y 27632 has been researched along with go 6976 in 12 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (go 6976) | Trials (go 6976) | Recent Studies (post-2010) (go 6976) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 504 | 1 | 133 |
| Protein | Taxonomy | y 27632 (IC50) | go 6976 (IC50) |
|---|---|---|---|
| Protein kinase C gamma type | Homo sapiens (human) | 0.002 | |
| Protein kinase C beta type | Homo sapiens (human) | 0.0041 | |
| Protein kinase C alpha type | Homo sapiens (human) | 0.0027 | |
| Protein kinase C delta type | Homo sapiens (human) | 0.446 | |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | 0.0445 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caivano, M; Cohen, P; Davies, SP; Reddy, H | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Brautigan, DL; Eto, M; Kitazawa, T; Mukai, H; Ono, Y; Yazawa, M | 1 |
| Gimona, M; Hahne, P; Hai, CM; Harrington, EO | 1 |
| Hirata Terra, J; Millward, TA; Montaño, I; Schilb, A | 1 |
| Procino, G; Svelto, M; Tamma, G; Valenti, G | 1 |
| Ito, Y; Mitate, A; Nakayama, K; Nozawa, K; Obara, K; Watanabe, M | 1 |
| Hori, M; Kishi, H; Kobayashi, S; Mori, D; Murata, T; Ohama, T; Ozaki, H | 1 |
| Kim, BJ; Kim, JN | 1 |
12 other study(ies) available for y 27632 and go 6976
| Article | Year |
|---|---|
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides | 2000 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms.
Topics: Amides; Amino Acid Sequence; Animals; Aorta; Carbazoles; Chromatography; Chromatography, Affinity; Chromatography, Ion Exchange; Durapatite; Enzyme Activation; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indoles; Isoenzymes; Kinetics; Maleimides; Molecular Sequence Data; Muscle Contraction; Muscle Proteins; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Myelin Basic Protein; Myosin-Light-Chain Phosphatase; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Pyridines; Recombinant Proteins; Substrate Specificity; Swine; Vasoconstriction | 2001 |
Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in a7r5 smooth muscle cells.
Topics: Acetophenones; Actinin; Actins; Amides; Animals; Benzopyrans; Carbazoles; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Green Fluorescent Proteins; Indoles; Isoenzymes; Luminescent Proteins; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Transport; Pyridines; Rats; Recombinant Fusion Proteins; Transfection; Vinculin | 2002 |
Development of a microplate bioassay for monocyte chemoattractant protein-1 based on activation of p44/42 mitogen-activated protein kinase.
Topics: Amides; Animals; Antibodies, Monoclonal; Biological Assay; Carbazoles; Cell Line; Chemokine CCL2; Chromones; Cricetinae; DNA, Complementary; Enzyme Inhibitors; Indoles; Microchemistry; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Phosphorylation; Promoter Regions, Genetic; Pyridines; Receptors, CCR2; Receptors, Chemokine; Transfection | 2004 |
Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells.
Topics: Actins; Amides; Animals; Calcium; Carbazoles; Cell Membrane; Cell Size; Cell Surface Extensions; Cells, Cultured; Enzyme Activation; Hypotonic Solutions; Indoles; Kidney Tubules, Collecting; Microfilament Proteins; Osmotic Pressure; Phosphorylation; Protein Binding; Protein Kinase C-alpha; Pyridines; Rabbits; Stress Fibers | 2007 |
Interactive role of protein phosphatase 2A and protein kinase Calpha in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery.
Topics: Amides; Animals; Basilar Artery; Carbazoles; Cerebral Arteries; Dogs; Enzyme Activation; Female; In Vitro Techniques; Male; Myosin Light Chains; Okadaic Acid; Phosphorylation; Pressoreceptors; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Phosphatase 2; Pyridines; rho-Associated Kinases; Signal Transduction; Time Factors; Vasoconstriction | 2010 |
Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle.
Topics: Amides; Animals; Calcium; Carbachol; Carbazoles; Cholinergic Agonists; Guanosine Triphosphate; Intestines; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Phosphoproteins; Phosphorylation; Potassium; Protein Kinase C; Protein Phosphatase 1; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2011 |
The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine.
Topics: Acetophenones; Amides; Animals; Benzopyrans; Boron Compounds; Calcium; Carbazoles; Gastrointestinal Motility; Ghrelin; Inositol 1,4,5-Trisphosphate Receptors; Interstitial Cells of Cajal; Intestine, Small; Macrocyclic Compounds; Membrane Potentials; Mice; Mice, Inbred ICR; Motilin; Oligopeptides; Oxazoles; Protein Kinase C; Pyridines; Receptors, Ghrelin; rho-Associated Kinases; Signal Transduction; Staurosporine; Thapsigargin | 2019 |