y 27632 has been researched along with ggti 286 in 6 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (ggti 286) | Trials (ggti 286) | Recent Studies (post-2010) (ggti 286) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 25 | 0 | 7 |
| Protein | Taxonomy | y 27632 (IC50) | ggti 286 (IC50) |
|---|---|---|---|
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | 0.6748 | |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | 0.017 | |
| Geranylgeranyl transferase type-1 subunit beta | Homo sapiens (human) | 1.0037 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bertoglio, J; Blaie, S; Bolla, M; Boquet, P; Créminon, C; Degraeve, F; Habib, A; Lévy-Toledano, S; Quéré, I | 1 |
| Kamiyama, M; Kondo, K; Kurata, H; Tajima, N; Taniguchi, K; Utsunomiya, K; Yokota, T | 1 |
| Ito, S; Ito, Y; Kondo, M; Kume, H; Shimokata, K; Takeda, N | 1 |
| Chen, JW; Chen, YH; Chen, YL; Hsieh, LY; Ku, HH; Lin, CY; Lin, FY; Lin, SJ; Wang, SH; Wang, YC | 1 |
| Hodgkinson, CP; Ye, S | 1 |
| Asano, T; Hasegawa, Y; Kondo, M; Kume, H; Sashio, T; Shimokata, K; Takeda, N; Tsuji, S | 1 |
6 other study(ies) available for y 27632 and ggti 286
| Article | Year |
|---|---|
Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins.
Topics: Amides; Aorta; Apoptosis; Bacterial Proteins; Bacterial Toxins; Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dactinomycin; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoprostenol; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inhibitory Concentration 50; Interleukin-1; Isoenzymes; Leucine; Lovastatin; Membrane Proteins; Mevalonic Acid; Muscle, Smooth; Nucleic Acid Synthesis Inhibitors; Prostaglandin-Endoperoxide Synthases; Protein Prenylation; Pyridines; rho GTP-Binding Proteins; Time Factors | 2001 |
Contribution of Rho A and Rho kinase to platelet-derived growth factor-BB-induced proliferation of vascular smooth muscle cells.
Topics: Amides; Animals; Arteriosclerosis; Cell Division; Cells, Cultured; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Leucine; Methionine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein | 2003 |
Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin.
Topics: ADP Ribose Transferases; Alkyl and Aryl Transferases; Amides; Anti-Asthmatic Agents; Botulinum Toxins; Bronchi; cdc42 GTP-Binding Protein; Cell Membrane; Cell Proliferation; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Intracellular Signaling Peptides and Proteins; Leucine; Mitogens; Muscle, Smooth; Phosphorylation; Protein Prenylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyridines; rac1 GTP-Binding Protein; rho-Associated Kinases; rhoA GTP-Binding Protein; Simvastatin; Terpenes | 2006 |
Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity.
Topics: Amides; Anthracenes; Aorta; Blotting, Western; Boron Compounds; cdc42 GTP-Binding Protein; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Endothelial Cells; Enzyme Activation; Flavonoids; Humans; Imidazoles; Leucine; Mitogen-Activated Protein Kinases; Phosphorylation; Pravastatin; Protein Transport; Pyridines; rac1 GTP-Binding Protein; Thrombomodulin; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression.
Topics: Acyl Coenzyme A; Amides; Anticholesteremic Agents; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-6; Kidney; Leucine; Lipopolysaccharides; NF-kappa B; Pravastatin; Pyridines; Signal Transduction; Simvastatin; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2008 |
Possible Involvement of Sphingosine-1-Phosphate/G(i)/RhoA pathways in adherence of eosinophils to pulmonary endothelium.
Topics: ADP Ribose Transferases; Amides; Botulinum Toxins; Cell Adhesion; Cell Line; Endothelium, Vascular; Eosinophils; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Leucine; Lung; Lysophospholipids; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Sphingosine; Vascular Cell Adhesion Molecule-1 | 2012 |