y 27632 has been researched along with isoproterenol in 13 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (isoproterenol) | Trials (isoproterenol) | Recent Studies (post-2010) (isoproterenol) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 30,780 | 803 | 2,640 |
| Protein | Taxonomy | y 27632 (IC50) | isoproterenol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.246 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.333 | |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 1.77 | |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | 0.6667 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (69.23) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Ito, S; Ito, Y; Kume, H; Yamaki, K | 1 |
| Aihara, M; Dobashi, K; Iizuka, K; Mori, M; Nakazawa, T | 1 |
| Chu, L; Endoh, M; Norota, I | 1 |
| Honjo, H; Ito, S; Kamiya, K; Kodama, I; Kume, H; Oguma, T; Shimokata, K; Takeda, N | 1 |
| Hirakawa, M; Ito, Y; Karashima, Y; Kimura, C; Oike, M; Watanabe, M | 1 |
| Gambaryan, S; Roewer, N; Tas, PW | 1 |
| Akaike, A; Ito, R; Izumi, Y; Katsuki, H; Kume, T; Niidome, T; Sugimoto, H; Taguchi, R; Takada-Takatori, Y | 1 |
| Ramos, RF; Stamer, WD; Sumida, GM | 1 |
| Hasegawa, Y; Honjo, H; Kamiya, K; Kume, H; Makino, Y; Oguma, T; Shiraki, A; Sugishita, M | 1 |
| Rattan, S; Singh, J | 1 |
| Alexandre, EC; Alves Junior, MJ; Antunes, E; Báu, FR; Calmasini, FB; Leiria, LO; Mónica, FZ; Silva, FH | 1 |
| Chambers, JP; Hulls, CM; King, QM; Lentle, RG; Reynolds, GW | 1 |
13 other study(ies) available for y 27632 and isoproterenol
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle.
Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Amides; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Lysophosphatidylcholines; Male; Maleimides; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Adrenergic, beta; rho GTP-Binding Proteins; Spectrometry, Fluorescence; Theophylline; Trachea; Virulence Factors, Bordetella | 2001 |
Comparison of effects of Y-27632 and Isoproterenol on release of cytokines from human peripheral T cells.
Topics: Amides; Concanavalin A; Cytokines; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-5; Isoproterenol; Leukocytes, Mononuclear; Pyridines; T-Lymphocytes; Th1 Cells; Th2 Cells | 2003 |
Differential inhibition by the Rho kinase inhibitor Y-27632 of the increases in contractility and Ca2+ transients induced by endothelin-1 in rabbit ventricular myocytes.
Topics: Adrenergic beta-Agonists; Amides; Animals; Calcium; Cell Size; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Papillary Muscles; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases | 2005 |
Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle.
Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Bucladesine; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP Receptor Protein; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Fura-2; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Maleimides; Marine Toxins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Oxazoles; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Trachea | 2006 |
Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
Topics: Actins; Amides; Animals; Bucladesine; Carbazoles; Cattle; Cell Membrane; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Pyrroles; rho-Associated Kinases; Theophylline; Trachea | 2007 |
Volatile anesthetics affect the morphology of rat glioma C6 cells via RhoA, ERK, and Akt activation.
Topics: Adrenergic beta-Agonists; Amides; Anesthetics, Inhalation; Animals; Cell Line, Tumor; Cell Shape; Culture Media, Serum-Free; Enzyme Activation; Flavonoids; Glioma; Halothane; Isoflurane; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oncogene Protein v-akt; Pyridines; Rats; rhoA GTP-Binding Protein; Signal Transduction | 2007 |
Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes.
Topics: Adrenergic beta-Agonists; Amides; Animals; Astrocytes; Bucladesine; Carbazoles; Cell Shape; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Neuroprotective Agents; Pyridines; Pyrroles; Rats; Rats, Wistar; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Cyclic mechanical stress and trabecular meshwork cell contractility.
Topics: Actins; Amides; Blotting, Western; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Immunoblotting; Isoproterenol; L-Lactate Dehydrogenase; Microscopy, Fluorescence; Myosin Light Chains; Nifedipine; Phosphorylation; Pilocarpine; Pressure; Pyridines; rho-Associated Kinases; Stress, Mechanical; Trabecular Meshwork | 2009 |
Role of sphingosine-1-phosphate inβ-adrenoceptor desensitization via Ca(2+) sensitization in airway smooth muscle.
Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Calcium Signaling; Cells, Cultured; Guinea Pigs; Humans; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Pertussis Toxin; Pyridines; Receptors, Adrenergic, beta; rho-Associated Kinases; Sphingosine; Trachea | 2012 |
Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS.
Topics: Adrenergic beta-Agonists; Amides; Anal Canal; Bethanechol; Gene Expression Regulation, Enzymologic; Humans; Indoles; Isoproterenol; Maleimides; Muscarinic Agonists; Muscle Tonus; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Pyridines; rho-Associated Kinases; Tissue Engineering | 2012 |
Increased Rho-kinase-mediated prostate contractions associated with impairment of β-adrenergic-cAMP-signaling pathway by chronic nitric oxide deficiency.
Topics: Adenosine Triphosphate; Amides; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Prostate; Pyridines; Rats; rho-Associated Kinases; Signal Transduction | 2015 |
Pharmacological modulation of the spatiotemporal disposition of micromotions in the intact resting urinary bladder of the rabbit; their pattern is under both myogenic and autonomic control.
Topics: Adrenergic beta-Agonists; Amides; Animals; Carbachol; Carbenoxolone; Cholinergic Agonists; Isoproterenol; Muscle Contraction; Muscle Relaxants, Central; Pyridines; Rabbits; rho-Associated Kinases; Urinary Bladder | 2019 |