Page last updated: 2024-09-03

y 27632 and guanosine 5'-o-(3-thiotriphosphate)

y 27632 has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 20 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(guanosine 5'-o-(3-thiotriphosphate))
Trials
(guanosine 5'-o-(3-thiotriphosphate))
Recent Studies (post-2010) (guanosine 5'-o-(3-thiotriphosphate))
1,92438915,5428368

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (25.00)18.2507
2000's14 (70.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fu, X; Gong, MC; Jia, T; Somlyo, AP; Somlyo, AV1
Ito, M; Nakano, T; Narumiya, S; Nishikawa, M; Sasaki, Y; Shiku, H; Suzuki, Y; Wada, H; Yamamoto, M1
Dobashi, K; Harada, T; Horie, T; Iizuka, K; Mori, M; Nakazawa, T; Yoshii, A1
Brown, JH; Kaplan, DD; Majumdar, M; Seasholtz, TM1
Dobashi, K; Iizuka, K; Ishizuka, T; Mori, M; Nakazawa, T; Samizo, K; Tsukagoshi, H; Yoshii, A1
Brautigan, DL; Eto, M; Kitazawa, T; Woodsome, TP1
Fujimura, A; Harada, K; Kawaguchi, A; Ohmori, M; Sugimoto, K; Tsuruoka, S1
Amano, M; Fukata, Y; Kaibuchi, K; Shimokawa, H1
Akahane, S; Anabuki, J; Hayakawa, K; Hori, M; Karaki, H; Ozaki, H1
Gong, MC; Gorenne, I; Jia, T; Nakamoto, RK; Read, P; Somlyo, AP; Somlyo, AV1
Brkic-Koric, D; Pfitzer, G; Sonntag-Bensch, D1
Bodie, SL; Ford, I; Greaves, M; Nixon, GF1
Hatano, Y; Ogawa, K; Tokinaga, Y; Yu, J1
Arner, A; Bonnevier, J1
Bi, D; Hirano, K; Kanaide, H; Niiro, N; Nishimura, J1
Brozovich, FV; Cochard, A; El-Touhky, A; Given, AM1
Kanaide, H; Naito, S; Nishimura, J; Seki, N; Takahashi, R; Tomoda, T; Yunoki, T1
Erb, L; Liao, Z; Seye, CI; Weisman, GA1
Prieto, D; Simonsen, U; Stankevicius, E; Villalba, N1
Bayguinov, O; Dwyer, L; Kim, H; Koh, SD; Marklew, A; Sanders, KM1

Other Studies

20 other study(ies) available for y 27632 and guanosine 5'-o-(3-thiotriphosphate)

ArticleYear
The effects of the Rho-kinase inhibitor Y-27632 on arachidonic acid-, GTPgammaS-, and phorbol ester-induced Ca2+-sensitization of smooth muscle.
    FEBS letters, 1998, Nov-27, Volume: 440, Issue:1-2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Arachidonic Acid; Calcium; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Octoxynol; Permeability; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; Rabbits; rho-Associated Kinases; Type C Phospholipases

1998
Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase.
    Blood, 1999, May-15, Volume: 93, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amides; Blood Platelets; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Myosin-Light-Chain Phosphatase; Myosins; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein

1999
Relaxation of contracted rabbit tracheal and human bronchial smooth muscle by Y-27632 through inhibition of Ca2+ sensitization.
    American journal of respiratory cell and molecular biology, 1999, Volume: 20, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Amides; Animals; Bronchi; Calcium; Carbachol; Cholinergic Agents; Detergents; Dose-Response Relationship, Drug; Endothelin-1; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Intracellular Signaling Peptides and Proteins; Marine Toxins; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Octoxynol; Oxazoles; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Signal Transduction; Trachea; Type C Phospholipases

1999
Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration.
    Circulation research, 1999, May-28, Volume: 84, Issue:10

    Topics: Adenosine Diphosphate Ribose; Amides; Animals; Aorta; Cell Movement; Cells, Cultured; DNA; Enzyme Inhibitors; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hemostatics; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Sulfur Radioisotopes; Thrombin; Tritium

1999
A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea.
    British journal of pharmacology, 1999, Volume: 128, Issue:4

    Topics: Amides; Animals; Calcium; Enzyme Inhibitors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Myosin-Light-Chain Phosphatase; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Trachea

1999
Agonists trigger G protein-mediated activation of the CPI-17 inhibitor phosphoprotein of myosin light chain phosphatase to enhance vascular smooth muscle contractility.
    The Journal of biological chemistry, 2000, Apr-07, Volume: 275, Issue:14

    Topics: Amides; Animals; Cell Membrane Permeability; Enzyme Inhibitors; Femoral Artery; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Histamine; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phenylephrine; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rabbits; rho-Associated Kinases; Type C Phospholipases

2000
The effect of a Rho kinase inhibitor Y-27632 on superoxide production, aggregation and adhesion in human polymorphonuclear leukocytes.
    European journal of pharmacology, 2000, Sep-08, Volume: 403, Issue:3

    Topics: Adult; Amides; Calcimycin; Calcium; Cell Adhesion; Cell Aggregation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Superoxides; Tetradecanoylphorbol Acetate; Thapsigargin

2000
Purification and in vitro activity of Rho-associated kinase.
    Methods in enzymology, 2000, Volume: 325

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Baculoviridae; Catalytic Domain; Cattle; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Staurosporine

2000
Muscarinic stimulation does not induce rhoA/ROCK-mediated Ca2+ sensitization of the contractile element in chicken gizzard smooth muscle.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 441, Issue:2-3

    Topics: Amides; Animals; Calcium; Carbachol; Chickens; Enzyme Inhibitors; Female; Gene Expression; Gizzard, Avian; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium; Protein Serine-Threonine Kinases; Pyridines; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Verapamil

2000
Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:1

    Topics: Amides; Animals; Calcium; Cell Membrane; Enzyme Inhibitors; Escin; Guanine Nucleotide Dissociation Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Ileum; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Portal Vein; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Rabbits; Recombinant Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Urinary Bladder; Vasoconstrictor Agents; Yeasts

2001
Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase.
    The Journal of physiology, 2001, Jun-15, Volume: 533, Issue:Pt 3

    Topics: Actin Cytoskeleton; Adenosine Triphosphate; Amides; Animals; Calcium; Carbachol; Drug Synergism; Enzyme Inhibitors; Female; Gastrointestinal Motility; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Staurosporine; Sulfhydryl Compounds; Sulfur

2001
Thrombin-induced activation of RhoA in platelet shape change.
    Biochemical and biophysical research communications, 2001, Sep-14, Volume: 287, Issue:1

    Topics: Amides; Blood Platelets; Calcium; Cell Membrane Permeability; Cell Size; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Myosin Light Chains; Myosins; Phosphorylation; Pyridines; rhoA GTP-Binding Protein; Thrombin

2001
Sevoflurane inhibits guanosine 5'-[gamma-thio]triphosphate-stimulated, Rho/Rho-kinase-mediated contraction of isolated rat aortic smooth muscle.
    Anesthesiology, 2003, Volume: 99, Issue:3

    Topics: Amides; Anesthetics, Inhalation; Animals; Aorta, Thoracic; Cell Membrane; Cytosol; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Male; Methyl Ethers; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases; Sevoflurane; Signal Transduction

2003
Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle.
    The Journal of biological chemistry, 2004, 07-09, Volume: 279, Issue:28

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amides; Animals; Bacterial Toxins; Blood Vessels; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Escin; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intestine, Small; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Permeability; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases

2004
Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility.
    Circulation research, 2005, Apr-29, Volume: 96, Issue:8

    Topics: Amides; Animals; Calcium; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphorylation; Protein Kinase C; Pyridines; rhoA GTP-Binding Protein; RNA Interference; Swine; Vasoconstriction

2005
PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle.
    FEBS letters, 2005, Aug-15, Volume: 579, Issue:20

    Topics: Amides; Animals; Calcium; Chickens; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Maleimides; Muscle, Smooth; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Proteins; Pyridines; Threonine

2005
RhoA/Rho kinase-mediated Ca2+ sensitization in the contraction of human prostate.
    Neurourology and urodynamics, 2007, Volume: 26, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Blotting, Western; Calcium; Cells, Cultured; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Prostate; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Type C Phospholipases

2007
The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.
    Journal of cell science, 2007, May-01, Volume: 120, Issue:Pt 9

    Topics: Amides; Antibodies, Monoclonal; Cardiac Myosins; Cell Line, Tumor; Cell Movement; Cofilin 1; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gq-G11; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Integrin alphaV; Integrins; Mutation; Myosin Light Chains; Oligonucleotides, Antisense; Pertussis Toxin; Phosphorylation; Protein Binding; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Receptors, Vitronectin; rho GTP-Binding Proteins; Signal Transduction; Stress Fibers; Transfection; Uridine Triphosphate

2007
Rho kinase is involved in Ca2+ entry of rat penile small arteries.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Amides; Animals; Arteries; Bacterial Toxins; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Penis; Phenylephrine; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; rho-Associated Kinases; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents

2008
Contribution of Rho-kinase to membrane excitability of murine colonic smooth muscle.
    British journal of pharmacology, 2011, Volume: 163, Issue:3

    Topics: Amides; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Cell Membrane; Colon; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Membrane Potentials; Mice; Muscle Contraction; Muscle, Smooth; Patch-Clamp Techniques; Pyridines; rho-Associated Kinases

2011