Page last updated: 2024-09-03

y 27632 and nitroarginine

y 27632 has been researched along with nitroarginine in 8 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(nitroarginine)
Trials
(nitroarginine)
Recent Studies (post-2010) (nitroarginine)
1,92438913,93511175

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)nitroarginine (IC50)
Nitric oxide synthase, endothelialBos taurus (cattle)1.2
Nitric oxide synthase, endothelialHomo sapiens (human)0.38
Nitric oxide synthase, brainHomo sapiens (human)1.265
Nitric oxide synthase, brain Rattus norvegicus (Norway rat)4.12
Nitric oxide synthase, inducibleMus musculus (house mouse)0.5
Nitric oxide synthase, inducibleHomo sapiens (human)6.2
Nitric oxide synthase, brainMus musculus (house mouse)0.5

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boer, C; de Lange, JJ; Scheffer, GJ; Sipkema, P; van der Linden, PJ; Westerhof, N1
Begaye, M; Carter, RW; Kanagy, NL1
Büyükafsar, K; Levent, A1
Baumbach, GL; Didion, SP; Faraci, FM; Lynch, CM1
Abman, SH; Grover, TR; Parker, TA; Roe, G1
Bagcivan, I; Berkan, O; Disli, OM; Durmus, N; Ozdemir, E; Parlak, A1
Enouri, S; Johnson, R; Monteith, G1
Ishikawa, T; Sahara, Y; Saito, SY1

Other Studies

8 other study(ies) available for y 27632 and nitroarginine

ArticleYear
RhoA/Rho kinase and nitric oxide modulate the agonist-induced pulmonary artery diameter response time.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:3

    Topics: Acetylcholine; Amides; Animals; Electrophysiology; Endothelium, Vascular; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Male; Microelectrodes; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rats; Rats, Wistar; Renal Artery; rho-Associated Kinases; Sensitivity and Specificity; Vasoconstriction; Vasodilation

2002
Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4

    Topics: Adrenergic alpha-Agonists; Amides; Animals; Aorta; Brimonidine Tartrate; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Protein Serine-Threonine Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoconstriction

2002
Expression of Rho-kinase (ROCK-1 and ROCK-2) and its substantial role in the contractile activity of the sheep ureter.
    British journal of pharmacology, 2004, Volume: 143, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Aorta; Atropine; Blotting, Western; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Guanethidine; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Sheep; Tetrodotoxin; Ureter; Vasoconstrictor Agents; Vasodilator Agents

2004
Impaired endothelium-dependent responses and enhanced influence of Rho-kinase in cerebral arterioles in type II diabetes.
    Stroke, 2005, Volume: 36, Issue:2

    Topics: Acetylcholine; Amides; Animals; Blood Glucose; Body Weight; Cerebral Arteries; Cerebrovascular Circulation; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Polyethylene Glycols; Protein Serine-Threonine Kinases; Pyridines; Reactive Oxygen Species; rho-Associated Kinases; Superoxide Dismutase; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2005
Rho kinase activation maintains high pulmonary vascular resistance in the ovine fetal lung.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 291, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Lung; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pregnancy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pulmonary Circulation; Pyridines; rho-Associated Kinases; Sheep; Signal Transduction; Vascular Resistance

2006
Rho-kinase inhibitors Y-27632 and fasudil prevent agonist-induced vasospasm in human radial artery.
    Canadian journal of physiology and pharmacology, 2009, Volume: 87, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Amides; Constriction, Pathologic; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Nitroarginine; Nitroprusside; Oxadiazoles; Protein Kinase Inhibitors; Pyridines; Quinoxalines; Radial Artery; Receptors, Calcium-Sensing; rho-Associated Kinases; Vasoconstriction; Vasodilation

2009
Characteristics of myogenic reactivity in isolated rat mesenteric veins.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:2

    Topics: Amides; Animals; Benzophenanthridines; Calcium; Calcium Channels, L-Type; Compliance; Endothelin-1; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide Synthase Type III; Nitroarginine; Norepinephrine; Pressure; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases

2011
Involvement of nitric oxide production in the impairment of skin blood flow response to local cooling in diabetic db/db mice.
    European journal of pharmacology, 2013, Nov-15, Volume: 720, Issue:1-3

    Topics: Adrenergic alpha-Antagonists; Amides; Animals; Cold Temperature; Diabetes Mellitus; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Protein Kinase Inhibitors; Pyridines; Regional Blood Flow; rho-Associated Kinases; Skin; Skin Temperature

2013