y 27632 and cyclic gmp

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Threonine

Topics: Action Potentials; Amides; Animals; Apamin; Boron Compounds; Calcium; Calcium Signaling; Carbachol; Charybdotoxin; Colforsin; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Fura-2; Guinea Pigs; Isotonic Contraction; Male; Mechanotransduction, Cellular; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridines; Transducers; Urinary Bladder

Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amides; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Penile Erection; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Serine-Threonine Kinases; Purinones; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Up-Regulation

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amides; Animals; Bacterial Toxins; Blood Vessels; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Escin; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Intestine, Small; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Permeability; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases

Topics: Adenoviridae; Amides; Animals; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Erectile Dysfunction; Gene Expression; Intracellular Signaling Peptides and Proteins; Male; Muscle Relaxants, Central; Myosin-Light-Chain Phosphatase; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Transfection

Topics: Amides; Animals; Blotting, Western; Celiac Artery; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Guanine Nucleotide Exchange Factors; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Intracellular Signaling Peptides and Proteins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Oxadiazoles; Phenylephrine; Potassium; Protein Serine-Threonine Kinases; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

Topics: Adenosine Triphosphate; Age Factors; Amides; Animals; Animals, Newborn; Carbachol; Cholinergic Agonists; Cholinergic Fibers; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Nifedipine; Pyridines; Receptors, Muscarinic; Scopolamine; Tetrodotoxin; Urinary Bladder; Vasodilator Agents

Topics: Amides; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Fetus; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Hypoxia; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Oxygen; Pregnancy; Protein Serine-Threonine Kinases; Pulmonary Artery; Pulmonary Circulation; Pyridines; rho-Associated Kinases; RNA, Messenger; Sheep; Vasodilation

Topics: Adrenergic beta-Agonists; Amides; Animals; Astrocytes; Bucladesine; Carbazoles; Cell Shape; Cells, Cultured; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Isoproterenol; Neuroprotective Agents; Pyridines; Pyrroles; Rats; Rats, Wistar; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Time Factors

Topics: Amides; Analysis of Variance; Animals; Blotting, Western; Cyclic GMP; Disease Models, Animal; Endotoxemia; Lipopolysaccharides; Male; Mesenteric Arteries; Nitric Oxide; Phosphorylation; Probability; Pyridines; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; Sensitivity and Specificity; Signal Transduction; Up-Regulation; Vasoconstriction; Vasodilation

Topics: Amides; Animals; Calcium Signaling; Carbachol; Cholinergic Agonists; Colon; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Jejunum; Marine Toxins; Membrane Proteins; Mice; Mice, Knockout; Muscle Relaxation; Muscle, Smooth; Mutation; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pyridines; rho-Associated Kinases; Time Factors

Topics: Amides; Animals; Apolipoproteins E; Atherosclerosis; Cyclic GMP; Endothelium, Vascular; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Nitric Oxide; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction

Topics: Actins; Amides; Animals; Animals, Newborn; Cardiomegaly; Cofilin 2; Cyclic GMP; Endothelin-1; Isoenzymes; Models, Biological; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Protein Transport; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Time Factors; Transcription Factors

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penis; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Species Specificity; Up-Regulation

Topics: Amides; Angiotensin II; Animals; Anticoagulants; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Heparin; Male; Mesenteric Arteries; Mice; Myosin Light Chains; Phosphorylation; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoconstriction

Topics: Adaptor Proteins, Signal Transducing; Amides; Animals; Calcium; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Muscle Contraction; Myocytes, Smooth Muscle; Myosin-Light-Chain Phosphatase; Phosphorylation; Pyridines; Rabbits; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; S-Nitrosoglutathione; Stomach

Topics: Adenosine Triphosphate; Amides; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Prostate; Pyridines; Rats; rho-Associated Kinases; Signal Transduction

Topics: Amides; Animals; Clitoris; Cyclic GMP; Estradiol; Female; Letrozole; Muscle, Smooth; Nitric Oxide; Nitriles; Ovariectomy; Pyridines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Testosterone; Triazoles