y 27632 has been researched along with ex 527 in 2 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (ex 527) | Trials (ex 527) | Recent Studies (post-2010) (ex 527) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 225 | 2 | 209 |
| Protein | Taxonomy | y 27632 (IC50) | ex 527 (IC50) |
|---|---|---|---|
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | 2.725 | |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | 0.3666 | |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Homo sapiens (human) | 6.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Fu, C; Hao, S; Jin, W; Li, S; Liu, Z; Lu, H; Wang, L; Xu, X; Zhou, J | 1 |
2 other study(ies) available for y 27632 and ex 527
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability.
Topics: Acute Lung Injury; Administration, Inhalation; Amides; Animals; Carbazoles; Cell Membrane Permeability; Endothelial Cells; Enzyme Activators; Enzyme Inhibitors; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Lipopolysaccharides; Lung; Male; Mice, Inbred BALB C; Pyridines; Signal Transduction; Sirtuin 1; Tight Junction Proteins; Tight Junctions | 2019 |