y 27632 has been researched along with bay 11-7082 in 6 studies
| Studies (y 27632) | Trials (y 27632) | Recent Studies (post-2010) (y 27632) | Studies (bay 11-7082) | Trials (bay 11-7082) | Recent Studies (post-2010) (bay 11-7082) |
|---|---|---|---|---|---|
| 1,924 | 3 | 891 | 570 | 1 | 383 |
| Protein | Taxonomy | y 27632 (IC50) | bay 11-7082 (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 0.82 | |
| Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | 2 | |
| Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | 2 | |
| Transcription factor p65 | Homo sapiens (human) | 2.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Hashimoto, K; Morishige, K; Murata, Y; Ogata, S; Shimizu, S; Tahara, M; Tasaka, K | 1 |
| Cho, KH; Han, JW; Jeong, KJ; Kang, J; Kim, YK; Lee, HY; Lee, J; Park, CG; Park, SY; Sohn, JS | 1 |
| Hong, KW; Kim, CD; Kwon, SM; Lee, SJ; Lee, SW; Lee, WS; Park, SY; Rhim, BY | 1 |
| Ding, R; Li, X; Liu, B; Ma, X; Zhao, D | 1 |
6 other study(ies) available for y 27632 and bay 11-7082
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells.
Topics: ADP Ribose Transferases; Adult; Amides; Botulinum Toxins; Cells, Cultured; Cervical Ripening; Cervix Uteri; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Humans; I-kappa B Proteins; Interleukin-1beta; Interleukin-8; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Phosphorylation; Pregnancy; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Stromal Cells; Sulfones; Time Factors; Transcription, Genetic | 2007 |
The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion.
Topics: Amides; Cell Line, Tumor; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Neoplasm Invasiveness; NF-kappa B; Nitriles; Ovarian Neoplasms; Peptide Hydrolases; Pyridines; rho-Associated Kinases; Sulfones; Urokinase-Type Plasminogen Activator | 2012 |
RhoA/ROCK-dependent pathway is required for TLR2-mediated IL-23 production in human synovial macrophages: suppression by cilostazol.
Topics: ADP Ribose Transferases; Amides; Animals; Arthritis, Rheumatoid; Botulinum Toxins; Case-Control Studies; Cilostazol; Cyclic AMP; Humans; Interleukin-23; Knee Joint; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred DBA; NF-kappa B; Nitriles; Pyridines; Reference Values; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Sulfones; Synovial Fluid; Teichoic Acids; Tetrazoles; Thionucleotides; Toll-Like Receptor 2 | 2013 |
Rho-kinase inhibitor treatment prevents pulmonary inflammation and coagulation in lipopolysaccharide-induced lung injury.
Topics: Acute Lung Injury; Amides; Animals; Blood Coagulation; Cell Line; Humans; Interleukins; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Nitriles; Pneumonia; Pyridines; rho-Associated Kinases; Sulfones | 2017 |