y 27632 has been researched along with indazoles in 6 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (indazoles) | Trials (indazoles) | Recent Studies (post-2010) (indazoles) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 5,609 | 550 | 3,265 |
| Protein | Taxonomy | y 27632 (IC50) | indazoles (IC50) |
|---|---|---|---|
| Chain A, Cell Division Protein Kinase 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, Cell Division Protein Kinase 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, CELL DIVISION PROTEIN KINASE 2 | Homo sapiens (human) | 185 | |
| Chain A, Cell Division Protein Kinase 2 | Homo sapiens (human) | 185 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adam, J; Bennett, J; Black, D; Boucharens, S; Brown, AR; Cook, A; de Man, J; Epemolu, O; Fletcher, D; Haunso, A; Huggett, M; Jones, P; Laats, S; Lyons, A; Mestres, J; Morphy, R; Rankovic, Z; Ray, P; Sherborne, B; Sherry, L; van Straten, N; Westwood, P; Wright, J; Zaman, GZ | 1 |
| Cheng, CY; Lee, WM; Lui, WY | 1 |
| Abraham, A; Adams, DR; Allcock, RW; Andrews, PD; Aspegren, A; Becroft, M; Frearson, JA; Gilmour, J; Houslay, MD; James, MJ; Jiang, Z; Kime, R; McRae, S; Milligan, G; Mountford, JC; Strehl, R | 1 |
| Chou, AH; Hu, SH; Wang, HL; Wang, SS; Weng, YH; Yeh, TH | 1 |
| Allain, AV; Kadowitz, PJ; Lasker, GF; Murthy, SN; Pankey, EA; Stasch, JP | 1 |
| Borchiellini, C; Fierro-Constain, L; Hall, C; Hill, AL; Quintero, O; Renard, E; Schenkelaars, Q | 1 |
6 other study(ies) available for y 27632 and indazoles
| Article | Year |
|---|---|
Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
Topics: Amines; Animals; Binding Sites; Computer Simulation; Crystallography, X-Ray; Drug Evaluation, Preclinical; Isoquinolines; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; rho-Associated Kinases; Structure-Activity Relationship | 2011 |
Sertoli-germ cell adherens junction dynamics in the testis are regulated by RhoB GTPase via the ROCK/LIMK signaling pathway.
Topics: Adherens Junctions; Algorithms; Amides; Animals; Brain; Cells, Cultured; Coculture Techniques; Germ Cells; GTP Phosphohydrolases; Hydrazines; Immunoblotting; Immunohistochemistry; Indazoles; Intracellular Signaling Peptides and Proteins; Kidney; Male; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoB GTP-Binding Protein; RNA, Messenger; Seminiferous Epithelium; Sertoli Cells; Signal Transduction; Testis | 2003 |
High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules.
Topics: Amides; Cell Culture Techniques; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Embryonic Stem Cells; Heterocyclic Compounds; Humans; Indazoles; Molecular Structure; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Time Factors | 2010 |
H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Ataxin-3; Ataxin-7; Brain; Dose-Response Relationship, Drug; Gene Expression; Humans; Indazoles; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Niacinamide; Nuclear Proteins; Peptides; Proteasome Endopeptidase Complex; Pyridines; rho-Associated Kinases; Transcription Factors | 2013 |
The selective Rho-kinase inhibitor azaindole-1 has long-lasting erectile activity in the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Area Under Curve; Atropine; Blood Pressure; Diamines; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Male; Muscarinic Antagonists; Nitric Oxide; Oxadiazoles; Penile Erection; Penis; Peripheral Nerve Injuries; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; rho-Associated Kinases; Signal Transduction; Time Factors | 2013 |
ROCK inhibition abolishes the establishment of the aquiferous system in Ephydatia muelleri (Porifera, Demospongiae).
Topics: Amides; Animals; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Indazoles; Morphogenesis; Niacinamide; Phylogeny; Porifera; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; Species Specificity | 2016 |