Page last updated: 2024-09-03

y 27632 and bq 123

y 27632 has been researched along with bq 123 in 4 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(bq 123)
Trials
(bq 123)
Recent Studies (post-2010) (bq 123)
1,92438911,39163152

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)bq 123 (IC50)
Endothelin-1 receptorHomo sapiens (human)0.017
Endothelin-1 receptorRattus norvegicus (Norway rat)0.014

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herzog, M; Scherer, EQ; Wangemann, P1
Chiba, Y; Misawa, M; Sakai, H1
Gebb, SA; Homma, N; Karoor, V; McMurtry, IF; Morio, Y; Nagaoka, T; Oka, M; Ota, H1
Kim, SC; Lee, MY; Lee, SY; Myung, SC; Park, SH; Yum, SH1

Other Studies

4 other study(ies) available for y 27632 and bq 123

ArticleYear
Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide.
    Stroke, 2002, Volume: 33, Issue:12

    Topics: Amides; Animals; Antihypertensive Agents; Arteries; Calcitonin Gene-Related Peptide; Calcium; Dansyl Compounds; Ear, Inner; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Gerbillinae; Intracellular Signaling Peptides and Proteins; Myosin-Light-Chain Phosphatase; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Pyridines; Receptor, Endothelin A; Regional Blood Flow; rho-Associated Kinases; Signal Transduction; Vascular Patency; Vasoconstriction; Vasospasm, Intracranial

2002
Endothelin-1-induced translocation of RhoA is mediated by endothelin ET(A) receptors in rat bronchial smooth muscle.
    European journal of pharmacology, 2005, Jul-11, Volume: 517, Issue:3

    Topics: Amides; Animals; Atropine; Blotting, Western; Bronchi; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Transport; Pyridines; Rats; Rats, Wistar; Receptor, Endothelin A; rhoA GTP-Binding Protein; Time Factors

2005
Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:6

    Topics: Amides; Animals; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Activation; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Peptides, Cyclic; Perfusion; Potassium Chloride; Pulmonary Artery; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Serotonin; Signal Transduction; Vasoconstriction

2007
Contractile changes of the clitoral cavernous smooth muscle in female rabbits with experimentally induced overactive bladder.
    The journal of sexual medicine, 2008, Volume: 5, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenergic alpha-Agonists; Amides; Animals; Antihypertensive Agents; Calcium Channel Agonists; Clitoris; Dose-Response Relationship, Drug; Endothelin-1; Female; Isometric Contraction; Models, Animal; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Oligopeptides; Peptides, Cyclic; Phenylephrine; Piperidines; Potassium; Pyridines; Rabbits; Urinary Bladder, Overactive; Vasodilator Agents

2008