Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and papaverine

y 27632 has been researched along with papaverine in 4 studies

Compound Research Comparison

Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010)
(y 27632)		Studies
(papaverine)		Trials
(papaverine)		Recent Studies (post-2010) (papaverine)
1,92438916,027305355

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)papaverine (IC50)
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10ARattus norvegicus (Norway rat)0.076
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)2.3
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)8.8
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)1.7
Bile salt export pumpHomo sapiens (human)10
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)1.6
Cytochrome P450 2C19Homo sapiens (human)0.762
Serine hydroxymethyltransferase, mitochondrialHomo sapiens (human)2.6915
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)9
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.4
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)7.2444
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)1.03
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)9
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)0.697
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Rattus norvegicus (Norway rat)0.036
Phosphodiesterase Sus scrofa (pig)0.62
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)0.07

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Domokos, D; Falkay, G; Fülöp, F; Gáspár, R1
Chiba, Y; Misawa, M; Sakai, H1
Chiba, Y; Ishii, Y; Kitamura, S; Sugiyama, Y1
Didion, SP; Faraci, FM; Mathur, S; Ryan, MJ; Sigmund, CD1

Other Studies

4 other study(ies) available for y 27632 and papaverine

ArticleYear
Effects of newly synthetized isoquinoline derivatives on rat uterine contractility and ROCK II activity.
    Bioorganic & medicinal chemistry letters, 2018, 02-01, Volume: 28, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Female; Isoquinolines; Molecular Structure; Pregnancy; Protein Kinase Inhibitors; Rats; rho-Associated Kinases; Structure-Activity Relationship; Uterine Contraction

2018
Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats.
    British journal of pharmacology, 2001, Volume: 133, Issue:6

    Topics: Acetylcholine; Amides; Animals; Antigens; Biological Transport; Bronchi; Bronchial Hyperreactivity; Dose-Response Relationship, Drug; Enzyme Inhibitors; Muscle Contraction; Muscle, Smooth; Papaverine; Pyridines; Rats; Rats, Wistar; rhoA GTP-Binding Protein; Time Factors; Vasodilator Agents

2001
Activation of rho is involved in the mechanism of hydrogen-peroxide-induced lung edema in isolated perfused rabbit lung.
    Microvascular research, 2001, Volume: 62, Issue:2

    Topics: Amides; Animals; Blood Pressure; Capillaries; Capillary Permeability; Enzyme Inhibitors; Hydrogen Peroxide; Hydrostatic Pressure; In Vitro Techniques; Lung; Male; Organ Size; Oxidants; Papaverine; Perfusion; Pulmonary Edema; Pyridines; Rabbits; rho GTP-Binding Proteins; Vasodilator Agents

2001
Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Amides; Angiotensin II; Animals; Aorta; Carotid Arteries; Infusion Pumps, Implantable; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitroprusside; Papaverine; Phenylephrine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Sequence Deletion; Serotonin; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2004