Page last updated: 2024-09-03

y 27632 and lysophosphatidic acid

y 27632 has been researched along with lysophosphatidic acid in 35 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(lysophosphatidic acid)
Trials
(lysophosphatidic acid)
Recent Studies (post-2010) (lysophosphatidic acid)
1,92438911,950171,116

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)lysophosphatidic acid (IC50)
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.4998
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2Homo sapiens (human)0.4709

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's18 (51.43)29.6817
2010's17 (48.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Acevedo, J; Field, T; Moessner, P; Svoboda, KK1
Gilmont, RR; Hirano, S; Shelden, EA1
Hashimoto, T; Momose, K; Ohata, H1
Dash, PK; Moody, M; Moore, AN; Orsi, SA1
Crow, T; Dash, PK; Tian, LM; Xue-Bian, JJ1
Funfar, MR; Korpi, NL; McCoy, AC; Olmschenk, SM; Provost, JJ; Thronson, HL; Wallert, MA1
Hashimoto, T; Honda, K; Momose, K; Ohata, H1
Aaronson, PI; Leach, RM; Patel, R; Snetkov, VA; Thomas, GD; Ward, JP1
Beaudry, C; Berens, M; Kwan, A; Nakada, M; Rutka, JT; Rutten, F; Salhia, B1
Bertagnolli, MM; Carothers, AM; Hunt, DH; Javid, SH; Moran, AE; Redston, M1
Hosoya, H; Inoue, N; Kinoshita, N; Miyake, Y; Nishimura, K; Yonemura, S1
Hirakawa, M; Ito, Y; Karashima, Y; Kimura, C; Oike, M; Watanabe, M1
Grönberg, M; Janson, ET; Oberg, KE; Saras, J; Stridsberg, M1
Dressel, L; Grez, M; Henschler, R; Jaganathan, BG; Ruester, B; Seifried, E; Stein, S1
Ly, L; Ma, L; Petroll, WM; Vishwanath, M1
Yin, J; Yu, FS1
Endo, M; Hatanaka, Y; Hirai, S; Ohnami, S; Uesaka, N; Yamamoto, N; Yamashita, T1
Grinnell, F; Ho, CH; Rhee, S1
Cheng, L; Cheng, R; Hu, T; Shao, MY; Wang, FM; Yang, H; Zhou, XD2
Dixon, SJ; Lapierre, DM; Pereverzev, A; Shugg, RP; Sims, SM; Spencer, M; Tanabe, N1
Boergermann, C; Jakobs, KH; Lümmen, G; Rübben, H; Sanders, H; Schmidt, M; vom Dorp, F1
Adelstein, RS; Kim, JH1
He, C; Huang, ZH; Wang, Y; Yuan, XB1
Jin, T; Li, L; Liu, L; Ng, DS; Tam, L1
Cho, KH; Han, JW; Jeong, KJ; Kang, J; Kim, YK; Lee, HY; Lee, J; Park, CG; Park, SY; Sohn, JS1
Dai, K; Fu, Y; Geng, Y; Lui, PP; Shi, Y; Tang, T; Tong, W; Zhang, X1
Biechler, S; Dean, D; Goodwin, RL; Junor, L; Li, J; Potts, JD; Tan, H; Yost, MJ1
Li, Y; Liu, M; Qin, J; Ruan, Q; Yu, Y; Zhang, Z1
Cho, YK; Hwang, H; Kim, EK; Park, J; Suh, PG1
Liu, Y; Ma, T; Tsai, AC; Yuan, X1
Cheng, L; Cheng, R; Hu, T; Pan, HY; Qian, YY; Shao, MY; Xu, J; Yang, H1
Furukawa, S; Handa, H; Hashimoto, A; Hashimoto, S; Mikami, S; Oikawa, T; Okada, Y; Onodera, Y; Oya, M; Sabe, H; Sugino, H; Yoshikawa, A1
Bicker, G; Scheiblich, H1

Other Studies

35 other study(ies) available for y 27632 and lysophosphatidic acid

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
ROCK inhibitor (Y27632) increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2004, Volume: 229, Issue:3

    Topics: Actins; Amides; Animals; Annexin A5; Apoptosis; Caspase 3; Caspases; Chick Embryo; Collagen; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium, Corneal; Extracellular Matrix; Focal Adhesion Protein-Tyrosine Kinases; Lysophospholipids; Microscopy, Confocal; Models, Biological; Organ Culture Techniques; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Time Factors; Tyrosine

2004
HSP27 regulates fibroblast adhesion, motility, and matrix contraction.
    Cell stress & chaperones, 2004, Volume: 9, Issue:1

    Topics: Actins; Amides; Animals; Becaplermin; Blotting, Western; Cell Adhesion; Cell Division; Cell Line; Cell Movement; Cell Shape; Collagen; DNA, Antisense; DNA, Complementary; Extracellular Matrix; Fibroblasts; Genetic Vectors; Heat-Shock Proteins; Lysophospholipids; Mice; Microscopy, Fluorescence; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyridines; Transfection

2004
Itch-scratch responses induced by lysophosphatidic acid in mice.
    Pharmacology, 2004, Volume: 72, Issue:1

    Topics: Amides; Animals; Antipruritics; Capsaicin; Injections, Intradermal; Intracellular Signaling Peptides and Proteins; Ketotifen; Lysophospholipids; Mice; Mice, Inbred ICR; Protein Serine-Threonine Kinases; Pruritus; Pyridines; Rats; rho-Associated Kinases

2004
A role for hippocampal Rho-ROCK pathway in long-term spatial memory.
    Biochemical and biophysical research communications, 2004, Sep-24, Volume: 322, Issue:3

    Topics: Amides; Animals; Enzyme Activation; Enzyme Inhibitors; Hippocampus; Infusions, Parenteral; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Male; Memory; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Long-Evans; rho GTP-Binding Proteins; rho-Associated Kinases; Space Perception

2004
Rho/ROCK and Cdk5 effects on phosphorylation of a beta-thymosin repeat protein in Hermissenda.
    Biochemical and biophysical research communications, 2004, Oct-15, Volume: 323, Issue:2

    Topics: Amides; Animals; Butyrophenones; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Microfilament Proteins; Mollusca; Nervous System; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Thymosin

2004
Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway.
    Cellular signalling, 2005, Volume: 17, Issue:2

    Topics: Amides; Animals; Butadienes; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Lysophospholipids; MAP Kinase Kinase 1; Nitriles; Phenylephrine; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Pyridines; Receptors, Adrenergic, alpha; Receptors, G-Protein-Coupled; rho-Associated Kinases; Signal Transduction; Sodium-Hydrogen Exchangers; Transfection

2005
Lysophosphatidic acid induces histamine release from mast cells and skin fragments.
    Pharmacology, 2005, Volume: 75, Issue:1

    Topics: Amides; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gallic Acid; Histamine Release; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ionophores; Lysophospholipids; Male; Mast Cells; Mice; Mice, Inbred ICR; Peritoneum; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Skin; Species Specificity; Time Factors

2005
Sphingosylphosphorylcholine-induced vasoconstriction of pulmonary artery: activation of non-store-operated Ca2+ entry.
    Cardiovascular research, 2005, Oct-01, Volume: 68, Issue:1

    Topics: Amides; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Signaling; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 1; In Vitro Techniques; Lanthanum; Lysophospholipids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phosphorylcholine; Pulmonary Artery; Pyridines; Rats; Sphingosine; Thapsigargin; Type C Phospholipases; Vasoconstriction

2005
Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1.
    Cancer research, 2005, Oct-01, Volume: 65, Issue:19

    Topics: Actins; Amides; Astrocytoma; Cell Line, Tumor; Cell Movement; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Mutation; Neoplasm Invasiveness; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; rac1 GTP-Binding Protein; rho-Associated Kinases; Transfection

2005
Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.
    Experimental cell research, 2006, Feb-15, Volume: 312, Issue:4

    Topics: Actin Depolymerizing Factors; Actomyosin; Adenomatous Polyposis Coli Protein; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cadherins; Calcium; Cardiac Myosins; Celecoxib; Cell Adhesion; Egtazic Acid; Enterocytes; ErbB Receptors; Focal Adhesion Kinase 2; GTP-Binding Protein alpha Subunits, G12-G13; Intestinal Mucosa; Intestine, Small; Lysophospholipids; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinase 1; Muscle Contraction; Muscle Relaxants, Central; Myosin Light Chains; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Quinazolines; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Sulfonamides; Tyrphostins; Up-Regulation

2006
Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation.
    Experimental cell research, 2006, May-15, Volume: 312, Issue:9

    Topics: Actomyosin; Adherens Junctions; Amides; Animals; Cell Adhesion Molecules; Cell Line; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Dogs; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Lysophospholipids; Membrane Proteins; Mice; Microscopy, Electron, Transmission; Myosin Type II; Nonmuscle Myosin Type IIB; Occludin; Platelet-Derived Growth Factor; Pyridines; Rats; rho GTP-Binding Proteins; RNA, Small Interfering; Tight Junctions; Vinculin

2006
Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Actins; Amides; Animals; Bucladesine; Carbazoles; Cattle; Cell Membrane; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Pyrroles; rho-Associated Kinases; Theophylline; Trachea

2007
Somatostatin induces rapid contraction of neuroendocrine cells.
    FEBS letters, 2007, May-15, Volume: 581, Issue:10

    Topics: Actin Cytoskeleton; Amides; Cell Line, Tumor; Cell Shape; Cell Survival; Chromogranin A; Colforsin; Humans; Lysophospholipids; Neurosecretion; Neurosecretory Systems; Pyridines; Secretory Vesicles; Somatostatin; Time Factors

2007
Rho inhibition induces migration of mesenchymal stromal cells.
    Stem cells (Dayton, Ohio), 2007, Volume: 25, Issue:8

    Topics: Actin Cytoskeleton; Amides; Cell Movement; Cells, Cultured; Chemotaxis; Cytoskeleton; Humans; Lysophospholipids; Mesenchymal Stem Cells; Pyridines; Receptors, Lysophosphatidic Acid; rhoA GTP-Binding Protein; Stromal Cells

2007
Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation.
    Eye & contact lens, 2008, Volume: 34, Issue:1

    Topics: Amides; Biomechanical Phenomena; Cell Movement; Cells, Cultured; Corneal Stroma; Culture Media, Serum-Free; Enzyme Inhibitors; Fibroblasts; Humans; Image Processing, Computer-Assisted; Lysophospholipids; Pyridines; rho-Associated Kinases

2008
Rho kinases regulate corneal epithelial wound healing.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:2

    Topics: Adherens Junctions; Amides; beta Catenin; Blotting, Western; Cadherins; Cell Adhesion; Cell Line, Transformed; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Epithelial Cells; Epithelium, Corneal; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Membrane Proteins; Myosin-Light-Chain Phosphatase; Occludin; Phosphorylation; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Stress, Mechanical; Tight Junctions; Wound Healing

2008
Role of RhoA in activity-dependent cortical axon branching.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-10, Volume: 28, Issue:37

    Topics: Amides; Animals; Animals, Newborn; Axons; Bacterial Proteins; Electroporation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Humans; Luminescent Proteins; Lysophospholipids; Microscopy, Confocal; Neurons; Occipital Lobe; Organ Culture Techniques; Pyridines; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin

2008
Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis.
    Experimental cell research, 2010, Jan-15, Volume: 316, Issue:2

    Topics: Actins; Amides; Cell Aggregation; Cell Culture Techniques; Cell Line, Transformed; Cell Movement; Cell Shape; Collagen; Enzyme Inhibitors; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Male; Myosin Type II; Oncogene Protein p21(ras); Platelet-Derived Growth Factor; Pyridines; rho-Associated Kinases; Serum; Sphingosine; Vinculin

2010
Roles of lysophosphatidic acid and the Rho-associated kinase pathway in the migration of dental pulp cells.
    Experimental cell research, 2010, Apr-01, Volume: 316, Issue:6

    Topics: Actins; Adult; Amides; Cell Movement; Cells, Cultured; Dental Pulp; Enzyme Activation; Enzyme Inhibitors; Humans; Lysophospholipids; Pyridines; rac1 GTP-Binding Protein; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Young Adult

2010
Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival.
    The Journal of biological chemistry, 2010, Aug-13, Volume: 285, Issue:33

    Topics: Amides; Animals; Animals, Newborn; Calcium; Cell Line; Cell Survival; Cells, Cultured; Cytosol; Enzyme Inhibitors; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Models, Biological; Osteoclasts; Pertussis Toxin; Pyridines; Rabbits; Rats; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction

2010
Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study.
    Urologia internationalis, 2011, Volume: 86, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Bacterial Proteins; Bacterial Toxins; Calcium; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Movement; Fura-2; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Lysophospholipids; Mutation; Pertussis Toxin; Phalloidine; Protein Kinase Inhibitors; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Type C Phospholipases

2011
The effect of lysophosphatidic acid and Rho-associated kinase patterning on adhesion of dental pulp cells.
    International endodontic journal, 2011, Volume: 44, Issue:1

    Topics: Adult; Amides; Cell Movement; Cells, Cultured; Dental Pulp; Focal Adhesion Kinase 1; Focal Adhesions; Humans; Lysophospholipids; Paxillin; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Tyrosine; Young Adult

2011
LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells.
    Journal of cellular physiology, 2011, Volume: 226, Issue:11

    Topics: Amides; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Female; Heterocyclic Compounds, 4 or More Rings; Lysophospholipids; Mice; Myosin Light Chains; Pertussis Toxin; Phosphorylation; Pyridines; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction

2011
RhoA-ROCK-Myosin pathway regulates morphological plasticity of cultured olfactory ensheathing cells.
    Experimental cell research, 2011, Dec-10, Volume: 317, Issue:20

    Topics: Actins; Amides; Animals; Biosensing Techniques; Cells, Cultured; Lysophospholipids; Myosins; Neuroglia; Neuronal Plasticity; Olfactory Pathways; Pseudopodia; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Serum; Signal Transduction

2011
Wnt-signaling mediates the anti-adipogenic action of lysophosphatidic acid through cross talking with the Rho/Rho associated kinase (ROCK) pathway.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2011, Volume: 89, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Adipogenesis; Amides; Animals; beta Catenin; Gene Expression Regulation; Lysophospholipids; Mice; PPAR gamma; Pyridines; Receptor Cross-Talk; rho-Associated Kinases; RNA, Messenger; Time Factors; Transcriptional Activation; Wnt Proteins; Wnt Signaling Pathway

2011
The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion.
    Oncogene, 2012, Sep-27, Volume: 31, Issue:39

    Topics: Amides; Cell Line, Tumor; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Neoplasm Invasiveness; NF-kappa B; Nitriles; Ovarian Neoplasms; Peptide Hydrolases; Pyridines; rho-Associated Kinases; Sulfones; Urokinase-Type Plasminogen Activator

2012
Uniaxial mechanical tension promoted osteogenic differentiation of rat tendon-derived stem cells (rTDSCs) via the Wnt5a-RhoA pathway.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:10

    Topics: Alkaline Phosphatase; Amides; Animals; Biomechanical Phenomena; Cell Differentiation; Cell Lineage; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Core Binding Factor Alpha 1 Subunit; Lysophospholipids; Male; Ossification, Heterotopic; Osteogenesis; Pyridines; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; RNA, Messenger; Staining and Labeling; Stem Cells; Stress, Mechanical; Tendinopathy; Tendons; Wnt Proteins; Wnt Signaling Pathway; Wnt-5a Protein

2012
Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves.
    Developmental biology, 2013, Feb-15, Volume: 374, Issue:2

    Topics: Amides; Animals; Avian Proteins; Blotting, Western; Chick Embryo; Cytoskeleton; Extracellular Matrix; Extracellular Matrix Proteins; Gene Expression Profiling; Heart Valves; Lysophospholipids; Mechanotransduction, Cellular; Microscopy, Atomic Force; Microscopy, Confocal; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Stress, Mechanical; Tenascin; Time Factors; Tissue Culture Techniques

2013
Role of Rho kinase in lysophosphatidic acid-induced altering of blood-brain barrier permeability.
    International journal of molecular medicine, 2014, Volume: 33, Issue:3

    Topics: Amides; Animals; Blood-Brain Barrier; Corpus Striatum; Endothelial Cells; Lysophospholipids; Matrix Metalloproteinase 9; Permeability; Pyridines; Rats; rho-Associated Kinases; Signal Transduction; Urokinase-Type Plasminogen Activator

2014
RhoA and Rac1 play independent roles in lysophosphatidic acid-induced ovarian cancer chemotaxis.
    Integrative biology : quantitative biosciences from nano to macro, 2014, Volume: 6, Issue:3

    Topics: ADP Ribose Transferases; Amides; Aminoquinolines; Botulinum Toxins; Cell Line, Tumor; Chemotaxis; Enzyme Inhibitors; Female; Guanine Nucleotide Exchange Factors; Humans; Lysophospholipids; Microfluidic Analytical Techniques; Ovarian Neoplasms; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; rho-Associated Kinases; rhoA GTP-Binding Protein

2014
Compaction, fusion, and functional activation of three-dimensional human mesenchymal stem cell aggregate.
    Tissue engineering. Part A, 2015, Volume: 21, Issue:9-10

    Topics: Actins; Amides; Caspase Inhibitors; Caspases; Cell Adhesion; Cell Aggregation; Cell Communication; Cell Culture Techniques; Cell Fusion; Cell Hypoxia; Cell Movement; Cell Shape; Cell Size; Cell Survival; Cytochalasin D; Humans; Lysophospholipids; Mesenchymal Stem Cells; Nocodazole; Pyridines; rho-Associated Kinases

2015
Interaction between mDia1 and ROCK in Rho-induced migration and adhesion of human dental pulp cells.
    International endodontic journal, 2017, Volume: 50, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Amides; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Dental Pulp; Formins; Humans; Lysophospholipids; Pyridines; rho-Associated Kinases; RNA, Small Interfering; Young Adult

2017
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
    Nature communications, 2016, Feb-08, Volume: 7

    Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles

2016
Regulation of Microglial Phagocytosis by RhoA/ROCK-Inhibiting Drugs.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Biological Assay; Cell Line; Down-Regulation; Humans; Ibuprofen; Lysophospholipids; Mice; Microglia; Nitric Oxide; Phagocytosis; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2017