y 27632 has been researched along with ng-nitroarginine methyl ester in 24 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (ng-nitroarginine methyl ester) | Trials (ng-nitroarginine methyl ester) | Recent Studies (post-2010) (ng-nitroarginine methyl ester) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 12,640 | 117 | 2,342 |
| Protein | Taxonomy | y 27632 (IC50) | ng-nitroarginine methyl ester (IC50) |
|---|---|---|---|
| Neutrophil elastase | Homo sapiens (human) | 2.7 | |
| Nitric oxide synthase, endothelial | Homo sapiens (human) | 2.1 | |
| Nitric oxide synthase, brain | Homo sapiens (human) | 1.1167 | |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | 2.6 | |
| Nitric oxide synthase, inducible | Homo sapiens (human) | 8 | |
| Collagenase 3 | Homo sapiens (human) | 2.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 17 (70.83) | 29.6817 |
| 2010's | 6 (25.00) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Chrissobolis, S; Sobey, CG | 1 |
| Cellek, S; Moncada, S; Ralph, DJ; Rees, RW; Royle, M | 1 |
| Egashira, K; Inoue, S; Kaibuchi, K; Kataoka, C; Kitamoto, S; Koyanagi, M; Ni, W; Shimokawa, H; Takemoto, M; Takeshita, A; Usui, M | 1 |
| Ago, T; Fujishima, M; Ibayashi, S; Kamouchi, M; Kitazono, T; Ooboshi, H; Santa, N | 1 |
| Hartshorne, DJ; Isaka, N; Ito, M; Kureishi, Y; Moriki, N; Nakano, T; Okamoto, R; Onishi, K; Seko, T | 1 |
| Hosaka, K; Mizuno, R; Ohhashi, T | 1 |
| Hirooka, Y; Ito, K; Kaibuchi, K; Kimura, Y; Kishi, T; Shimokawa, H; Takeshita, A | 1 |
| Budzyn, K; Marley, PD; Sobey, CG | 1 |
| Budzyn, K; Chrissobolis, S; Marley, PD; Sobey, CG | 1 |
| Aaronson, PI; Leach, RM; Patel, R; Snetkov, VA; Thomas, GD; Ward, JP | 1 |
| Teixeira, CE; Webb, RC; Ying, Z | 1 |
| Jin, L; Palmer, T; Priviero, FB; Teixeira, CE; Webb, RC; Ying, Z | 1 |
| Chon, KH; Cupples, WA; Shi, Y; Wang, X | 1 |
| Ray, PE; Short, BL; Xie, H | 1 |
| Baxter, GF; Bower, HS; Hamid, SA | 1 |
| Ark, M; Büyükafşar, K; Cnar, MG; Erol, A; Kubat, H; Tiftik, RN; Ulker, S | 1 |
| Dhaese, I; Lefebvre, RA | 1 |
| Abe, S; Watabe, H; Yoshitomi, T | 1 |
| Braam, B; Chon, KH; Cupples, WA; Mitrou, N; Scully, CG | 1 |
| Alexandre, EC; Alves Junior, MJ; Antunes, E; Báu, FR; Calmasini, FB; Leiria, LO; Mónica, FZ; Silva, FH | 1 |
| Khin, PP; Sohn, UD; Zaw, TS | 1 |
| Islam, MZ; Miyamoto, A; Shiraishi, M; Van Dao, C | 1 |
| Bentzer, P; Dolinina, J; Öberg, CM; Rippe, A | 1 |
| Amore, F; Cellai, I; Cipriani, S; Comeglio, P; Danza, G; Filippi, S; Guarnieri, G; Maggi, M; Martinelli, S; Maseroli, E; Morelli, A; Raddi, C; Rapizzi, E; Rastrelli, G; Sarchielli, E; Vignozzi, L; Villanelli, F | 1 |
24 other study(ies) available for y 27632 and ng-nitroarginine methyl ester
| Article | Year |
|---|---|
Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: comparison with protein kinase C.
Topics: Amides; Animals; Basilar Artery; Blood Pressure; Cerebral Arteries; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; Species Specificity; Vasodilator Agents; Vasomotor System | 2001 |
Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum.
Topics: Amides; Animals; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle Relaxants, Central; NG-Nitroarginine Methyl Ester; Penis; Phenylephrine; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Synaptic Transmission; Vasoconstrictor Agents | 2001 |
Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats.
Topics: Actins; Amides; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Chemokine CCL2; Coronary Vessels; Enzyme Inhibitors; Hydralazine; Immunohistochemistry; Inflammation; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Muscle, Smooth; Myosins; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; rho-Associated Kinases; RNA, Messenger; Superoxide Dismutase; Tetrazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo.
Topics: Acetylcholine; Amides; Animals; Antihypertensive Agents; Basilar Artery; Calcium Channel Blockers; Calcium Channels; Chronic Disease; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; NG-Nitroarginine Methyl Ester; Nicardipine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2002 |
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Threonine | 2003 |
Rho-Rho kinase pathway is involved in the regulation of myogenic tone and pump activity in isolated lymph vessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Lymphatic System; Male; Muscle Tonus; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Okadaic Acid; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases; Vasoconstrictor Agents | 2003 |
Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition.
Topics: Amides; Animals; Blood Pressure; Enzyme Inhibitors; Hydralazine; Hypertension; Injections; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred WKY; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Solitary Nucleus | 2004 |
Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice.
Topics: Amides; Animals; Anticholesteremic Agents; Aorta, Thoracic; Cholesterol; Enzyme Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Lovastatin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Vasoconstriction | 2004 |
Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo.
Topics: Acetylcholine; Amides; Animals; Basilar Artery; Calcium Channel Blockers; Cerebrovascular Circulation; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Ovariectomy; Picolines; Potassium Channels; Protein Serine-Threonine Kinases; Pyrans; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Serotonin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2004 |
Sphingosylphosphorylcholine-induced vasoconstriction of pulmonary artery: activation of non-store-operated Ca2+ entry.
Topics: Amides; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Signaling; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 1; In Vitro Techniques; Lanthanum; Lysophospholipids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphorylcholine; Pulmonary Artery; Pyridines; Rats; Sphingosine; Thapsigargin; Type C Phospholipases; Vasoconstriction | 2005 |
Proerectile effects of the Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine (H-1152) in the rat penis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Blood Pressure; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitroprusside; Penis; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2005 |
Expression and functional role of the RhoA/Rho-kinase pathway in rat coeliac artery.
Topics: Amides; Animals; Blotting, Western; Celiac Artery; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Guanine Nucleotide Exchange Factors; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phenylephrine; Potassium; Protein Serine-Threonine Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Tubuloglomerular feedback-dependent modulation of renal myogenic autoregulation by nitric oxide.
Topics: Amides; Animals; Drug Synergism; Enzyme Inhibitors; Feedback, Physiological; Kidney; Kidney Tubules; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renal Circulation; Vasoconstriction | 2006 |
Rho-kinase contributes to hypoxia/reoxygenation-induced cerebral endothelial dysfunction.
Topics: Acetylcholine; Alkaloids; Amides; Animals; Benzophenanthridines; Cerebral Arteries; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Phenanthridines; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Superoxides; Triazenes; Vasodilation; Vasodilator Agents | 2006 |
Rho kinase activation plays a major role as a mediator of irreversible injury in reperfused myocardium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Androstadienes; Animals; Apoptosis; Cardiotonic Agents; Coronary Circulation; Cytoskeletal Proteins; Enzyme Activation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Microfilament Proteins; Multiprotein Complexes; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Wortmannin | 2007 |
Nitric oxide does not downregulate Rho-kinase (ROCK-2) expression in rat coronary endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Calcimycin; Cells, Cultured; Coronary Vessels; Down-Regulation; Endothelial Cells; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroglycerin; Nitroprusside; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; Sodium Nitrite; Triazenes | 2008 |
Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.
Topics: Adenine; Amides; Animals; Enzyme Activation; Gastric Fundus; Glyburide; Hydrogen Sulfide; In Vitro Techniques; Male; Marine Toxins; Mice; Muscle Relaxation; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; omega-Conotoxins; Oxazoles; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetrodotoxin | 2009 |
Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries.
Topics: Amides; Animals; Calcium; Ciliary Arteries; Dose-Response Relationship, Drug; Fluorophotometry; Indomethacin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pyridines; Rabbits; rho-Associated Kinases; Vasodilation | 2011 |
Detecting physiological systems with laser speckle perfusion imaging of the renal cortex.
Topics: Algorithms; Amides; Animals; Baroreflex; Blood Pressure; Enzyme Inhibitors; Feedback, Physiological; Heart Rate; Homeostasis; Image Processing, Computer-Assisted; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Lasers; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Perfusion Imaging; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Long-Evans; Renal Circulation; rho-Associated Kinases | 2013 |
Increased Rho-kinase-mediated prostate contractions associated with impairment of β-adrenergic-cAMP-signaling pathway by chronic nitric oxide deficiency.
Topics: Adenosine Triphosphate; Amides; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Prostate; Pyridines; Rats; rho-Associated Kinases; Signal Transduction | 2015 |
Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle.
Topics: 4-Aminopyridine; Amides; Animals; Atropine; Azepines; Benzophenanthridines; Bicuculline; Calcimycin; Drug Interactions; Electric Stimulation; Estrenes; Fluoxetine; Glyburide; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Ondansetron; Pyridines; Pyrrolidinones; Rats; Signal Transduction; Sulfonamides; Tetraethylammonium | 2017 |
Rho-kinase and the nitric oxide pathway modulate basilar arterial reactivity to acetylcholine and angiotensin II in streptozotocin-induced diabetic mice.
Topics: Acetylcholine; Amides; Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; rho-Associated Kinases; Streptozocin; Time Factors | 2017 |
Glomerular hyperpermeability after acute unilateral ureteral obstruction: effects of Tempol, NOS, RhoA, and Rac-1 inhibition.
Topics: Amides; Aminoquinolines; Animals; Antioxidants; Arterial Pressure; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Heart Rate; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Proteinuria; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats, Sprague-Dawley; Reactive Oxygen Species; rho GTP-Binding Proteins; rho-Associated Kinases; Spin Labels; Time Factors; Ureteral Obstruction | 2018 |
The regulatory effect of sex steroids on the RhoA/ROCK pathway in the rat distal vagina.
Topics: Androgens; Animals; Enzyme Inhibitors; Estradiol; Female; Humans; Letrozole; NG-Nitroarginine Methyl Ester; Nitroprusside; Ovariectomy; Rats; Rats, Sprague-Dawley; rho-Specific Guanine Nucleotide Dissociation Inhibitors; rhoA GTP-Binding Protein; Testosterone; Vagina | 2023 |