y 27632 has been researched along with blister in 48 studies
Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (blister) | Trials (blister) | Recent Studies (post-2010) (blister) |
---|---|---|---|---|---|
1,924 | 3 | 891 | 460 | 0 | 279 |
Protein | Taxonomy | y 27632 (IC50) | blister (IC50) |
---|---|---|---|
Myosin-2 heavy chain | Dictyostelium discoideum | 4.9 | |
Myosin-9 | Homo sapiens (human) | 4 | |
Myosin-10 | Homo sapiens (human) | 4.6 | |
Myosin-7 | Sus scrofa (pig) | 1.2 | |
Myosin-4 | Oryctolagus cuniculus (rabbit) | 0.22 | |
Myosin-14 | Mus musculus (house mouse) | 3.2 | |
Nonmuscle myosin heavy chain | Gallus gallus (chicken) | 1.8 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 21 (43.75) | 29.6817 |
2010's | 26 (54.17) | 24.3611 |
2020's | 1 (2.08) | 2.80 |
Authors | Studies |
---|---|
Sawin, KE | 1 |
Baum, B; Cramer, LP; McGee, KM; Rosenblatt, J | 1 |
Gallo, G | 1 |
Bresnick, AR; Dulyaninova, NG; Matsuda, M; Mochizuki, N; Ohba, Y; Parrini, MC; Yoshizaki, H | 1 |
Amano, M; Kaibuchi, K; Kaneko, T; Katsumi, A; Kawabata, S; Nakayama, M; Takefuji, M | 1 |
Kanada, M; Nagasaki, A; Uyeda, TQ | 1 |
Fabian, L; Forer, A | 1 |
Orlando, KA; Pittman, RN; Stone, NL | 1 |
Hosoya, H; Inoue, N; Kinoshita, N; Miyake, Y; Nishimura, K; Yonemura, S | 1 |
Elson, EL; Fee, JA; Rémond, MC; Taber, LA | 1 |
Ahuja, P; Ehler, E; Perriard, E; Perriard, JC; Trimble, W | 1 |
Johnson, GJ; Krumwiede, MD; Leis, LA; White, JG | 1 |
Auger, JM; Calaminus, SD; Machesky, LM; McCarty, OJ; Wakelam, MJ; Watson, SP | 1 |
Blum, M; Mihatsch, J; Möller, W; Rösner, H; Wassermann, T | 1 |
Martens, JC; Radmacher, M | 1 |
Bastmeyer, M; Bischofs, IB; Klein, F; Lehnert, D; Schwarz, US | 1 |
Alexandrova, AY; Shutova, MS; Vasiliev, JM | 1 |
Means, AR; Sandquist, JC | 1 |
Du, G; Frohman, MA | 1 |
Benoit, M; Cuerrier, CM; Gobeil, F; Grandbois, M; Guillemette, G | 1 |
Abe, T; Hara, Y; Tanaka, M | 1 |
Grinnell, F; Ho, CH; Rhee, S | 1 |
Ramachandran, C; Srinivas, SP | 1 |
Pasapera, AM; Rericha, E; Schlaepfer, DD; Schneider, IC; Waterman, CM | 1 |
Lemaire, P; Munro, E; Robin, F; Sherrard, K | 1 |
Das, T; Denizot, M; Gasque, P; Hoarau, JJ; Jaffar-Bandjee, MC; Krejbich-Trotot, P | 1 |
Cho, C; Choi, H; Han, C; Jin, S; Kim, D; Kim, DH; Kim, J; Kwon, JT; Lee, B; Lifirsu, E; Park, I; Park, WJ; Park, ZY | 1 |
Hamao, K; Hosoya, H; Kamijo, K; Kimura, H; Kondo, T; Morita, M; Takahashi, M | 1 |
Adelstein, RS; Kim, JH | 1 |
Borges, RM; Forti, FL; Lamers, ML; Santos, MF; Yan, CY | 1 |
Guo, YM; Hirokawa, M; Komatsuda, A; Michishita, Y; Nara, M; Nunomura, W; Sawada, K; Tagawa, H; Takahashi, M; Takahashi, N; Takakuwa, Y; Ubukawa, K | 1 |
DiPaolo, BC; Margulies, SS | 1 |
Janshoff, A; Schneider, D | 1 |
Aihara, Y; Akasu, T; Fujita, S; Ishiguro, T; Nakagama, H; Ohata, H; Okamoto, K; Sakai, H; Sato, A; Sekine, S; Taniguchi, H | 1 |
Liu, F; Marinkovic, A; Mih, JD; Sharif, AS; Tschumperlin, DJ | 1 |
Bodennec, S; Delanoë-Ayari, H; Ferri, K; Mertani, HC; Mgharbel, A; Rieu, JP; Stirbat, TV | 1 |
Banks, P; Blanco Suarez, EM; Cockbill, LM; Hanley, JG; Murk, K | 1 |
Agbani, EO; Brown, E; Collins, PW; Cosemans, JM; Heemskerk, JW; Hers, I; Mattheij, NJ; Poole, AW; van den Bosch, MT; Williams, CM | 1 |
Morgan, JR; Susienka, MJ; Wilks, BT | 1 |
Huang, J; Lin, F; Pang, M; Teng, Y; Xiong, C; Yuan, Y | 1 |
Alon, R; Barzilai, S; Feigelson, SW; Golani, O; Klein, E; Morrell, S; Nourshargh, S; Roncato, F; Stoler-Barak, L; Yadav, SK; Zemel, A | 1 |
Chinnathambi, S; Sander, EA; Selby, JC; Zarkoob, H | 1 |
Brassart, B; Brassart-Pasco, S; Da Silva, J; Donet, M; Hague, F; Hinek, A; Maquart, FX; Michel, J; Monboisse, JC; Ouadid-Ahidouch, H; Ramont, L; Seurat, E; Terryn, C; Velard, F | 1 |
Baker, BM; Davidson, CD; Lin, D; Wang, WY | 1 |
Paul, CD; So, WY; Staunton, JR; Tanner, K | 1 |
Chang, JS; Chang, SW; Chou, SF; Ho, WT; Hwang, WL; Jou, TS; Shih, PJ; Wang, IJ; Yang, MH | 1 |
Aman, ZM; Chin, IL; Choi, YS; Guan, KL; Han, DW; Hepburn, MS; Holle, AW; Hwang, Y; Jeong, JH; Jeong, K; Kennedy, BF; Major, LG; Park, HW; Sanderson, RW; Spatz, JP; Young, JL | 1 |
Berger, W; Bugyik, E; Czirok, A; Dome, B; Hegedus, B; Isai, DG; Kovacs, I; Mehes, E; Neufeld, Z; Paku, S; Stockhammer, P; Szeder, B; Tarnoki-Zach, J; Thomas, SM | 1 |
48 other study(ies) available for y 27632 and blister
Article | Year |
---|---|
The spindle gets bigger.
Topics: Actins; Amides; Centrosome; Enzyme Inhibitors; Eukaryotic Cells; Heterocyclic Compounds, 4 or More Rings; Models, Biological; Myosin Type II; Nuclear Envelope; Pyridines; RNA Interference; Spindle Apparatus; Time Factors | 2004 |
Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly.
Topics: Actins; Amides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Polarity; Centrosome; Cross-Linking Reagents; Drosophila; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Hybridomas; Lectins; Marine Toxins; Marsupialia; Mitosis; Models, Biological; Movement; Myosin Type II; Nuclear Envelope; Pyridines; RNA Interference; Spindle Apparatus; Thiazoles; Thiazolidines; Time Factors | 2004 |
Myosin II activity is required for severing-induced axon retraction in vitro.
Topics: Actins; Amides; Animals; Axons; Axotomy; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ganglia, Spinal; Growth Cones; Heterocyclic Compounds, 4 or More Rings; Immunohistochemistry; Microscopy, Video; Myosin Type II; Neurons; Organ Culture Techniques; Peptides; Pyridines; Retina; Retrograde Degeneration; Thiazoles; Thiazolidines; Time Factors; Tubulin | 2004 |
Cell type-specific regulation of RhoA activity during cytokinesis.
Topics: Adenoviridae; ADP Ribose Transferases; Amides; Animals; Azepines; Botulinum Toxins; Cell Line; Cell Membrane; Cytokinesis; DNA, Complementary; Fluorescence Resonance Energy Transfer; G1 Phase; G2 Phase; Gene Expression Regulation; Genes, Dominant; Green Fluorescent Proteins; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Mutation; Naphthalenes; NIH 3T3 Cells; Plasmids; Proto-Oncogene Proteins; Pyridines; Rats; rhoA GTP-Binding Protein; Time Factors | 2004 |
Rho-kinase and myosin II activities are required for cell type and environment specific migration.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cell Culture Techniques; Cell Movement; Cell Nucleus; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Epithelial Cells; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Humans; Intracellular Signaling Peptides and Proteins; Macrophages; Monomeric GTP-Binding Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Type II; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases | 2005 |
Adhesion-dependent and contractile ring-independent equatorial furrowing during cytokinesis in mammalian cells.
Topics: Amides; Animals; Cell Adhesion; Cell Line; Cytokinesis; Dictyostelium; Fibronectins; Heterocyclic Compounds, 4 or More Rings; Humans; Pyridines; Rats | 2005 |
Redundant mechanisms for anaphase chromosome movements: crane-fly spermatocyte spindles normally use actin filaments but also can function without them.
Topics: Actin Cytoskeleton; Amides; Anaphase; Animals; Azepines; Chromosomes; Diacetyl; Diptera; Drosophila melanogaster; Heterocyclic Compounds, 4 or More Rings; Locusta migratoria; Male; Naphthalenes; Pyridines; Sea Urchins; Spermatocytes; Spindle Apparatus | 2005 |
Rho kinase regulates fragmentation and phagocytosis of apoptotic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Caspase Inhibitors; Caspases; Cell Membrane; Chlorocebus aethiops; COS Cells; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Intracellular Signaling Peptides and Proteins; Marine Toxins; Muscle Contraction; Myosins; PC12 Cells; Phagocytosis; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Rats; rho-Associated Kinases; RNA, Small Interfering; Thiazoles; Thiazolidines | 2006 |
Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation.
Topics: Actomyosin; Adherens Junctions; Amides; Animals; Cell Adhesion Molecules; Cell Line; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Dogs; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Lysophospholipids; Membrane Proteins; Mice; Microscopy, Electron, Transmission; Myosin Type II; Nonmuscle Myosin Type IIB; Occludin; Platelet-Derived Growth Factor; Pyridines; Rats; rho GTP-Binding Proteins; RNA, Small Interfering; Tight Junctions; Vinculin | 2006 |
Myosin-based contraction is not necessary for cardiac c-looping in the chick embryo.
Topics: Amides; Animals; Azepines; Chick Embryo; Chickens; Cytoskeleton; Diacetyl; Enzyme Inhibitors; Heart; Heterocyclic Compounds, 4 or More Rings; Myocardial Contraction; Myosin Light Chains; Naphthalenes; Organ Culture Techniques; Phosphorylation; Pyridines; Somites; Torsion Abnormality | 2006 |
Probing the role of septins in cardiomyocytes.
Topics: Actinin; Amides; Animals; Cell Cycle Proteins; Cells, Cultured; Cytochalasin D; Cytokinesis; Cytoskeletal Proteins; Enzyme Inhibitors; GTP Phosphohydrolases; GTP-Binding Proteins; Heart; Heterocyclic Compounds, 4 or More Rings; Mice; Microtubules; Models, Biological; Myocardium; Myocytes, Cardiac; Nonmuscle Myosin Type IIB; Pyridines; Rats; Schizosaccharomyces pombe Proteins; Septins; Spindle Apparatus; Time Factors; Transcription Factors | 2006 |
The critical role of myosin IIA in platelet internal contraction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actins; Adult; Amides; Blood Platelets; Cell Shape; Heterocyclic Compounds, 4 or More Rings; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Microscopy, Electron, Transmission; Myosin Light Chains; Nonmuscle Myosin Type IIA; Phosphorylation; Platelet Aggregation; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases | 2007 |
MyosinIIa contractility is required for maintenance of platelet structure during spreading on collagen and contributes to thrombus stability.
Topics: Actins; Amides; Blood Platelets; Cell Movement; Collagen; Cytoskeleton; Heterocyclic Compounds, 4 or More Rings; Humans; Models, Biological; Myosin Light Chains; Nonmuscle Myosin Type IIA; Phosphorylation; Platelet Aggregation; Pyridines; rho-Associated Kinases; Thrombosis | 2007 |
Attenuation of actinomyosinII contractile activity in growth cones accelerates filopodia-guided and microtubule-based neurite elongation.
Topics: Actomyosin; Amides; Animals; Central Nervous System; Chick Embryo; Contractile Proteins; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibronectins; Growth Cones; Heterocyclic Compounds, 4 or More Rings; Laminin; Microtubules; Neural Pathways; Neurites; Neurogenesis; Nocodazole; Paclitaxel; Pseudopodia; Pyridines; rho GTP-Binding Proteins; Tubulin Modulators | 2007 |
Softening of the actin cytoskeleton by inhibition of myosin II.
Topics: Actins; Amides; Animals; Biomechanical Phenomena; Cell Line; Cell Shape; Cytoskeleton; Elasticity; Enzyme Inhibitors; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Microscopy, Atomic Force; Myosin Type II; Pyridines; Rats; rho-Associated Kinases | 2008 |
Filamentous network mechanics and active contractility determine cell and tissue shape.
Topics: Amides; Animals; Biomechanical Phenomena; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Shape; Computer Simulation; Cytoskeleton; Elasticity; Heterocyclic Compounds, 4 or More Rings; Mice; Models, Biological; Myosin Type II; Pyridines; Rats; rho-Associated Kinases; Tissue Engineering | 2008 |
Regulation of polarity in cells devoid of actin bundle system after treatment with inhibitors of myosin II activity.
Topics: Actins; Amides; Animals; Cell Line; Cell Movement; Cell Polarity; Cell Shape; Demecolcine; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Microtubules; Models, Biological; Myosin Type II; Pyridines; Rats; Wound Healing | 2008 |
The C-terminal tail region of nonmuscle myosin II directs isoform-specific distribution in migrating cells.
Topics: Amides; Animals; Cell Line; Cell Movement; Enzyme Inhibitors; Fibroblasts; Fluorescence Recovery After Photobleaching; Heterocyclic Compounds, 4 or More Rings; Humans; Myosin Heavy Chains; Nonmuscle Myosin Type IIA; Nonmuscle Myosin Type IIB; Protein Isoforms; Pyridines; Recombinant Fusion Proteins | 2008 |
A lipid-signaled myosin phosphatase surge disperses cortical contractile force early in cell spreading.
Topics: Amides; Animals; Cell Membrane; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Lipids; Myosin Type II; Myosin-Light-Chain Phosphatase; Phosphatidic Acids; Phospholipase D; Pyridines; rho-Associated Kinases; RNA Interference; Second Messenger Systems | 2009 |
Real-time monitoring of angiotensin II-induced contractile response and cytoskeleton remodeling in individual cells by atomic force microscopy.
Topics: Actins; Amides; Angiotensin II; Azepines; Cell Line; Cell Size; Cytological Techniques; Cytoskeleton; Elastic Modulus; Heterocyclic Compounds, 4 or More Rings; Humans; Kidney; Microscopy, Atomic Force; Microscopy, Confocal; Muscle Contraction; Pyridines; Receptor, Angiotensin, Type 1 | 2009 |
Roles of focal adhesions and fibronectin-mediated cohesion in proliferation of confluent fibroblasts.
Topics: Adult; Amides; Animals; Antibodies, Monoclonal; Antioxidants; Ascorbic Acid; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Extracellular Matrix; Fibroblasts; Fibronectins; Focal Adhesions; Heterocyclic Compounds, 4 or More Rings; Humans; Integrin alpha5beta1; Middle Aged; Myosin Type II; Paxillin; Pyridines; rho-Associated Kinases; Stress Fibers; Transforming Growth Factor beta1; Vinculin | 2009 |
Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis.
Topics: Actins; Amides; Cell Aggregation; Cell Culture Techniques; Cell Line, Transformed; Cell Movement; Cell Shape; Collagen; Enzyme Inhibitors; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Humans; Intercellular Signaling Peptides and Proteins; Lysophospholipids; Male; Myosin Type II; Oncogene Protein p21(ras); Platelet-Derived Growth Factor; Pyridines; rho-Associated Kinases; Serum; Sphingosine; Vinculin | 2010 |
Formation and disassembly of adherens and tight junctions in the corneal endothelium: regulation by actomyosin contraction.
Topics: Actins; Actomyosin; Adherens Junctions; Amides; Animals; Blotting, Western; Cadherins; Calcium; Cattle; Cell Culture Techniques; Electric Impedance; Endothelium, Corneal; Fluorescent Antibody Technique, Indirect; Heterocyclic Compounds, 4 or More Rings; Membrane Proteins; Myosin Light Chains; Phosphoproteins; Phosphorylation; Pyridines; rhoA GTP-Binding Protein; Tight Junctions; Zonula Occludens-1 Protein | 2010 |
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.
Topics: Amides; Animals; Cells, Cultured; Extracellular Matrix; Fibroblasts; Fibronectins; Focal Adhesions; Heterocyclic Compounds, 4 or More Rings; Mice; Myosin Type II; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Structure-Activity Relationship; Vinculin | 2010 |
Sequential activation of apical and basolateral contractility drives ascidian endoderm invagination.
Topics: Amides; Animals; Endoderm; Heterocyclic Compounds, 4 or More Rings; Models, Biological; Myosins; Pyridines; rhoA GTP-Binding Protein; Urochordata | 2010 |
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
Topics: Alphavirus Infections; Amides; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Bystander Effect; Caspase 8; Caspase Inhibitors; Cell Line; Cell Survival; Cells, Cultured; Chikungunya virus; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Fibroblasts; Genistein; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Host-Pathogen Interactions; Humans; Macrophages; Oligopeptides; Pyridines; Vero Cells | 2011 |
Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.
Topics: Amides; Amino Acid Sequence; Animals; Cell Movement; Enzyme Inhibitors; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Molecular Sequence Data; Myosin Light Chains; Myosin Type II; NIH 3T3 Cells; Pyridines; RNA Interference | 2011 |
Enhancement of myosin II/actin turnover at the contractile ring induces slower furrowing in dividing HeLa cells.
Topics: Actins; Amides; Cell Membrane; Gene Expression Regulation; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Mitosis; Myosin Light Chains; Myosin Type II; Protein Transport; Pyridines | 2011 |
LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells.
Topics: Amides; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Female; Heterocyclic Compounds, 4 or More Rings; Lysophospholipids; Mice; Myosin Light Chains; Pertussis Toxin; Phosphorylation; Pyridines; Receptors, Lysophosphatidic Acid; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction | 2011 |
Rho signaling pathway and apical constriction in the early lens placode.
Topics: Actins; Actomyosin; ADP Ribose Transferases; Amides; Animals; Botulinum Toxins; Chick Embryo; Chickens; Cytochalasin D; Cytoskeleton; Ectoderm; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Heterocyclic Compounds, 4 or More Rings; Immunohistochemistry; Lens, Crystalline; Myosin Type II; Nucleic Acid Synthesis Inhibitors; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2011 |
Enucleation of human erythroblasts involves non-muscle myosin IIB.
Topics: Amides; Aminoquinolines; Cells, Cultured; Cytokinesis; Enzyme Inhibitors; Erythroblasts; Erythroid Precursor Cells; Erythropoiesis; Green Fluorescent Proteins; Heterocyclic Compounds, 4 or More Rings; Humans; Microfilament Proteins; Myosins; Nonmuscle Myosin Type IIA; Nonmuscle Myosin Type IIB; Peptide Fragments; Protein Isoforms; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Recombinant Fusion Proteins; rho-Associated Kinases | 2012 |
Rho kinase signaling pathways during stretch in primary alveolar epithelia.
Topics: Actins; Amides; Animals; Azepines; Cardiac Myosins; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Epithelial Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mechanical Phenomena; Mechanotransduction, Cellular; Models, Biological; Myosin Light Chains; Naphthalenes; Phosphorylation; Pulmonary Alveoli; Pyridines; Rats, Sprague-Dawley; Respiration, Artificial; Respiratory Mucosa; rho-Associated Kinases; rhoA GTP-Binding Protein | 2012 |
Inhibition of actin dynamics during epithelial-to-mesenchymal transition.
Topics: Actins; Amides; Animals; Cell Line; Cell Shape; Dielectric Spectroscopy; Epithelial-Mesenchymal Transition; Heterocyclic Compounds, 4 or More Rings; Mice; Microscopy, Fluorescence; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Transforming Growth Factor beta | 2012 |
Induction of the stem-like cell regulator CD44 by Rho kinase inhibition contributes to the maintenance of colon cancer-initiating cells.
Topics: Amides; Animals; Apoptosis; Blotting, Western; Cell Proliferation; Colonic Neoplasms; Enzyme Inhibitors; Gene Expression Profiling; Hep G2 Cells; Heterocyclic Compounds, 4 or More Rings; HT29 Cells; Humans; Hyaluronan Receptors; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms, Experimental; Neoplastic Stem Cells; Oligonucleotide Array Sequence Analysis; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA Interference; Spheroids, Cellular; Transplantation, Heterologous; Tumor Cells, Cultured | 2012 |
Matrix stiffness reverses the effect of actomyosin tension on cell proliferation.
Topics: Actin Cytoskeleton; Actomyosin; Amides; Animals; Cantharidin; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dogs; Extracellular Matrix; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Humans; Madin Darby Canine Kidney Cells; Mesenchymal Stem Cells; Mice; NIH 3T3 Cells; Pyridines; Rats | 2012 |
Fine tuning of tissues' viscosity and surface tension through contractility suggests a new role for α-catenin.
Topics: Actin Cytoskeleton; alpha Catenin; Amides; Animals; Biomechanical Phenomena; Cell Adhesion; Cell Communication; Cell Line, Tumor; Cell Movement; Computer Simulation; Embryo, Mammalian; Gene Knockout Techniques; Heterocyclic Compounds, 4 or More Rings; Mechanotransduction, Cellular; Mice; Nocodazole; Pyridines; Surface Tension; Viscosity | 2013 |
The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology.
Topics: Actin-Related Protein 2-3 Complex; Amides; Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Central Nervous System; Colforsin; Enzyme Inhibitors; Fibroblasts; HEK293 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Myosin Type II; Nuclear Proteins; Pyridines; Rats; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Thiazoles; Thiones; Uracil; Vasodilator Agents; Wiskott-Aldrich Syndrome Protein, Neuronal | 2013 |
Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets.
Topics: Acetazolamide; Actomyosin; Amides; Animals; Anoctamins; Blood Coagulation Disorders; Blood Platelets; Carotid Artery Thrombosis; Cell Adhesion; Cell Membrane; Cell Shape; Cell Size; Cell-Derived Microparticles; Chlorides; Collagen; Cytochalasin D; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Microtubules; Phospholipid Transfer Proteins; Pyridines; Sodium; Thrombin; Thrombosis; Water | 2015 |
Quantifying the kinetics and morphological changes of the fusion of spheroid building blocks.
Topics: Amides; Cell Fusion; Cell Shape; Cells, Cultured; Chondrocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Kinetics; MCF-7 Cells; Microscopy, Fluorescence; Pyridines; Spheroids, Cellular; Time-Lapse Imaging; Tissue Scaffolds | 2016 |
Substrate stiffness promotes latent TGF-β1 activation in hepatocellular carcinoma.
Topics: Amides; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytoskeleton; Extracellular Matrix; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Integrin beta1; Liver Neoplasms; Oligopeptides; Protein Binding; Pyridines; rho GTP-Binding Proteins; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1; Up-Regulation | 2017 |
Leukocytes Breach Endothelial Barriers by Insertion of Nuclear Lobes and Disassembly of Endothelial Actin Filaments.
Topics: Actin Cytoskeleton; Actins; Amides; Antigens, CD; Cadherins; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Heterocyclic Compounds, 4 or More Rings; Humans; Interleukin-1beta; Leukocytes; Muscle Contraction; Myosin Type II; Neutrophils; Pyridines; rho-Associated Kinases; T-Lymphocytes; Time-Lapse Imaging; Transendothelial and Transepithelial Migration | 2017 |
Substrate deformations induce directed keratinocyte migration.
Topics: Amides; Cell Line; Cell Movement; Heterocyclic Compounds, 4 or More Rings; Humans; Keratinocytes; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Wound Healing | 2018 |
Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA.
Topics: Amides; Calcium; Cell Communication; Cell Line, Tumor; Elastin; Extracellular Matrix Proteins; Extracellular Vesicles; Heterocyclic Compounds, 4 or More Rings; HSP90 Heat-Shock Proteins; Humans; Neoplasms; Peptide Fragments; Pyridines; Receptors, Laminin; rho-Associated Kinases; Ribosomal Proteins; Signal Transduction | 2019 |
Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration.
Topics: Acrylic Resins; Actomyosin; Amides; Animals; Biocompatible Materials; Cell Line, Tumor; Cell Movement; Dextrans; Elastic Modulus; Extracellular Matrix; Fibroblasts; Heterocyclic Compounds, 4 or More Rings; Humans; Intravital Microscopy; Marine Toxins; Materials Testing; Methacrylates; Mice; Microscopy, Confocal; NIH 3T3 Cells; Oxazoles; Pyridines; Time-Lapse Imaging | 2019 |
High-frequency microrheology in 3D reveals mismatch between cytoskeletal and extracellular matrix mechanics.
Topics: Actomyosin; Amides; Cell Culture Techniques; Cell Movement; Cytoskeleton; Extracellular Matrix; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrogels; Laminin; Marine Toxins; MCF-7 Cells; Mechanotransduction, Cellular; Oxazoles; Pyridines; Rheology; Viscosity | 2019 |
Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics.
Topics: Actin-Related Protein 2-3 Complex; Actins; Amides; Animals; Cattle; Cell Movement; Cells, Cultured; Endothelium, Corneal; Heterocyclic Compounds, 4 or More Rings; Myosin Type II; Pyridines; Rabbits; rho-Associated Kinases; Wound Healing | 2019 |
Volume Adaptation Controls Stem Cell Mechanotransduction.
Topics: Actin Cytoskeleton; Actomyosin; Acyltransferases; Adipogenesis; Amides; Cell Cycle Proteins; Cell Differentiation; Cell Encapsulation; Cell Nucleus; Cell Size; Core Binding Factor Alpha 1 Subunit; Gelatin; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrogels; Lamin Type A; Mechanotransduction, Cellular; Mesenchymal Stem Cells; Myosin Type II; Osteogenesis; PPAR gamma; Pyridines; rho-Associated Kinases; Trans-Activators; Transcription Factors | 2019 |
Multicellular contractility contributes to the emergence of mesothelioma nodules.
Topics: Actins; Amides; Animals; Cell Count; Cell Line, Tumor; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mesothelioma, Malignant; Mice, SCID; Myosins; Pyridines; Stochastic Processes; Time-Lapse Imaging; Xenograft Model Antitumor Assays | 2020 |