Page last updated: 2024-09-03

y 27632 and eplerenone

y 27632 has been researched along with eplerenone in 2 studies

Compound Research Comparison

Studies (y 27632)	Trials (y 27632)	Recent Studies (post-2010) (y 27632)	Studies (eplerenone)	Trials (eplerenone)	Recent Studies (post-2010) (eplerenone)
1,924	3	891	1,036	172	577

Protein Interaction Comparison

Protein	Taxonomy	y 27632 (IC50)	eplerenone (IC50)
Mineralocorticoid receptor	Homo sapiens (human)		0.668
Mineralocorticoid receptor	Rattus norvegicus (Norway rat)		0.0398

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Diah, S; Gang, L; Hamid, MR; Hitomi, H; Kimura, S; Nagai, Y; Nishiyama, A; Tamiya, T; Zhang, GX; Zhang, W	1
Chen, D; Han, H; Huang, Y; Li, W; Li, Z; Ma, C; Peng, Y; Wei, J; Wu, W; Zhan, F	1

Other Studies

2 other study(ies) available for y 27632 and eplerenone

Article	Year
Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells. Experimental cell research, 2008, Dec-10, Volume: 314, Issue:20 Topics: Aldosterone; Amides; Animals; Cell Transdifferentiation; Collagen; Eplerenone; Gene Expression Regulation; Hypertrophy; Mesangial Cells; Mineralocorticoid Receptor Antagonists; Muscle Development; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; rho-Associated Kinases; Signal Transduction; Spironolactone	2008
Rho kinase pathway is likely responsible for the profibrotic actions of aldosterone in renal epithelial cells via inducing epithelial-mesenchymal transition and extracellular matrix excretion. Cell biology international, 2013, Volume: 37, Issue:7 Topics: Actins; Aldosterone; Amides; Cadherins; Cell Line; Collagen Type I; Collagen Type III; Epithelial Cells; Epithelial-Mesenchymal Transition; Eplerenone; Extracellular Matrix; Gene Expression Regulation; Humans; Kidney; Mineralocorticoid Receptor Antagonists; Protein Kinase Inhibitors; Pyridines; Receptors, Mineralocorticoid; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Spironolactone	2013

Article

Year

Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells.

Experimental cell research, 2008, Dec-10, Volume: 314, Issue:20

Topics: Aldosterone; Amides; Animals; Cell Transdifferentiation; Collagen; Eplerenone; Gene Expression Regulation; Hypertrophy; Mesangial Cells; Mineralocorticoid Receptor Antagonists; Muscle Development; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; rho-Associated Kinases; Signal Transduction; Spironolactone

2008

Rho kinase pathway is likely responsible for the profibrotic actions of aldosterone in renal epithelial cells via inducing epithelial-mesenchymal transition and extracellular matrix excretion.

Cell biology international, 2013, Volume: 37, Issue:7

Topics: Actins; Aldosterone; Amides; Cadherins; Cell Line; Collagen Type I; Collagen Type III; Epithelial Cells; Epithelial-Mesenchymal Transition; Eplerenone; Extracellular Matrix; Gene Expression Regulation; Humans; Kidney; Mineralocorticoid Receptor Antagonists; Protein Kinase Inhibitors; Pyridines; Receptors, Mineralocorticoid; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Spironolactone

2013