Page last updated: 2024-09-03

y 27632 and mln 8237

y 27632 has been researched along with mln 8237 in 2 studies

Compound Research Comparison

Studies (y 27632)	Trials (y 27632)	Recent Studies (post-2010) (y 27632)	Studies (mln 8237)	Trials (mln 8237)	Recent Studies (post-2010) (mln 8237)
1,924	3	891	246	43	236

Protein Interaction Comparison

Protein	Taxonomy	mln 8237 (IC50)
Aurora kinase A	Homo sapiens (human)	0.0088
Tyrosine-protein kinase Lck	Homo sapiens (human)	0.32
Gamma-aminobutyric acid receptor subunit alpha-1	Homo sapiens (human)	0.49
Ephrin type-A receptor 2	Homo sapiens (human)	0.048
Aurora kinase A	Mus musculus (house mouse)	0.001
Aurora kinase B	Homo sapiens (human)	0.5416
Inner centromere protein	Homo sapiens (human)	0.0011

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Jones, BC; Kelley, LC; Kozyreva, VK; Loskutov, YV; Marinak, KM; Pugacheva, EN; Smolkin, MB	1

Other Studies

2 other study(ies) available for y 27632 and mln 8237

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Dual Targeting of Mesenchymal and Amoeboid Motility Hinders Metastatic Behavior. Molecular cancer research : MCR, 2017, Volume: 15, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Amides; Animals; Aurora Kinase A; Azepines; Cell Line, Tumor; Cell Movement; Cortactin; Enzyme Inhibitors; Female; Humans; Mice, Inbred NOD; Molecular Targeted Therapy; Myosin Light Chains; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-vav; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; rho-Associated Kinases; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays	2017

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Dual Targeting of Mesenchymal and Amoeboid Motility Hinders Metastatic Behavior.

Molecular cancer research : MCR, 2017, Volume: 15, Issue:6

Topics: Adaptor Proteins, Signal Transducing; Amides; Animals; Aurora Kinase A; Azepines; Cell Line, Tumor; Cell Movement; Cortactin; Enzyme Inhibitors; Female; Humans; Mice, Inbred NOD; Molecular Targeted Therapy; Myosin Light Chains; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-vav; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; rho-Associated Kinases; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2017