Page last updated: 2024-09-03

y 27632 and colforsin

y 27632 has been researched along with colforsin in 19 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(colforsin)
Trials
(colforsin)
Recent Studies (post-2010) (colforsin)
1,924389113,460461,298

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)colforsin (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)1.729
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.041
Adenylate cyclase type 1Homo sapiens (human)0.0955

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (57.89)29.6817
2010's7 (36.84)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Ito, S; Ito, Y; Kume, H; Yamaki, K1
Aktories, K; Klussmann, E; Maric, K; Rosenthal, W; Svelto, M; Tamma, G; Valenti, G1
Aktories, K; Barth, H; Boutillier, S; Brock, C; Feuerstein, TJ; Leemhuis, J; Meyer, DK; Nürnberg, B1
Brading, AF; Hashitani, H; Suzuki, H1
Chen, J; Gao, SY; Kobayashi, N; Li, CY; Matsuda, S; Miyawaki, K; Mominoki, K; Pan, L; Saito, K; Saito, S; Shigemoto, K; Terashita, T1
Goldshmidt, A; Hamill, CE; Hepler, JR; Lyuboslavsky, P; McKeon, RJ; Nicole, O; Sastre, A; Sorensen, SD; Traynelis, SF1
Awazu, M; Fujita, H; Hida, M; Ishikura, K1
Honjo, H; Ito, S; Kamiya, K; Kodama, I; Kume, H; Oguma, T; Shimokata, K; Takeda, N1
Gao, SY; Kobayashi, N; Li, CY; Matsuda, S; Shimokawa, T; Terashita, T; Yaoita, E1
Hirakawa, M; Ito, Y; Karashima, Y; Kimura, C; Oike, M; Watanabe, M1
Grönberg, M; Janson, ET; Oberg, KE; Saras, J; Stridsberg, M1
Bogatcheva, NV; Bresnick, AR; Kolosova, I; Mirzapoiazova, T; Poirier, C; Verin, AD; Zemskova, MA1
Banks, P; Blanco Suarez, EM; Cockbill, LM; Hanley, JG; Murk, K1
Dwinell, MB; Hauser, AD; Roy, I; Williams, CL; Wilson, JM; Zimmerman, NP1
Garcia-Diaz, A; Henderson, CE; Johnson-Kerner, B; Kim, YA; Lamas, NJ; Roybon, L; Wichterle, H1
Bond, M; Duggirala, A; Kimura, TE; Newby, AC; Sala-Newby, GB; Smith, MC; White, S1
Aguilera-Castrejon, A; Castro-Manrreza, ME; Cortés-Medina, LV; Mayani, H; Montesinos, JJ; Pasantes-Morales, H; Ramos-Mandujano, G1
Fan, SH; Li, XW; Niu, Y; Shi, YW; Xiong, QF; Zhang, LH; Zhang, X1
Cao, H; Chen, Z; Chi, S; Guo, S; Hu, Q; Sun, T; Tao, H; Yang, J; Zhang, L; Zhu, H1

Other Studies

19 other study(ies) available for y 27632 and colforsin

ArticleYear
Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle.
    American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:3

    Topics: Adenylate Cyclase Toxin; Adrenergic beta-Agonists; Amides; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Lysophosphatidylcholines; Male; Maleimides; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Adrenergic, beta; rho GTP-Binding Proteins; Spectrometry, Fluorescence; Theophylline; Trachea; Virulence Factors, Bordetella

2001
Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:6

    Topics: Actins; Amides; Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Bacterial Toxins; Cell Line; Cell Membrane; Cell Polarity; Colforsin; Cyclic AMP; Cytochalasin D; Cytoskeleton; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Kidney Tubules, Collecting; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Rabbits; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein

2001
Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites.
    The Journal of biological chemistry, 2004, Jan-02, Volume: 279, Issue:1

    Topics: Amides; Androstadienes; Animals; Brain; Colforsin; Dendrites; Enzyme Inhibitors; Genes, Reporter; Glioma; Glutathione Transferase; Humans; Kinetics; Myosin-Light-Chain Kinase; Neuroblastoma; Phosphatidylinositol 3-Kinases; Pyridines; Rats; Recombinant Fusion Proteins; rho GTP-Binding Proteins; Rolipram; Transfection; Tumor Cells, Cultured; Wortmannin

2004
Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: Action Potentials; Amides; Animals; Apamin; Boron Compounds; Calcium; Calcium Signaling; Carbachol; Charybdotoxin; Colforsin; Cromakalim; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Fura-2; Guinea Pigs; Isotonic Contraction; Male; Mechanotransduction, Cellular; Microelectrodes; Muscle Contraction; Muscle, Smooth; Nifedipine; Pyridines; Transducers; Urinary Bladder

2004
Rho-ROCK signal pathway regulates microtubule-based process formation of cultured podocytes--inhibition of ROCK promoted process elongation.
    Nephron. Experimental nephrology, 2004, Volume: 97, Issue:2

    Topics: Acetylation; Actin Cytoskeleton; Actins; Acute-Phase Proteins; ADP Ribose Transferases; Amides; Animals; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Colforsin; Cytoskeleton; Focal Adhesions; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Mice; Microtubules; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Thiazoles; Thiazolidines; Tubulin

2004
Activation of protease-activated receptor-1 triggers astrogliosis after brain injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Apr-27, Volume: 25, Issue:17

    Topics: Amides; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Blotting, Northern; Blotting, Western; Brain Injuries; Bromodeoxyuridine; Butadienes; Cell Count; Cell Movement; Cell Proliferation; Cells, Cultured; Coculture Techniques; Colforsin; Cyclin D1; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Functional Laterality; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Male; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Microglia; Nitriles; Oligopeptides; Pyridines; Receptor, PAR-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thrombin; Time Factors

2005
Trapidil inhibits platelet-derived growth factor-induced migration via protein kinase A and RhoA/Rho-associated kinase in rat vascular smooth muscle cells.
    European journal of pharmacology, 2005, May-16, Volume: 515, Issue:1-3

    Topics: Amides; Animals; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzymes; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Isoquinolines; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Sulfonamides; Thymidine; Trapidil; Tritium

2005
Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:2

    Topics: Adrenergic beta-Agonists; Amides; Animals; Asthma; Bucladesine; Calcium; Calcium Channel Blockers; Colforsin; Cyclic AMP Receptor Protein; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Fura-2; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Maleimides; Marine Toxins; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Phosphatase; Oxazoles; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Trachea

2006
Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro.
    Cell and tissue research, 2007, Volume: 328, Issue:2

    Topics: Actins; Adherens Junctions; Amides; Animals; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein; Cell Adhesion Molecules; Cell Communication; Cell Line; Colforsin; Extracellular Space; Kidney Glomerulus; Mice; Podocytes; Pyridines; rac1 GTP-Binding Protein; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Thiazolidines

2007
Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Actins; Amides; Animals; Bucladesine; Carbazoles; Cattle; Cell Membrane; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Pyrroles; rho-Associated Kinases; Theophylline; Trachea

2007
Somatostatin induces rapid contraction of neuroendocrine cells.
    FEBS letters, 2007, May-15, Volume: 581, Issue:10

    Topics: Actin Cytoskeleton; Amides; Cell Line, Tumor; Cell Shape; Cell Survival; Chromogranin A; Colforsin; Humans; Lysophospholipids; Neurosecretion; Neurosecretory Systems; Pyridines; Secretory Vesicles; Somatostatin; Time Factors

2007
The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier?
    Journal of cellular physiology, 2011, Volume: 226, Issue:12

    Topics: Amides; Calcium; Capillary Permeability; Cells, Cultured; Colforsin; Cyclic AMP; Dextrans; Electric Impedance; Endothelial Cells; Endotoxins; Fluorescein-5-isothiocyanate; Humans; Lung; Microvessels; Myosin Light Chains; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Transport; Pyridines; rho-Associated Kinases; RNA Interference; Signal Transduction; Time Factors; Transfection

2011
The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology.
    Journal of cell science, 2013, Sep-01, Volume: 126, Issue:Pt 17

    Topics: Actin-Related Protein 2-3 Complex; Amides; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Colforsin; Enzyme Inhibitors; Fibroblasts; HEK293 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Myosin Type II; Nuclear Proteins; Pyridines; Rats; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Thiazoles; Thiones; Uracil; Vasodilator Agents; Wiskott-Aldrich Syndrome Protein, Neuronal

2013
Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells.
    Molecular carcinogenesis, 2015, Volume: 54, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Amides; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Deoxycytidine; Enzyme Inhibitors; Gemcitabine; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Pyridines; Quinolones; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; rhoC GTP-Binding Protein; Vasodilator Agents

2015
Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Amides; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Ciliary Neurotrophic Factor; Colforsin; Cyclic AMP; Embryonic Stem Cells; Gene Expression; Glial Cell Line-Derived Neurotrophic Factor; Humans; Induced Pluripotent Stem Cells; Motor Neurons; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases

2014
The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP.
    Journal of molecular and cellular cardiology, 2016, Volume: 90

    Topics: Amides; Animals; Apoptosis Regulatory Proteins; Bridged Bicyclo Compounds, Heterocyclic; Bucladesine; Cell Proliferation; Colforsin; Connective Tissue Growth Factor; Cyclic AMP; Cysteine-Rich Protein 61; Epoprostenol; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth; Myocytes, Smooth Muscle; Primary Cell Culture; Proto-Oncogene Proteins c-myc; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Thiazolidines; Transcriptional Coactivator with PDZ-Binding Motif Proteins; Transforming Growth Factor beta2; YAP-Signaling Proteins

2016
Improved Proliferative Capacity of NP-Like Cells Derived from Human Mesenchymal Stromal Cells and Neuronal Transdifferentiation by Small Molecules.
    Neurochemical research, 2017, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Amides; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Colforsin; Drug Combinations; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mesenchymal Stem Cells; Neural Stem Cells; Neurons; Pyridines; Young Adult

2017
GLP-1 attenuates Ang II-induced proliferation and migration in rat aorta smooth muscle cells
    Die Pharmazie, 2018, 12-01, Volume: 73, Issue:12

    Topics: Amides; Angiotensin II; Animals; Aorta; Cell Movement; Cell Proliferation; Cells, Cultured; Colforsin; Glucagon-Like Peptide 1; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2018
Small molecular compounds efficiently convert human fibroblasts directly into neurons.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Amides; Anthracenes; Cell Differentiation; Cells, Cultured; Cellular Reprogramming; Cellular Reprogramming Techniques; Colforsin; Culture Media, Conditioned; Fibroblasts; Foreskin; Humans; Indoles; Male; Maleimides; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Pyrazoles; Pyridines; Pyrimidines; Transcription Factors

2020