Page last updated: 2024-09-03

y 27632 and paclitaxel

y 27632 has been researched along with paclitaxel in 13 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(paclitaxel)
Trials
(paclitaxel)
Recent Studies (post-2010) (paclitaxel)
1,924389131,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (61.54)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Barrett, M; Burnitz, MC; Dipierro, C; Eto, M; Gibson, JJ; Myers, C; Phelps, C; Read, P; Somlyo, AP; Somlyo, AV1
Niggli, V1
Giehl, K; Goppelt-Struebe, M; Graness, A; Iwanciw, D; Ott, C1
Kharitonova, MA; Vasiliev, JM1
Adyshev, D; Bogatcheva, NV; Mambetsariev, B; Moldobaeva, N; Verin, AD1
Hordichok, AJ; Steyger, PS1
Blum, M; Mihatsch, J; Möller, W; Rösner, H; Wassermann, T1
Farber, DB; Gribanova, YE; Kitamura, E1
Balzer, EM; Boggs, AE; Hung, WC; Konstantopoulos, K; Martin, SS; Paul, CD; Stroka, KM; Tong, Z1
Dulin, N; Kach, J; Kregel, S; Ngam, C; Sandbo, N; Torr, E1
Chen, M; Duan, H; Jiang, Z; Miao, J; Sun, L; Wang, Y; Wu, M; Zhang, L; Zhang, S; Zhang, X; Zhu, X1
Ahmed, T; Auner, HW; Bozec, L; Dazzi, F; Enayati, M; Faull, PA; Ferreira, SA; Festy, F; Gentleman, E; Grigoriadis, AE; Haghighi, T; Kania, EM; Loaiza, S; Motwani, MS; Oommen, OP; Parzych, K; Salzlechner, C; Seymour, AJ; Snijders, AP; Taheem, DK; Varghese, OP; Yu, TTL1

Other Studies

13 other study(ies) available for y 27632 and paclitaxel

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:2

    Topics: Amides; Animals; Aorta, Thoracic; Cell Division; Cell Line; Drug Synergism; Enzyme Inhibitors; Humans; Hydroxamic Acids; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, SCID; Microscopy, Fluorescence; Myosin-Light-Chain Phosphatase; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Phosphoprotein Phosphatases; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2003
Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways.
    Journal of cell science, 2003, Mar-01, Volume: 116, Issue:Pt 5

    Topics: Amides; Androstadienes; Cell Movement; Colchicine; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Microtubules; Myosin Light Chains; Neutrophils; Oligopeptides; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Wortmannin

2003
Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Actins; Amides; Bacterial Proteins; Bacterial Toxins; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Colchicine; Connective Tissue Growth Factor; Cytochalasin D; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Nocodazole; Paclitaxel; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Stress, Mechanical; Thiazoles; Thiazolidines

2003
Length control is determined by the pattern of cytoskeleton.
    Journal of cell science, 2004, Apr-15, Volume: 117, Issue:Pt 10

    Topics: Actin Cytoskeleton; Actins; Amides; Animals; Cell Adhesion; Cell Shape; Cytoplasm; Cytoskeleton; Dogs; Embryo, Mammalian; Enzyme Inhibitors; Epithelial Cells; Fibroblasts; Mice; Microscopy, Fluorescence; Microscopy, Interference; Microtubules; Paclitaxel; Phenotype; Pyridines; Time Factors

2004
Involvement of microtubules, p38, and Rho kinases pathway in 2-methoxyestradiol-induced lung vascular barrier dysfunction.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:2

    Topics: 2-Methoxyestradiol; Actomyosin; Amides; Blood-Air Barrier; Cell Membrane Permeability; Endothelial Cells; Estradiol; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Microelectrodes; Microtubules; Models, Biological; Myosin-Light-Chain Kinase; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; rho-Associated Kinases; Tubulin

2007
Closure of supporting cell scar formations requires dynamic actin mechanisms.
    Hearing research, 2007, Volume: 232, Issue:1-2

    Topics: Actins; Amides; Animals; Anti-Bacterial Agents; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Death; Cicatrix; Colchicine; Cytochalasin D; Gentamicins; Hair Cells, Auditory; Immunohistochemistry; Keratins; Microscopy, Confocal; Microscopy, Electron, Transmission; Microtubules; Myosins; Paclitaxel; Pyridines; Rana catesbeiana; Saccule and Utricle; Thiazolidines; Time Factors; Tissue Culture Techniques; Tubulin Modulators; Wound Healing

2007
Attenuation of actinomyosinII contractile activity in growth cones accelerates filopodia-guided and microtubule-based neurite elongation.
    Brain research, 2007, Oct-24, Volume: 1176

    Topics: Actomyosin; Amides; Animals; Central Nervous System; Chick Embryo; Contractile Proteins; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibronectins; Growth Cones; Heterocyclic Compounds, 4 or More Rings; Laminin; Microtubules; Neural Pathways; Neurites; Neurogenesis; Nocodazole; Paclitaxel; Pseudopodia; Pyridines; rho GTP-Binding Proteins; Tubulin Modulators

2007
Regulation of retinoschisin secretion in Weri-Rb1 cells by the F-actin and microtubule cytoskeleton.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Actins; Amides; Blotting, Western; Cell Line, Tumor; Cytochalasin D; Cytoskeleton; Depsipeptides; Dibutyryl Cyclic GMP; Eye Proteins; Humans; Immunohistochemistry; Microtubules; Paclitaxel; Pyridines; Retinoschisis; Tubulin Modulators

2011
Physical confinement alters tumor cell adhesion and migration phenotypes.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:10

    Topics: Actins; Amides; Azepines; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cytoskeleton; Humans; Microtubules; Myosin-Light-Chain Kinase; Naphthalenes; Paclitaxel; Pyridines; rho-Associated Kinases; Tubulin Modulators

2012
Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2.
    The Journal of biological chemistry, 2013, May-31, Volume: 288, Issue:22

    Topics: Adaptor Proteins, Signal Transducing; Amides; Anilides; Benzamides; Cell Differentiation; Cells, Cultured; Colchicine; DNA-Binding Proteins; Enzyme Inhibitors; Formins; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Microtubules; Myofibroblasts; Oncogene Proteins, Fusion; Paclitaxel; Protein Transport; Pyridines; Serum Response Factor; Smad Proteins; Stress Fibers; Trans-Activators; Transforming Growth Factor beta; Tubulin Modulators

2013
Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:8

    Topics: Amides; Angiogenesis Inhibitors; Animals; Blood Vessels; Cell Cycle; Cell Movement; Cell Proliferation; Chickens; Chorioallantoic Membrane; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Drugs, Chinese Herbal; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Mice, Nude; Microtubules; Neovascularization, Pathologic; Neovascularization, Physiologic; Paclitaxel; Podophyllotoxin; Pyridines; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays

2013
Bi-directional cell-pericellular matrix interactions direct stem cell fate.
    Nature communications, 2018, 10-03, Volume: 9, Issue:1

    Topics: Amides; Cell Communication; Cell Lineage; Cell-Matrix Junctions; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Mesenchymal Stem Cells; Paclitaxel; Pyridines; Stem Cells

2018