhesion Kinase 1; Focal Adhesions; Humans; Lysophospholipids; Paxillin; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Tyrosine; Young Adult | 2011 |
Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells.
Topics: Actomyosin; Amides; Aqueous Humor; Blotting, Western; Cell Line, Transformed; Cell-Matrix Junctions; Collagen; Focal Adhesion Protein-Tyrosine Kinases; Gels; Humans; Inhibitory Concentration 50; Myosin-Light-Chain Phosphatase; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stress Fibers; Trabecular Meshwork; Vinculin | 2011 |
γ-Actin regulates cell migration and modulates the ROCK signaling pathway.
Topics: Actins; Amides; Base Sequence; Cell Line; Cell Movement; Cell Polarity; Focal Adhesions; Gene Knockdown Techniques; Humans; Models, Biological; Myosin Light Chains; Paxillin; Phosphorylation; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Wound Healing | 2011 |
Caffeine inhibits migration in glioma cells through the ROCK-FAK pathway.
Topics: Amides; Animals; Blotting, Western; Caffeine; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Glioma; Humans; Microscopy, Fluorescence; Myosin Light Chains; Paxillin; Phosphorylation; Pyridines; Rats; rho-Associated Kinases; Signal Transduction; Time Factors | 2014 |