y 27632 has been researched along with nsc 23766 in 17 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (nsc 23766) | Trials (nsc 23766) | Recent Studies (post-2010) (nsc 23766) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 12 | 0 | 8 |
| 1,924 | 3 | 891 | 200 | 0 | 147 |
| Protein | Taxonomy | y 27632 (IC50) | nsc 23766 (IC50) |
|---|---|---|---|
| Ras-related C3 botulinum toxin substrate 1 | Mus musculus (house mouse) | 6.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 13 (76.47) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Giehl, K; Goppelt-Struebe, M; Graness, A | 1 |
| Baba, TT; Miyazaki, T; Nemoto, TK; Oida, S | 1 |
| Chen, YH; Longo, FM; Lu, Q; Massa, SM; Zhou, H | 1 |
| Ackermann, N; Heesemann, J; Wölke, S | 1 |
| Guo, YM; Hirokawa, M; Komatsuda, A; Michishita, Y; Nara, M; Nunomura, W; Sawada, K; Tagawa, H; Takahashi, M; Takahashi, N; Takakuwa, Y; Ubukawa, K | 1 |
| Campbell, WB; Nithipatikom, K; Tang, AT | 1 |
| Harata, A; Ihara, S; Matsuzaki, T; Nishikawa, A | 1 |
| Bredow, M; Brünnert, D; Ehrhardt, J; Goyal, P; Piccenini, S; Zygmunt, M | 1 |
| Hou, YY; Liu, JG; Liu, Y; Wang, J; Wang, YH; Xi, T | 1 |
| Bachelot-Loza, C; Egot, M; Gaussem, P; Kauskot, A; Lasne, D | 1 |
| Cho, YK; Hwang, H; Kim, EK; Park, J; Suh, PG | 1 |
| Arevalos, CA; Berg, JM; Godfrey, EL; Grande-Allen, KJ; Nguyen, JM; Rupert, AA; Walborn, AT | 1 |
| Hwang, C; Jang, H; Jeong, GS; Kim, BS; Park, S; Park, Y | 1 |
| Bentzer, P; Dolinina, J; Öberg, CM; Rippe, A | 1 |
| Iida, H; Kojima, A; Kozawa, O; Nakashima, D; Tachi, J; Tanabe, K | 1 |
| Bureau, C; Chalin, D; Golushko, I; Kissa, K; Lorman, V; Parmeggiani, A; Poullet, N; Rochal, S; Travnickova, J | 1 |
17 other study(ies) available for y 27632 and nsc 23766
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression.
Topics: Actins; Amides; Aminoquinolines; Animals; Cell Adhesion; Cell Shape; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Focal Adhesions; Gene Expression; Mesangial Cells; Microtubules; Nocodazole; Paxillin; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Thrombospondin 1 | 2008 |
Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway.
Topics: Alkaline Phosphatase; Amides; Aminoquinolines; Animals; Bone Morphogenetic Protein 2; Cell Differentiation; Cells, Cultured; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Muscle Fibers, Skeletal; Myoblasts, Skeletal; Myogenin; Osteoblasts; Polyisoprenyl Phosphates; Protein Kinase Inhibitors; Pyridines; Pyrimidines; rac GTP-Binding Proteins; Recombinant Proteins; rho-Associated Kinases; Sesquiterpenes; Signal Transduction; Simvastatin | 2008 |
Signaling through Rho GTPase pathway as viable drug target.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Aminoquinolines; Anilides; Animals; Benzamides; Cardiovascular Diseases; Humans; Lung Diseases; Neoplasms; Nervous System Diseases; Protein Kinase Inhibitors; Pyridines; Pyrimidines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2009 |
The Yersinia enterocolitica type 3 secretion system (T3SS) as toolbox for studying the cell biological effects of bacterial Rho GTPase modulating T3SS effector proteins.
Topics: Amides; Aminoquinolines; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cytoskeleton; Enzyme Inhibitors; HeLa Cells; Humans; Pyridines; Pyrimidines; rho GTP-Binding Proteins; Yersinia enterocolitica; Yersinia Infections | 2011 |
Enucleation of human erythroblasts involves non-muscle myosin IIB.
Topics: Amides; Aminoquinolines; Cells, Cultured; Cytokinesis; Enzyme Inhibitors; Erythroblasts; Erythroid Precursor Cells; Erythropoiesis; Green Fluorescent Proteins; Heterocyclic Compounds, 4 or More Rings; Humans; Microfilament Proteins; Myosins; Nonmuscle Myosin Type IIA; Nonmuscle Myosin Type IIB; Peptide Fragments; Protein Isoforms; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; rho-Associated Kinases | 2012 |
ROCK1 feedback regulation of the upstream small GTPase RhoA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; ADP Ribose Transferases; Amides; Aminoquinolines; Botulinum Toxins; Cell Line, Tumor; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Humans; Male; Prostatic Neoplasms; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; T-Lymphoma Invasion and Metastasis-inducing Protein 1 | 2012 |
The cell sorting process of Xenopus gastrula cells involves the acto-myosin system and TGF-β signaling.
Topics: Actomyosin; Amides; Aminoquinolines; Animals; Body Patterning; Cartilage; Cell Aggregation; Cell Movement; Embryonic Development; Gastrula; Mesoderm; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Xenopus | 2013 |
Cytokine IL-6 secretion by trophoblasts regulated via sphingosine-1-phosphate receptor 2 involving Rho/Rho-kinase and Rac1 signaling pathways.
Topics: Amides; Aminoquinolines; Cell Line; Chromones; Cycloheximide; Dactinomycin; Female; Humans; Interleukin-6; Lysophospholipids; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Pyrazoles; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Receptors, Lysosphingolipid; rho GTP-Binding Proteins; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Trophoblasts | 2013 |
The small GTPase RhoA, but not Rac1, is essential for conditioned aversive memory formation through regulation of actin rearrangements in rat dorsal hippocampus.
Topics: Actins; Amides; Aminoquinolines; Animals; Avoidance Learning; Hippocampus; Male; Memory; Microinjections; Morphine; Naloxone; Polymerization; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Substance Withdrawal Syndrome | 2013 |
Biphasic myosin II light chain activation during clot retraction.
Topics: Actin Cytoskeleton; Actomyosin; Amides; Aminoquinolines; Azepines; Blood Platelets; Cells, Cultured; Clot Retraction; Humans; Kinetics; Myosin Light Chains; Myosin Type II; Myosin-Light-Chain Kinase; Naphthalenes; Phosphorylation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Wound Healing | 2013 |
RhoA and Rac1 play independent roles in lysophosphatidic acid-induced ovarian cancer chemotaxis.
Topics: ADP Ribose Transferases; Amides; Aminoquinolines; Botulinum Toxins; Cell Line, Tumor; Chemotaxis; Enzyme Inhibitors; Female; Guanine Nucleotide Exchange Factors; Humans; Lysophospholipids; Microfluidic Analytical Techniques; Ovarian Neoplasms; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; rho-Associated Kinases; rhoA GTP-Binding Protein | 2014 |
Regulation of valve endothelial cell vasculogenic network architectures with ROCK and Rac inhibitors.
Topics: Actins; Amides; Aminoquinolines; Animals; Aortic Valve; Cell Communication; Cell Movement; Cell Transdifferentiation; Endothelial Cells; Image Processing, Computer-Assisted; Immunohistochemistry; Platelet Endothelial Cell Adhesion Molecule-1; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; rho-Associated Kinases; Swine; Wound Healing | 2015 |
Directional migration of mesenchymal stem cells under an SDF-1α gradient on a microfluidic device.
Topics: Amides; Aminoquinolines; Benzylamines; Cell Movement; Chemokine CXCL12; Cyclams; Heterocyclic Compounds; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Lab-On-A-Chip Devices; Mesenchymal Stem Cells; Microscopy, Confocal; Pyridines; Pyrimidines; rac GTP-Binding Proteins; rho GTP-Binding Proteins; Signal Transduction | 2017 |
Glomerular hyperpermeability after acute unilateral ureteral obstruction: effects of Tempol, NOS, RhoA, and Rac-1 inhibition.
Topics: Amides; Aminoquinolines; Animals; Antioxidants; Arterial Pressure; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Heart Rate; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Proteinuria; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats, Sprague-Dawley; Reactive Oxygen Species; rho GTP-Binding Proteins; rho-Associated Kinases; Spin Labels; Time Factors; Ureteral Obstruction | 2018 |
Limitation by Rho-kinase and Rac of transforming growth factor-β-induced interleukin-6 release from astrocytes.
Topics: Amides; Aminoquinolines; Animals; Astrocytes; Interleukin-6; Mice; Phosphorylation; Pyridines; Pyrimidines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta | 2019 |
Mechanical instabilities of aorta drive blood stem cell production: a live study.
Topics: Amides; Aminoquinolines; Animals; Animals, Genetically Modified; Aorta; Embryo, Nonmammalian; Endothelial Cells; Hematopoiesis; Hematopoietic Stem Cells; Microscopy, Fluorescence; Pyridines; Pyrimidines; Time-Lapse Imaging; Zebrafish | 2020 |