Page last updated: 2024-09-03

y 27632 and colchicine

y 27632 has been researched along with colchicine in 8 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(colchicine)
Trials
(colchicine)
Recent Studies (post-2010) (colchicine)
1,924389115,4724042,974

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)colchicine (IC50)
Tubulin alpha-1A chainSus scrofa (pig)3.7639
Tubulin beta chainSus scrofa (pig)3.8663
Tubulin beta-4A chainHomo sapiens (human)2.4334
Tubulin beta chainHomo sapiens (human)2.7244
Tubulin alpha-3C chainHomo sapiens (human)2.4334
Serine/threonine-protein kinase pim-1Homo sapiens (human)4.3
Tubulin alpha-1B chainHomo sapiens (human)2.4334
Tubulin alpha-4A chainHomo sapiens (human)2.4334
Tubulin beta-4B chainHomo sapiens (human)2.4334
Vesicular acetylcholine transporterTetronarce californica (Pacific electric ray)2.62
Tubulin beta-3 chainHomo sapiens (human)2.4334
Tubulin beta-2A chainHomo sapiens (human)2.4334
Tubulin beta-8 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainBos taurus (cattle)2.8255
Tubulin alpha-3E chainHomo sapiens (human)2.4334
Tubulin alpha-1A chainHomo sapiens (human)2.4334
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0611
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.1553
Tubulin alpha-1C chainHomo sapiens (human)2.4334
Tubulin beta-6 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainHomo sapiens (human)2.4334
Tubulin beta-1 chainHomo sapiens (human)2.4334

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, N; Li, L; Rhoades, RA; Swartz, DR; Wang, Z; Yancey, KW; Zhang, D1
Eggli, P; Keller, H; Zadeh, AD1
Niggli, V1
Abe, K; Misawa, M1
Giehl, K; Goppelt-Struebe, M; Graness, A; Iwanciw, D; Ott, C1
Hordichok, AJ; Steyger, PS1
Badger, GJ; Barnes, WD; Bouffard, NA; Fox, JR; Howe, AK; Iatridis, JC; Langevin, HM; Palmer, BM; Wu, J1
Dulin, N; Kach, J; Kregel, S; Ngam, C; Sandbo, N; Torr, E1

Other Studies

8 other study(ies) available for y 27632 and colchicine

ArticleYear
Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle.
    Journal of muscle research and cell motility, 2001, Volume: 22, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Antineoplastic Agents; Aorta; Azepines; Calcium; Colchicine; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Male; Microtubules; Muscle Contraction; Muscle, Smooth, Vascular; Nocodazole; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents

2001
Localised depletion of polymerised actin at the front of Walker carcinosarcoma cells increases the speed of locomotion.
    Cell motility and the cytoskeleton, 2002, Volume: 53, Issue:3

    Topics: Actinin; Actins; Amides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma 256, Walker; Cell Membrane; Cell Movement; Cell Polarity; Cell Size; Cell Surface Extensions; Colchicine; Diacetyl; Enzyme Inhibitors; Humans; Myosins; Pyridines; Thiazoles; Thiazolidines

2002
Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways.
    Journal of cell science, 2003, Mar-01, Volume: 116, Issue:Pt 5

    Topics: Amides; Androstadienes; Cell Movement; Colchicine; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Microtubules; Myosin Light Chains; Neutrophils; Oligopeptides; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Wortmannin

2003
Astrocyte stellation induced by Rho kinase inhibitors in culture.
    Brain research. Developmental brain research, 2003, Jun-12, Volume: 143, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Animals; Astrocytes; Carbazoles; Cell Size; Cells, Cultured; Cerebral Cortex; Colchicine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gout Suppressants; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Phalloidine; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; rho-Associated Kinases

2003
Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Actins; Amides; Bacterial Proteins; Bacterial Toxins; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Colchicine; Connective Tissue Growth Factor; Cytochalasin D; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Nocodazole; Paclitaxel; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Stress, Mechanical; Thiazoles; Thiazolidines

2003
Closure of supporting cell scar formations requires dynamic actin mechanisms.
    Hearing research, 2007, Volume: 232, Issue:1-2

    Topics: Actins; Amides; Animals; Anti-Bacterial Agents; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Death; Cicatrix; Colchicine; Cytochalasin D; Gentamicins; Hair Cells, Auditory; Immunohistochemistry; Keratins; Microscopy, Confocal; Microscopy, Electron, Transmission; Microtubules; Myosins; Paclitaxel; Pyridines; Rana catesbeiana; Saccule and Utricle; Thiazolidines; Time Factors; Tissue Culture Techniques; Tubulin Modulators; Wound Healing

2007
Fibroblast cytoskeletal remodeling contributes to connective tissue tension.
    Journal of cellular physiology, 2011, Volume: 226, Issue:5

    Topics: Amides; Animals; Cell Shape; Colchicine; Connective Tissue; Cytoskeleton; Elasticity; Fibroblasts; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neuropeptides; Protein Kinase Inhibitors; Pseudopodia; Pyridines; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; rho-Associated Kinases; Sodium Azide; Stress, Mechanical; Time Factors; Tubulin Modulators

2011
Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2.
    The Journal of biological chemistry, 2013, May-31, Volume: 288, Issue:22

    Topics: Adaptor Proteins, Signal Transducing; Amides; Anilides; Benzamides; Cell Differentiation; Cells, Cultured; Colchicine; DNA-Binding Proteins; Enzyme Inhibitors; Formins; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Microtubules; Myofibroblasts; Oncogene Proteins, Fusion; Paclitaxel; Protein Transport; Pyridines; Serum Response Factor; Smad Proteins; Stress Fibers; Trans-Activators; Transforming Growth Factor beta; Tubulin Modulators

2013