Page last updated: 2024-09-03

y 27632 and ml 9

y 27632 has been researched along with ml 9 in 18 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(ml 9)
Trials
(ml 9)
Recent Studies (post-2010) (ml 9)
1,924389120011
1,9243891136016

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (77.78)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Cox, KJ; Gaj, A; Ghosh, I; Jester, BW; Shomin, CD1
Bradshaw, D; Murphy, C; Myers, CE; Ramos, S; Somlyo, AP; Somlyo, AV1
Bao, J; Kishi, H; Kohama, K1
Ai, S; Asai, T; Iguchi, A; Kanda, S; Koike, T; Kuzuya, M; Maeda, K; Shibata, T1
Jin, N; Li, L; Rhoades, RA; Swartz, DR; Wang, Z; Yancey, KW; Zhang, D1
Bao, J; Kohama, K; Liu, L; Nakamura, A; Oishi, K; Uchida, MK; Yamada, T1
Hashimoto, M; Kagota, S; Kubota, Y; Kunitomo, M; Nakamura, K; Nejime, N; Shinozuka, K; Takahashi, K; Tanaka, N; Yudo, K1
Shimoda, LA; Sylvester, JT; Weigand, L1
Koide, M; Nakayama, K; Obara, K; Uchino, M; Yamanaka, A1
Amobi, NI; Chung, IP; Smith, IC1
Connell, LE; Helfman, DM1
Ikeda, K; Kawada, N; Matsui, H; Nakajima, Y; Nakatani, K; Sakabe, M; Sakata, H; Yamagishi, T1
Hordichok, AJ; Steyger, PS1
Benoit, M; Cuerrier, CM; Gobeil, F; Grandbois, M; Guillemette, G1
Ding, G; Tang, YQ; Wang, XQ; Wang, YL; Wang, ZC; Zheng, YJ; Zhou, B1
Chung, T; Liu, WF; McWhorter, FY; Nguyen, P; Wang, T1
Khin, PP; Sohn, UD; Zaw, TS1

Other Studies

18 other study(ies) available for y 27632 and ml 9

ArticleYear
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Testing the promiscuity of commercial kinase inhibitors against the AGC kinase group using a split-luciferase screen.
    Journal of medicinal chemistry, 2012, Feb-23, Volume: 55, Issue:4

    Topics: Animals; Binding, Competitive; Catalytic Domain; Cell-Free System; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Databases, Factual; Genes, Reporter; Luciferases; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Recombinant Fusion Proteins; Structure-Activity Relationship

2012
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells.
    Biochemical and biophysical research communications, 2000, Mar-24, Volume: 269, Issue:3

    Topics: Amides; Animals; Azepines; Cattle; Cell Division; Cells, Cultured; Chemotaxis; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Physiologic; Phosphoprotein Phosphatases; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Inhibitory effects of ML-9, wortmannin, and Y-27632 on the chemotaxis of vascular smooth muscle cells in response to platelet-derived growth factor-BB.
    Journal of biochemistry, 2000, Volume: 128, Issue:5

    Topics: Amides; Androstadienes; Animals; Aorta; Azepines; Becaplermin; Cells, Cultured; Chemotaxis; Enzyme Inhibitors; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyridines; Rabbits; Wortmannin

2000
Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathways.
    Atherosclerosis, 2001, Volume: 155, Issue:2

    Topics: Amides; Animals; Aorta; Azepines; Cattle; Cell Adhesion; Cell Movement; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Tunica Media

2001
Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle.
    Journal of muscle research and cell motility, 2001, Volume: 22, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Antineoplastic Agents; Aorta; Azepines; Calcium; Colchicine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Male; Microtubules; Muscle Contraction; Muscle, Smooth, Vascular; Nocodazole; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents

2001
Role of the short isoform of myosin light chain kinase in the contraction of cultured smooth muscle cells as examined by its down-regulation.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Jul-09, Volume: 99, Issue:14

    Topics: Amides; Animals; Azepines; Cell Line; DNA, Antisense; Down-Regulation; Enzyme Inhibitors; Guinea Pigs; Intracellular Signaling Peptides and Proteins; Isoenzymes; Isometric Contraction; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases

2002
Myosin light chain kinase and Rho-kinase participate in P2Y receptor-mediated acceleration of permeability through the endothelial cell layer.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:3

    Topics: Adenosine Triphosphate; Amides; Azepines; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Dextrans; Endothelial Cells; Endothelium, Vascular; Fluorescein-5-isothiocyanate; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Myosin-Light-Chain Kinase; Protein Serine-Threonine Kinases; Pyridines; Pyridoxal Phosphate; Receptors, Purinergic P2; rho-Associated Kinases; Thionucleotides

2005
Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Azepines; Endothelin-1; Enzyme Inhibitors; Genistein; Hypoxia; Indoles; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Maleimides; Myosin-Light-Chain Kinase; Potassium Chloride; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Wistar; rho-Associated Kinases; src-Family Kinases; Staurosporine; Vasoconstriction

2006
Stretch-induced triphosphorylation of myosin light chain and myogenic tone in canine basilar artery.
    European journal of pharmacology, 2006, Mar-18, Volume: 534, Issue:1-3

    Topics: Amides; Animals; Azepines; Basilar Artery; Calcium; Calcium Channel Blockers; Dogs; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Naphthalenes; Nicardipine; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Reflex, Stretch; rho-Associated Kinases; Time Factors

2006
Attenuation of contractility in rat epididymal vas deferens by Rho kinase inhibitors.
    Autonomic & autacoid pharmacology, 2006, Volume: 26, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Animals; Azepines; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Norepinephrine; Potassium; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Purinergic P2 Receptor Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; rho-Associated Kinases; Vas Deferens

2006
Myosin light chain kinase plays a role in the regulation of epithelial cell survival.
    Journal of cell science, 2006, Jun-01, Volume: 119, Issue:Pt 11

    Topics: Amides; Azepines; Cell Line; Cell Line, Transformed; Cell Survival; Cells, Cultured; Epithelial Cells; Humans; Integrin beta1; Intracellular Signaling Peptides and Proteins; Myosin Type II; Myosin-Light-Chain Kinase; Naphthalenes; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction

2006
Rho kinase inhibitor Y27632 affects initial heart myofibrillogenesis in cultured chick blastoderm.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2007, Volume: 236, Issue:2

    Topics: Amides; Animals; Azepines; Blastoderm; Blotting, Western; Cell Adhesion; Chick Embryo; DNA Primers; Fluorescent Antibody Technique, Indirect; Heart; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Muscle Development; Myosin-Light-Chain Kinase; Protein Serine-Threonine Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases

2007
Closure of supporting cell scar formations requires dynamic actin mechanisms.
    Hearing research, 2007, Volume: 232, Issue:1-2

    Topics: Actins; Amides; Animals; Anti-Bacterial Agents; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Death; Cicatrix; Colchicine; Cytochalasin D; Gentamicins; Hair Cells, Auditory; Immunohistochemistry; Keratins; Microscopy, Confocal; Microscopy, Electron, Transmission; Microtubules; Myosins; Paclitaxel; Pyridines; Rana catesbeiana; Saccule and Utricle; Thiazolidines; Time Factors; Tissue Culture Techniques; Tubulin Modulators; Wound Healing

2007
Real-time monitoring of angiotensin II-induced contractile response and cytoskeleton remodeling in individual cells by atomic force microscopy.
    Pflugers Archiv : European journal of physiology, 2009, Volume: 457, Issue:6

    Topics: Actins; Amides; Angiotensin II; Azepines; Cell Line; Cell Size; Cytological Techniques; Cytoskeleton; Elastic Modulus; Heterocyclic Compounds, 4 or More Rings; Humans; Kidney; Microscopy, Atomic Force; Microscopy, Confocal; Muscle Contraction; Pyridines; Receptor, Angiotensin, Type 1

2009
Effect of serum from patients with severe acute pancreatitis on vascular endothelial permeability.
    Pancreas, 2013, Volume: 42, Issue:4

    Topics: Actins; Amides; Antigens, CD; Azepines; Cadherins; Capillary Permeability; Case-Control Studies; Endothelial Cells; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Myosin-Light-Chain Kinase; Pancreatitis; Pyridines; rhoA GTP-Binding Protein

2013
Modulation of macrophage phenotype by cell shape.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-22, Volume: 110, Issue:43

    Topics: Amides; Animals; Arginase; Azepines; Biomarkers; Cell Polarity; Cell Shape; Cells, Cultured; Cytochalasin D; Cytokines; Doxorubicin; Female; Flow Cytometry; Immunophenotyping; Inflammation Mediators; Interferon-gamma; Interleukin-13; Interleukin-4; Lectins, C-Type; Lipopolysaccharides; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Myosin-Light-Chain Kinase; Pyridines; Receptors, Cell Surface

2013
Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle.
    Pharmacology, 2017, Volume: 99, Issue:5-6

    Topics: 4-Aminopyridine; Amides; Animals; Atropine; Azepines; Benzophenanthridines; Bicuculline; Calcimycin; Drug Interactions; Electric Stimulation; Estrenes; Fluoxetine; Glyburide; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Ondansetron; Pyridines; Pyrrolidinones; Rats; Signal Transduction; Sulfonamides; Tetraethylammonium

2017