Compounds > y 27632
Page last updated: 2024-09-03

y 27632 and bisindolylmaleimide iv

y 27632 has been researched along with bisindolylmaleimide iv in 3 studies

Compound Research Comparison

Studies
(y 27632)		Trials
(y 27632)		Recent Studies (post-2010)
(y 27632)		Studies
(bisindolylmaleimide iv)		Trials
(bisindolylmaleimide iv)		Recent Studies (post-2010) (bisindolylmaleimide iv)
1,92438911704

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)bisindolylmaleimide iv (IC50)
Serine/threonine-protein kinase D3Homo sapiens (human)0.19
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)2.955
Protein kinase C gamma typeHomo sapiens (human)0.19
Protein kinase C alpha typeRattus norvegicus (Norway rat)0.325
Protein kinase C beta typeHomo sapiens (human)0.1805
Protein kinase C delta typeRattus norvegicus (Norway rat)0.325
Protein kinase C epsilon typeRattus norvegicus (Norway rat)0.325
Protein kinase C zeta typeRattus norvegicus (Norway rat)0.325
Cyclin-dependent kinase 4Homo sapiens (human)5.81
Protein kinase C alpha typeHomo sapiens (human)0.8945
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoformOryctolagus cuniculus (rabbit)3.2
G1/S-specific cyclin-D1Homo sapiens (human)5.81
Protein kinase C eta typeHomo sapiens (human)0.19
G1/S-specific cyclin-E1Homo sapiens (human)5.81
Cyclin-dependent kinase 2Homo sapiens (human)5.81
cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus (Norway rat)2.55
Protein kinase C iota typeHomo sapiens (human)0.19
Protein kinase C gamma typeRattus norvegicus (Norway rat)0.4
Protein kinase C beta typeRattus norvegicus (Norway rat)0.4
Protein kinase C epsilon typeHomo sapiens (human)3.853
Protein kinase C theta typeHomo sapiens (human)0.19
Protein kinase C zeta typeHomo sapiens (human)0.19
Protein kinase C delta typeHomo sapiens (human)0.19
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)1.19
Serine/threonine-protein kinase D1Homo sapiens (human)0.19
Protein kinase C eta typeRattus norvegicus (Norway rat)0.325
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)4.7
Protein kinase C theta typeRattus norvegicus (Norway rat)0.325

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caivano, M; Cohen, P; Davies, SP; Reddy, H1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1

Other Studies

3 other study(ies) available for y 27632 and bisindolylmaleimide iv

ArticleYear
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
    The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides

2000
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013