y 27632 has been researched along with geldanamycin in 4 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (geldanamycin) | Trials (geldanamycin) | Recent Studies (post-2010) (geldanamycin) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 96 | 0 | 59 |
| 1,924 | 3 | 891 | 1,167 | 1 | 329 |
| Protein | Taxonomy | y 27632 (IC50) | geldanamycin (IC50) |
|---|---|---|---|
| Lysine-specific demethylase 6B | Homo sapiens (human) | 0.4 | |
| Lysine-specific demethylase 4B | Homo sapiens (human) | 0.7 | |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | 3 | |
| ATP-dependent molecular chaperone HSP82 | Saccharomyces cerevisiae S288C | 3.9667 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.014 | |
| Heat shock protein HSP 90-alpha | Homo sapiens (human) | 0.0917 | |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | 0.098 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.014 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.014 | |
| Breakpoint cluster region protein | Homo sapiens (human) | 3 | |
| Heat shock protein HSP 90 | Oryctolagus cuniculus (rabbit) | 1.141 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.074 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.014 | |
| Cytochrome P450 3A7 | Homo sapiens (human) | 0.014 | |
| Lysine-specific demethylase 5A | Homo sapiens (human) | 0.13 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.074 | |
| Endoplasmin | Canis lupus familiaris (dog) | 0.01 | |
| Heat shock protein 75 kDa, mitochondrial | Homo sapiens (human) | 0.661 | |
| Putative heat shock protein HSP 90-alpha A4 | Homo sapiens (human) | 0.14 | |
| Lysine-specific demethylase 4C | Homo sapiens (human) | 0.7 | |
| Cytochrome P450 3A43 | Homo sapiens (human) | 0.014 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Houle, F; Huot, J; Le Boeuf, F | 1 |
| Agrawal, N; Apostol, BL; Bodai, L; Chang, LW; Chiang, AS; Marsh, JL; Pallos, J; Slepko, N; Thompson, LM | 1 |
4 other study(ies) available for y 27632 and geldanamycin
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities.
Topics: Amides; Benzoquinones; CD18 Antigens; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; DNA, Complementary; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Gene Transfer Techniques; Genes, Dominant; Green Fluorescent Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Luminescent Proteins; Mutation; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Pyridines; Quinones; rhoA GTP-Binding Protein; src-Family Kinases; Time Factors; Tyrosine; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2; Vinculin | 2004 |
Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.
Topics: Amides; Animals; Benzoquinones; Disease Models, Animal; Drosophila; Drug Therapy, Combination; Female; Huntington Disease; Hydroxamic Acids; Lactams, Macrocyclic; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Pyridines; Quinones; Vorinostat | 2005 |