Page last updated: 2024-09-03

y 27632 and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

y 27632 has been researched along with benzyloxycarbonylleucyl-leucyl-leucine aldehyde in 4 studies

Compound Research Comparison

Studies
(y 27632)
Trials
(y 27632)
Recent Studies (post-2010)
(y 27632)
Studies
(benzyloxycarbonylleucyl-leucyl-leucine aldehyde)
Trials
(benzyloxycarbonylleucyl-leucyl-leucine aldehyde)
Recent Studies (post-2010) (benzyloxycarbonylleucyl-leucyl-leucine aldehyde)
1,92438912,47331,057

Protein Interaction Comparison

ProteinTaxonomyy 27632 (IC50)benzyloxycarbonylleucyl-leucyl-leucine aldehyde (IC50)
Proteasome subunit beta type-11Homo sapiens (human)1.9893
Calpain-9Homo sapiens (human)9.88
Proteasome subunit alpha type-7Homo sapiens (human)1.9893
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus3.9
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.8999
AromataseHomo sapiens (human)0.044
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)0.5
Proteasome subunit beta type-1Homo sapiens (human)1.0853
Proteasome subunit alpha type-1Homo sapiens (human)1.9893
Proteasome subunit alpha type-2Homo sapiens (human)1.9893
Proteasome subunit alpha type-3Homo sapiens (human)1.9893
Proteasome subunit alpha type-4Homo sapiens (human)1.9893
Proteasome subunit beta type-8Homo sapiens (human)1.9893
Proteasome subunit beta type-9Homo sapiens (human)1.9893
Proteasome subunit alpha type-5Homo sapiens (human)1.9893
Proteasome subunit beta type-4Homo sapiens (human)1.9893
Proteasome subunit beta type-6Homo sapiens (human)1.9893
Proteasome subunit beta type-5Homo sapiens (human)0.6088
Proteasome subunit beta type-10Homo sapiens (human)1.9893
Proteasome subunit beta type-3Homo sapiens (human)1.9893
Proteasome subunit beta type-2Homo sapiens (human)2.0443
Proteasome subunit alpha type-6Homo sapiens (human)1.9893
Proteasome subunit alpha-type 8Homo sapiens (human)1.9893
Proteasome subunit beta type-7Homo sapiens (human)1.9893

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Hashimoto, K; Kawagoe, J; Kurachi, H; Morishige, K; Ohta, T; Takahashi, K; Takahashi, T; Takata, K; Tsutsumi, S; Yin, L1
Byers, B; Byrne, J; Cord, B; Dolmetsch, RE; Gujar, P; Kee, K; Langston, W; Nguyen, HN; Palmer, TD; Pera, RR; Schüle, B; Shcheglovitov, A1
Bi, E; Hawke, DH; Huang, S; Jiang, Y; Li, X; Liu, DX; Lu, Z; Majumder, S; Wang, T; Wang, Y; Zheng, Y; Zhou, Q1

Other Studies

4 other study(ies) available for y 27632 and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Autocrine Communication; Cell Hypoxia; Cell Movement; Cell Nucleus; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Activation; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; Myosin Light Chains; Neovascularization, Pathologic; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; rho-Associated Kinases; Ubiquitination; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2008
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress.
    Cell stem cell, 2011, Mar-04, Volume: 8, Issue:3

    Topics: Amides; Amino Acid Substitution; Animals; Cell Death; Cell Differentiation; Dopamine; Female; Humans; Hydrogen Peroxide; Induced Pluripotent Stem Cells; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Leupeptins; Mesencephalon; Mice; Middle Aged; Mutation; Neurons; Oxidative Stress; Oxidopamine; Parkinson Disease; Phenotype; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases

2011
PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.
    Nature communications, 2014, Nov-21, Volume: 5

    Topics: Amides; Animals; Aurora Kinase B; Brain Neoplasms; Cardiac Myosins; Carrier Proteins; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cytokinesis; ErbB Receptors; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Leupeptins; Membrane Proteins; Mice; Mice, Nude; Mitosis; Myosin Light Chains; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Pyridines; Pyruvate Kinase; ras Proteins; rho-Associated Kinases; RNA Interference; RNA, Small Interfering; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2014